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Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase.
Murillas R, Simms KS, Hatakeyama S, Weissman AM, Kuehn MR. Murillas R, et al. J Biol Chem. 2002 Jan 25;277(4):2897-907. doi: 10.1074/jbc.M110047200. Epub 2001 Nov 20. J Biol Chem. 2002. PMID: 11717310
N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies.
Sharma P, Murillas R, Zhang H, Kuehn MR. Sharma P, et al. Among authors: murillas r. J Cell Sci. 2010 Apr 15;123(Pt 8):1227-34. doi: 10.1242/jcs.060160. Epub 2010 Mar 16. J Cell Sci. 2010. PMID: 20233849 Free PMC article.
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
Oberst A, Malatesta M, Aqeilan RI, Rossi M, Salomoni P, Murillas R, Sharma P, Kuehn MR, Oren M, Croce CM, Bernassola F, Melino G. Oberst A, et al. Among authors: murillas r. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11280-5. doi: 10.1073/pnas.0701773104. Epub 2007 Jun 25. Proc Natl Acad Sci U S A. 2007. PMID: 17592138 Free PMC article.
Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia.
Robles AI, Larcher F, Whalin RB, Murillas R, Richie E, Gimenez-Conti IB, Jorcano JL, Conti CJ. Robles AI, et al. Among authors: murillas r. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7634-8. doi: 10.1073/pnas.93.15.7634. Proc Natl Acad Sci U S A. 1996. PMID: 8755527 Free PMC article.
Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.
Murillas R, Larcher F, Conti CJ, Santos M, Ullrich A, Jorcano JL. Murillas R, et al. EMBO J. 1995 Nov 1;14(21):5216-23. EMBO J. 1995. PMID: 7489711 Free PMC article.
Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways.
Cataisson C, Joseloff E, Murillas R, Wang A, Atwell C, Torgerson S, Gerdes M, Subleski J, Gao JL, Murphy PM, Wiltrout RH, Vinson C, Yuspa SH. Cataisson C, et al. Among authors: murillas r. J Immunol. 2003 Sep 1;171(5):2703-13. doi: 10.4049/jimmunol.171.5.2703. J Immunol. 2003. PMID: 12928424
Development of a bioengineered skin-humanized mouse model for psoriasis: dissecting epidermal-lymphocyte interacting pathways.
Guerrero-Aspizua S, García M, Murillas R, Retamosa L, Illera N, Duarte B, Holguín A, Puig S, Hernández MI, Meana A, Jorcano JL, Larcher F, Carretero M, Del Río M. Guerrero-Aspizua S, et al. Among authors: murillas r. Am J Pathol. 2010 Dec;177(6):3112-24. doi: 10.2353/ajpath.2010.100078. Epub 2010 Oct 22. Am J Pathol. 2010. PMID: 20971736 Free PMC article.
A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.
Casanova ML, Larcher F, Casanova B, Murillas R, Fernández-Aceñero MJ, Villanueva C, Martínez-Palacio J, Ullrich A, Conti CJ, Jorcano JL. Casanova ML, et al. Among authors: murillas r. Cancer Res. 2002 Jun 15;62(12):3402-7. Cancer Res. 2002. PMID: 12067982
Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.
Larcher F, Dellambra E, Rico L, Bondanza S, Murillas R, Cattoglio C, Mavilio F, Jorcano JL, Zambruno G, Del Rio M. Larcher F, et al. Among authors: murillas r. Mol Ther. 2007 Sep;15(9):1670-6. doi: 10.1038/ Epub 2007 Jun 19. Mol Ther. 2007. PMID: 17579576
RNAi-mediated knockdown of IKK1 in transgenic mice using a transgenic construct containing the human H1 promoter.
Moreno-Maldonado R, Murillas R, Navarro M, Page A, Suarez-Cabrera C, Alameda JP, Bravo A, Casanova ML, Ramirez A. Moreno-Maldonado R, et al. Among authors: murillas r. ScientificWorldJournal. 2014 Jan 12;2014:193803. doi: 10.1155/2014/193803. eCollection 2014. ScientificWorldJournal. 2014. PMID: 24523631 Free PMC article.
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