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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Among authors: muranen t. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.
Starved epithelial cells uptake extracellular matrix for survival.
Muranen T, Iwanicki MP, Curry NL, Hwang J, DuBois CD, Coloff JL, Hitchcock DS, Clish CB, Brugge JS, Kalaany NY. Muranen T, et al. Nat Commun. 2017 Jan 10;8:13989. doi: 10.1038/ncomms13989. Nat Commun. 2017. PMID: 28071763 Free PMC article.
Moving Closer To Victory.
Muranen T, Brugge JS. Muranen T, et al. Cold Spring Harb Symp Quant Biol. 2016;81:281-288. doi: 10.1101/sqb.2016.81.031179. Epub 2017 Apr 17. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28416575 Review. No abstract available.
Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines.
Zhao W, Li J, Chen MM, Luo Y, Ju Z, Nesser NK, Johnson-Camacho K, Boniface CT, Lawrence Y, Pande NT, Davies MA, Herlyn M, Muranen T, Zervantonakis IK, von Euw E, Schultz A, Kumar SV, Korkut A, Spellman PT, Akbani R, Slamon DJ, Gray JW, Brugge JS, Lu Y, Mills GB, Liang H. Zhao W, et al. Among authors: muranen t. Cancer Cell. 2020 Dec 14;38(6):829-843.e4. doi: 10.1016/j.ccell.2020.10.008. Epub 2020 Nov 5. Cancer Cell. 2020. PMID: 33157050 Free PMC article.
Cell-cell and cell-matrix interactions.
Muranen T. Muranen T. Mol Biol Cell. 2013 Mar;24(6):671. doi: 10.1091/mbc.E12-12-0872. Mol Biol Cell. 2013. PMID: 23486395 Free PMC article. No abstract available.
95 results