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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1989 1
1991 1
1992 2
1996 1
1997 1
1998 1
2000 2
2001 4
2002 2
2003 2
2005 2
2006 3
2007 3
2008 3
2011 1
2012 6
2013 7
2014 4
2015 5
2016 3
2017 3
2018 1
2019 2
2020 1
2021 0
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58 results
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Page 1
Genetic Dilated Cardiomyopathy Due to TTN Variants Without Known Familial Disease.
Brown EE, Murray B, Vaishnav J, Tampakakis E, Barouch LA, James C, Murphy AM, Judge DP. Brown EE, et al. Among authors: murphy am. Circ Genom Precis Med. 2020 Dec;13(6):e003082. doi: 10.1161/CIRCGEN.120.003082. Epub 2020 Nov 15. Circ Genom Precis Med. 2020. PMID: 33190517 No abstract available.
Baseline Characteristics of the VANISH Cohort.
Axelsson Raja A, Shi L, Day SM, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall EK, Becker J, Jefferies JL, Patel AR, Choudhury L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheeler MT, Benson L, Owens AT, Rossano J, Lin KY, Pahl E, Pereira AC, Bundgaard H, Lewis GD, Vargas JD, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY. Axelsson Raja A, et al. Among authors: murphy am. Circ Heart Fail. 2019 Dec;12(12):e006231. doi: 10.1161/CIRCHEARTFAILURE.119.006231. Epub 2019 Dec 9. Circ Heart Fail. 2019. PMID: 31813281 Free PMC article. Clinical Trial.
BACKGROUND: The VANISH trial (Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy) targeted young sarcomeric gene mutation carriers with early-stage hypertrophic cardiomyopathy (HCM) to test whether valsartan can modify disease
BACKGROUND: The VANISH trial (Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy) targeted y …
Genetic aetiologies should be considered in paediatric cases of acute heart failure presumed to be myocarditis.
Brown EE, McMilllan KN, Halushka MK, Ravekes WJ, Knight M, Crosson JE, Judge DP, Murphy AM. Brown EE, et al. Among authors: murphy am. Cardiol Young. 2019 Jul;29(7):917-921. doi: 10.1017/S1047951119001124. Epub 2019 Jun 14. Cardiol Young. 2019. PMID: 31198128
There are a variety of causes of acute heart failure in children including myocarditis, genetic/metabolic conditions, and congenital heart defects. In cases with a structurally normal heart and a negative personal and family history, myocarditis is often pres …
There are a variety of causes of acute heart failure in children including myocarditis, genetic/metabolic conditions, and congenital …
Prevalence and Progression of Late Gadolinium Enhancement in Children and Adolescents With Hypertrophic Cardiomyopathy.
Axelsson Raja A, Farhad H, Valente AM, Couce JP, Jefferies JL, Bundgaard H, Zahka K, Lever H, Murphy AM, Ashley E, Day SM, Sherrid MV, Shi L, Bluemke DA, Canter CE, Colan SD, Ho CY. Axelsson Raja A, et al. Among authors: murphy am. Circulation. 2018 Aug 21;138(8):782-792. doi: 10.1161/CIRCULATIONAHA.117.032966. Circulation. 2018. PMID: 29622585 Free PMC article.
In the subset of patients with serial imaging, statistically significant increases in LGE, LV mass, and left atrial size were detected over 2.5 years, indicating disease progression over time. Further prospective studies are required to confirm these findings and to better …
In the subset of patients with serial imaging, statistically significant increases in LGE, LV mass, and left atrial size were detected over …
Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.
Li Y, Zhu G, Paolocci N, Zhang P, Takahashi C, Okumus N, Heravi A, Keceli G, Ramirez-Correa G, Kass DA, Murphy AM. Li Y, et al. Among authors: murphy am. Circ Heart Fail. 2017 Sep;10(9):e003850. doi: 10.1161/CIRCHEARTFAILURE.117.003850. Circ Heart Fail. 2017. PMID: 28899987 Free PMC article.
CONCLUSIONS: Hyperphosphorylation of this serine in cTnI C terminus impacts heart function by depressing diastolic function at baseline and limiting systolic reserve under physiological stresses. However, paradoxically, it preserves heart function after ischemia/rep …
CONCLUSIONS: Hyperphosphorylation of this serine in cTnI C terminus impacts heart function by depressing diastolic function at baseli …
The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association.
Musunuru K, Ingelsson E, Fornage M, Liu P, Murphy AM, Newby LK, Newton-Cheh C, Perez MV, Voora D, Woo D; American Heart Association Committee on Molecular Determinants of Cardiovascular Health of the Council on Functional Genomics and Translational Biology and Council on Epidemiology and Prevention; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; and Stroke Council. Musunuru K, et al. Among authors: murphy am. Circ Cardiovasc Genet. 2017 Aug;10(4):e000037. doi: 10.1161/HCG.0000000000000037. Circ Cardiovasc Genet. 2017. PMID: 28760750 Review.
There have been major advances in our knowledge of the contribution of DNA sequence variations to cardiovascular disease and stroke. However, the inner workings of the body reflect the complex interplay of factors beyond the DNA sequence, including epigenetic modifications …
There have been major advances in our knowledge of the contribution of DNA sequence variations to cardiovascular disease and stroke. …
The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.
Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ; HCMNet Investigators. Ho CY, et al. Among authors: murphy am. JAMA Cardiol. 2017 Apr 1;2(4):419-428. doi: 10.1001/jamacardio.2016.5670. JAMA Cardiol. 2017. PMID: 28241245 Free PMC article.
However, little is known about the full spectrum of phenotypic manifestations or how LVH influences disease expression. OBJECTIVES: (1) To characterize and assess phenotypic burden in sarcomere mutation carriers (genotype positive [G+]) and (2) to investigate the correlati …
However, little is known about the full spectrum of phenotypic manifestations or how LVH influences disease expression. OBJECTIVES: ( …
Comprehensive Versus Targeted Genetic Testing in Children with Hypertrophic Cardiomyopathy.
Bales ND, Johnson NM, Judge DP, Murphy AM. Bales ND, et al. Among authors: murphy am. Pediatr Cardiol. 2016 Jun;37(5):845-51. doi: 10.1007/s00246-016-1358-y. Epub 2016 Mar 2. Pediatr Cardiol. 2016. PMID: 26936621 Free PMC article.
Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere that can be found in both children and adults and is associated with many causative mutations. ...
Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere that can be found in both children and adults and is associat …
Transplantation and Mechanical Circulatory Support in Congenital Heart Disease: A Scientific Statement From the American Heart Association.
Ross HJ, Law Y, Book WM, Broberg CS, Burchill L, Cecchin F, Chen JM, Delgado D, Dimopoulos K, Everitt MD, Gatzoulis M, Harris L, Hsu DT, Kuvin JT, Martin CM, Murphy AM, Singh G, Spray TL, Stout KK; American Heart Association Adults With Congenital Heart Disease Committee of the Council on Clinical Cardiology and Council on Cardiovascular Disease in the Young, the Council on Cardiovascular Radiology and Intervention, and the Council on Functional Genomics and Translational Biology. Ross HJ, et al. Among authors: murphy am. Circulation. 2016 Feb 23;133(8):802-20. doi: 10.1161/CIR.0000000000000353. Epub 2016 Jan 21. Circulation. 2016. PMID: 26797468 Free article. Review. No abstract available.
Chronic Heart Failure in Congenital Heart Disease: A Scientific Statement From the American Heart Association.
Stout KK, Broberg CS, Book WM, Cecchin F, Chen JM, Dimopoulos K, Everitt MD, Gatzoulis M, Harris L, Hsu DT, Kuvin JT, Law Y, Martin CM, Murphy AM, Ross HJ, Singh G, Spray TL; American Heart Association Council on Clinical Cardiology, Council on Functional Genomics and Translational Biology, and Council on Cardiovascular Radiology and Imaging. Stout KK, et al. Among authors: murphy am. Circulation. 2016 Feb 23;133(8):770-801. doi: 10.1161/CIR.0000000000000352. Epub 2016 Jan 19. Circulation. 2016. PMID: 26787728 Free article. Review. No abstract available.
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