Muntean AG - Search Results

1

SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation.

Ropa J, Saha N, Hu H, Peterson LF, Talpaz M, Muntean AG. Ropa J, et al. Among authors: muntean ag. Haematologica. 2020 Sep 1;105(9):2273-2285. doi: 10.3324/haematol.2019.223883. Haematologica. 2020. PMID: 33054052 Free PMC article.

2

MLL-AF9 leukemia stem cells: hardwired or taking cues from the microenvironment?

Muntean AG, Hess JL. Muntean AG, et al. Cancer Cell. 2008 Jun;13(6):465-7. doi: 10.1016/j.ccr.2008.05.012. Cancer Cell. 2008. PMID: 18538728 Free article.

3

The PHD fingers of MLL block MLL fusion protein-mediated transformation.

Muntean AG, Giannola D, Udager AM, Hess JL. Muntean AG, et al. Blood. 2008 Dec 1;112(12):4690-3. doi: 10.1182/blood-2008-01-134056. Epub 2008 Sep 16. Blood. 2008. PMID: 18796627 Free PMC article.

4

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

Muntean AG, Tan J, Sitwala K, Huang Y, Bronstein J, Connelly JA, Basrur V, Elenitoba-Johnson KS, Hess JL. Muntean AG, et al. Cancer Cell. 2010 Jun 15;17(6):609-21. doi: 10.1016/j.ccr.2010.04.012. Cancer Cell. 2010. PMID: 20541477 Free PMC article.

5

PAFc, a key player in MLL-rearranged leukemogenesis.

Tan J, Muntean AG, Hess JL. Tan J, et al. Among authors: muntean ag. Oncotarget. 2010 Oct;1(6):461-5. doi: 10.18632/oncotarget.181. Oncotarget. 2010. PMID: 21037944 Free PMC article.

6

The pathogenesis of mixed-lineage leukemia.

Muntean AG, Hess JL. Muntean AG, et al. Annu Rev Pathol. 2012;7:283-301. doi: 10.1146/annurev-pathol-011811-132434. Epub 2011 Oct 17. Annu Rev Pathol. 2012. PMID: 22017583 Free PMC article. Review.

7

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.

Tan J, Jones M, Koseki H, Nakayama M, Muntean AG, Maillard I, Hess JL. Tan J, et al. Among authors: muntean ag. Cancer Cell. 2011 Nov 15;20(5):563-75. doi: 10.1016/j.ccr.2011.09.008. Cancer Cell. 2011. PMID: 22094252 Free PMC article.

8

ECSASB2 mediates MLL degradation during hematopoietic differentiation.

Wang J, Muntean AG, Hess JL. Wang J, et al. Among authors: muntean ag. Blood. 2012 Feb 2;119(5):1151-61. doi: 10.1182/blood-2011-06-362079. Epub 2011 Dec 15. Blood. 2012. PMID: 22174154 Free PMC article.

9

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Grembecka J, He S, Shi A, Purohit T, Muntean AG, Sorenson RJ, Showalter HD, Murai MJ, Belcher AM, Hartley T, Hess JL, Cierpicki T. Grembecka J, et al. Among authors: muntean ag. Nat Chem Biol. 2012 Jan 29;8(3):277-84. doi: 10.1038/nchembio.773. Nat Chem Biol. 2012. PMID: 22286128 Free PMC article.

10

The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.

Murai MJ, Pollock J, He S, Miao H, Purohit T, Yokom A, Hess JL, Muntean AG, Grembecka J, Cierpicki T. Murai MJ, et al. Among authors: muntean ag. Blood. 2014 Dec 11;124(25):3730-7. doi: 10.1182/blood-2014-01-550079. Epub 2014 Oct 10. Blood. 2014. PMID: 25305204 Free PMC article.

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