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Coffee and liver diseases.
Muriel P, Arauz J. Muriel P, et al. Fitoterapia. 2010 Jul;81(5):297-305. doi: 10.1016/j.fitote.2009.10.003. Epub 2009 Oct 13. Fitoterapia. 2010. PMID: 19825397 Review.
Prevention of CCL4-induced liver cirrhosis by silymarin.
Mourelle M, Muriel P, Favari L, Franco T. Mourelle M, et al. Among authors: Muriel P. Fundam Clin Pharmacol. 1989;3(3):183-91. doi: 10.1111/j.1472-8206.1989.tb00449.x. Fundam Clin Pharmacol. 1989. PMID: 2548940
Remission of liver fibrosis by interferon-alpha 2b.
Moreno MG, Muriel P. Moreno MG, et al. Among authors: Muriel P. Biochem Pharmacol. 1995 Aug 8;50(4):515-20. doi: 10.1016/0006-2952(95)00154-r. Biochem Pharmacol. 1995. PMID: 7646558
Protective effect of colchicine on acute liver damage induced by CCl4. Role of cytochrome P-450.
Martínez M, Mourelle M, Muriel P. Martínez M, et al. Among authors: Muriel P. J Appl Toxicol. 1995 Jan-Feb;15(1):49-52. doi: 10.1002/jat.2550150111. J Appl Toxicol. 1995. PMID: 7745225
CCl4-induced changes in hepatic biochemical parameters by reducing cytochrome P-450, by comparing the effects of colchicine and SKF 525-A, a well-known inhibitor of cytochrome P-450. Our results show that both drugs reduced the cytochrome P-450 content and p-nitroanisole o-demethylase activity to the same extent. ...
CCl4-induced changes in hepatic biochemical parameters by reducing cytochrome P-450, by comparing the effects of colchicine and SKF 5 …
Cimetidine prevents and partially reverses CCl4-induced liver cirrhosis.
Mera E, Muriel P, Castillo C, Mourelle M. Mera E, et al. Among authors: Muriel P. J Appl Toxicol. 1994 Mar-Apr;14(2):87-90. doi: 10.1002/jat.2550140205. J Appl Toxicol. 1994. PMID: 7913103
Male Wistar rats were used: animals in group 1 received CCl4 (0.04 g per 100 g, i.p.) three times a week for 8 weeks; group 2 was treated with CCl4 plus cimetidine (120 mg kg-1, p.o.) three times a week for 8 weeks; group 3 received CCl4 for 8 weeks and then cimetidine for 4 weeks. ...Intoxication with CCl4 increased (P < 0.05) serum activities of alkaline phosphatase, gamma-GTP and ALT, and bilirubin concentration; liver collagen and lipoperoxidation were also increased. ...
Male Wistar rats were used: animals in group 1 received CCl4 (0.04 g per 100 g, i.p.) three times a week for 8 weeks; group 2 was tre …
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