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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1967 1
1976 1
1978 1
1979 1
1980 3
1981 2
1982 4
1983 4
1984 3
1985 6
1986 2
1987 3
1988 2
1989 4
1990 2
1991 5
1992 3
1993 5
1994 2
1995 2
1996 5
1997 4
1998 2
1999 5
2000 4
2001 4
2002 5
2003 2
2004 4
2005 8
2006 8
2007 3
2008 5
2009 7
2010 10
2011 7
2012 6
2013 15
2014 12
2015 10
2016 8
2017 3
2018 8
2019 7
2020 0
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188 results
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Page 1
Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor.
Uno T, et al. J Med Chem 2019. Among authors: Muraoka H. PMID 30525599
A novel series of HSP90 inhibitors were discovered by structure-activity relationship (SAR)-based optimization of an initial hit compound 11a having a 4-(4-(quinolin-3-yl)-1 H-indol-1-yl)benzamide structure. ...
A novel series of HSP90 inhibitors were discovered by structure-activity relationship (SAR)-based optimization of an initial hit compound 11 …
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