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14 results
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Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum.
Mund T, Gewies A, Schoenfeld N, Bauer MK, Grimm S. Mund T, et al. FASEB J. 2003 Apr;17(6):696-8. doi: 10.1096/fj.02-0657fje. Epub 2003 Feb 19. FASEB J. 2003. PMID: 12594175
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases.
Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, Waddell MB, Jäkel H, Kullmann M, Kriwacki RW, Hengst L. Grimmler M, et al. Among authors: mund t. Cell. 2007 Jan 26;128(2):269-80. doi: 10.1016/j.cell.2006.11.047. Cell. 2007. PMID: 17254966 Free article.
The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction.
Albayrak T, Scherhammer V, Schoenfeld N, Braziulis E, Mund T, Bauer MK, Scheffler IE, Grimm S. Albayrak T, et al. Among authors: mund t. Mol Biol Cell. 2003 Aug;14(8):3082-96. doi: 10.1091/mbc.e02-10-0631. Epub 2003 May 18. Mol Biol Cell. 2003. PMID: 12925748 Free PMC article.
Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2.
Mund T, Pelham HR. Mund T, et al. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11429-34. doi: 10.1073/pnas.0911714107. Epub 2010 Jun 7. Proc Natl Acad Sci U S A. 2010. PMID: 20534535 Free PMC article.
Ubiquitination of alpha-synuclein filaments by Nedd4 ligases.
Mund T, Masuda-Suzukake M, Goedert M, Pelham HR. Mund T, et al. PLoS One. 2018 Jul 18;13(7):e0200763. doi: 10.1371/journal.pone.0200763. eCollection 2018. PLoS One. 2018. PMID: 30021006 Free PMC article.
Substrate clustering potently regulates the activity of WW-HECT domain-containing ubiquitin ligases.
Mund T, Pelham HR. Mund T, et al. J Biol Chem. 2018 Apr 6;293(14):5200-5209. doi: 10.1074/jbc.RA117.000934. Epub 2018 Feb 20. J Biol Chem. 2018. PMID: 29463679 Free PMC article.
Activity-Based Probes for HECT E3 Ubiquitin Ligases.
Byrne R, Mund T, Licchesi JDF. Byrne R, et al. Among authors: mund t. Chembiochem. 2017 Jul 18;18(14):1415-1427. doi: 10.1002/cbic.201700006. Epub 2017 Jun 28. Chembiochem. 2017. PMID: 28425671 Free PMC article.
Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled.
Mund T, Graeb M, Mieszczanek J, Gammons M, Pelham HR, Bienz M. Mund T, et al. Open Biol. 2015 Dec;5(12):150185. doi: 10.1098/rsob.150185. Open Biol. 2015. PMID: 26701932 Free PMC article.
Peptide and small molecule inhibitors of HECT-type ubiquitin ligases.
Mund T, Lewis MJ, Maslen S, Pelham HR. Mund T, et al. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16736-41. doi: 10.1073/pnas.1412152111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385595 Free PMC article.
Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
Mund T, Pelham HR. Mund T, et al. EMBO Rep. 2009 May;10(5):501-7. doi: 10.1038/embor.2009.30. Epub 2009 Apr 3. EMBO Rep. 2009. PMID: 19343052 Free PMC article.
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