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Role of c-Kit and erythropoietin receptor in erythropoiesis.
Munugalavadla V, Kapur R. Munugalavadla V, et al. Crit Rev Oncol Hematol. 2005 Apr;54(1):63-75. doi: 10.1016/j.critrevonc.2004.11.005. Crit Rev Oncol Hematol. 2005. PMID: 15780908 Review.
The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.
Munugalavadla V, Vemula S, Sims EC, Krishnan S, Chen S, Yan J, Li H, Niziolek PJ, Takemoto C, Robling AG, Yang FC, Kapur R. Munugalavadla V, et al. Mol Cell Biol. 2008 Dec;28(23):7182-98. doi: 10.1128/MCB.00920-08. Epub 2008 Sep 22. Mol Cell Biol. 2008. PMID: 18809581 Free PMC article.
Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors.
Borneo J, Munugalavadla V, Sims EC, Vemula S, Orschell CM, Yoder M, Kapur R. Borneo J, et al. Among authors: munugalavadla v. Exp Hematol. 2007 Jul;35(7):1026-37. doi: 10.1016/j.exphem.2007.03.017. Exp Hematol. 2007. PMID: 17588471 Free PMC article.
p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway.
Wu X, Chen S, Orlando SA, Yuan J, Kim ET, Munugalavadla V, Mali RS, Kapur R, Yang FC. Wu X, et al. Among authors: munugalavadla v. J Biol Chem. 2011 Apr 15;286(15):13512-21. doi: 10.1074/jbc.M110.187351. Epub 2011 Feb 15. J Biol Chem. 2011. PMID: 21324896 Free PMC article.
ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells.
Kapur R, Shi J, Ghosh J, Munugalavadla V, Sims E, Martin H, Wei L, Mali RS. Kapur R, et al. Among authors: munugalavadla v. Oncotarget. 2016 Mar 29;7(13):16936-47. doi: 10.18632/oncotarget.7851. Oncotarget. 2016. PMID: 26943578 Free PMC article.
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.
Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, Bunting KD, Feng GS, Chan RJ, Zhang ZY, Kapur R. Mali RS, et al. Among authors: munugalavadla v. Blood. 2012 Sep 27;120(13):2669-78. doi: 10.1182/blood-2011-08-375873. Epub 2012 Jul 17. Blood. 2012. PMID: 22806893 Free PMC article.
p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis.
Krishnan S, Mali RS, Ramdas B, Sims E, Ma P, Ghosh J, Munugalavadla V, Hanneman P, Beane JD, Kapur R. Krishnan S, et al. Among authors: munugalavadla v. Blood. 2012 Apr 26;119(17):3951-61. doi: 10.1182/blood-2011-05-355602. Epub 2012 Feb 29. Blood. 2012. PMID: 22378847 Free PMC article.
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, Stern AM, Wen Q, Crispino JD, Boswell HS, Kapur R. Mali RS, et al. Among authors: munugalavadla v. Cancer Cell. 2011 Sep 13;20(3):357-69. doi: 10.1016/j.ccr.2011.07.016. Cancer Cell. 2011. PMID: 21907926 Free PMC article.
Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
Ma P, Vemula S, Munugalavadla V, Chen J, Sims E, Borneo J, Kondo T, Ramdas B, Mali RS, Li S, Hashino E, Takemoto C, Kapur R. Ma P, et al. Among authors: munugalavadla v. Mol Cell Biol. 2011 Oct;31(19):4052-62. doi: 10.1128/MCB.05750-11. Epub 2011 Jul 26. Mol Cell Biol. 2011. PMID: 21791602 Free PMC article.
The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor.
Ma P, Mali RS, Munugalavadla V, Krishnan S, Ramdas B, Sims E, Martin H, Ghosh J, Li S, Chan RJ, Krystal G, Craig AW, Takemoto C, Kapur R. Ma P, et al. Among authors: munugalavadla v. Blood. 2011 Sep 29;118(13):3459-69. doi: 10.1182/blood-2011-04-351809. Epub 2011 Jul 25. Blood. 2011. PMID: 21791431 Free PMC article.
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