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Quality of life following concurrent temozolomide-based chemoradiation therapy or observation in low-grade glioma.
Park DY, Tom MC, Wei W, Tewari S, Ahluwalia MS, Yu JS, Chao ST, Suh JH, Peereboom D, Stevens GHJ, Barnett GH, Angelov L, Mohammadi AM, Hogan T, Kissel C, Lapin B, Schuermeyer I, Parsons MW, Naugle R, Murphy ES. Park DY, et al. Among authors: murphy es. J Neurooncol. 2022 Feb;156(3):499-507. doi: 10.1007/s11060-021-03920-6. Epub 2022 Jan 22. J Neurooncol. 2022. PMID: 35064450
No significant decline was seen in EQ-5D or PHQ-9 scores at 3, 6, 9, 12, and 24 months compared to baseline scores for all patients. ...The linear mixed model estimating PHQ-9 value or EQ-5D index demonstrated that there was no significant difference in PHQ-9 or EQ- …
No significant decline was seen in EQ-5D or PHQ-9 scores at 3, 6, 9, 12, and 24 months compared to baseline scores for all patients. …
Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice.
VanderVeen BN, Cardaci TD, McDonald SJ, Madero SS, Unger CA, Bullard BM, Enos RT, Velázquez KT, Kubinak JL, Fan D, Murphy EA. VanderVeen BN, et al. Among authors: murphy ea. Cancer Biol Ther. 2022 Dec 31;23(1):1-15. doi: 10.1080/15384047.2022.2108306. Cancer Biol Ther. 2022. PMID: 35968771 Free PMC article.
C56BL/6 mice were given high fat (Obese) or standard diets (Lean) for 4 months and then subjected to three cycles of 5FU (5d-40 mg/kg Lean Mass, 9d rest) or PBS vehicle control. Shockingly, only 60% of Obese survived 3 cycles compared to 100% of Lean, and Obese lost signif …
C56BL/6 mice were given high fat (Obese) or standard diets (Lean) for 4 months and then subjected to three cycles of 5FU (5d-40 mg/kg …
Stereotactic Radiosurgery for Trigeminal Neuralgia Improves Patient-Reported Quality of Life and Reduces Depression.
Kotecha R, Miller JA, Modugula S, Barnett GH, Murphy ES, Reddy CA, Suh JH, Neyman G, Machado A, Nagel S, Chao ST. Kotecha R, et al. Among authors: murphy es. Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1078-1086. doi: 10.1016/j.ijrobp.2017.04.008. Epub 2017 Apr 11. Int J Radiat Oncol Biol Phys. 2017. PMID: 28721891
The Kaplan-Meier method was used to estimate time-dependent improvements in the EQ-5D index, EQ-5D perceived health status (PHS), PHQ-9 score, and freedom from pain failure (BNI class IV-V) or facial numbness (BNI class III-IV). ...In this analysis, there appears to …
The Kaplan-Meier method was used to estimate time-dependent improvements in the EQ-5D index, EQ-5D perceived health status (PH …
Toward Electrical Impedance Tomography Coupled Ultrasound Imaging for Assessing Muscle Health.
Murphy EK, Skinner J, Martucci M, Rutkove SB, Halter RJ. Murphy EK, et al. IEEE Trans Med Imaging. 2019 Jun;38(6):1409-1419. doi: 10.1109/TMI.2018.2886152. Epub 2018 Dec 10. IEEE Trans Med Imaging. 2019. PMID: 30530320 Free PMC article.
The US/EIT system represents a potential enhancement to electrical impedance myography (EIM), which has shown promise as a non-invasive technology that may have important clinical use in indicating neuromuscular disease status and as a diagnostic tool. A 2.5D EIT algorithm …
The US/EIT system represents a potential enhancement to electrical impedance myography (EIM), which has shown promise as a non-invasive tech …
Elucidating electrochemical nitrate and nitrite reduction over atomically-dispersed transition metal sites.
Murphy E, Liu Y, Matanovic I, Rüscher M, Huang Y, Ly A, Guo S, Zang W, Yan X, Martini A, Timoshenko J, Cuenya BR, Zenyuk IV, Pan X, Spoerke ED, Atanassov P. Murphy E, et al. Nat Commun. 2023 Jul 28;14(1):4554. doi: 10.1038/s41467-023-40174-4. Nat Commun. 2023. PMID: 37507382 Free PMC article.
Herein, we report a set of 14; 3d-, 4d-, 5d- and f-block M-N-C catalysts. The selectivity and activity of NO(3)(-) reduction to NH(3) in neutral media, with a specific focus on deciphering the role of the NO(2)(-) intermediate in the reaction cascade, reveals strong correl …
Herein, we report a set of 14; 3d-, 4d-, 5d- and f-block M-N-C catalysts. The selectivity and activity of NO(3)(-) reduction to NH(3) …
Quality of Life following Stereotactic Radiosurgery for Single and Multiple Brain Metastases.
Miller JA, Kotecha R, Barnett GH, Suh JH, Angelov L, Murphy ES, Vogelbaum MA, Mohammadi A, Chao ST. Miller JA, et al. Among authors: murphy es. Neurosurgery. 2017 Jul 1;81(1):147-155. doi: 10.1093/neuros/nyw166. Neurosurgery. 2017. PMID: 28327994
METHODS: The EuroQol 5 Dimensions questionnaire (EQ-5D) and Patient Health Questionnaire 9 instruments were prospectively collected from a cohort of patients undergoing SRS for brain metastasis between 2008 and 2015. ...QOL deterioration exceeding the minimum clinically im …
METHODS: The EuroQol 5 Dimensions questionnaire (EQ-5D) and Patient Health Questionnaire 9 instruments were prospectively collected f …
A novel approach using 3-D printing in the Irish National Centre for pelvic and acetabular surgery.
Downey C, McCarrick C, Fenelon C, Murphy EP, O'Daly BJ, Leonard M. Downey C, et al. Among authors: murphy ep. Ir J Med Sci. 2020 Feb;189(1):219-228. doi: 10.1007/s11845-019-02055-y. Epub 2019 Jul 6. Ir J Med Sci. 2020. PMID: 31280418
OUTCOME MEASURES: Classification assistance, intra-operative time, estimated blood loss, screening amount, post-operative reduction and infection, EQ-5D-5L, teaching/educational assistance and pre-operative counselling. RESULTS: The models provided more information regardi …
OUTCOME MEASURES: Classification assistance, intra-operative time, estimated blood loss, screening amount, post-operative reduction and infe …
The VIVID trial 12-month outcomes of the venous stent for the iliofemoral vein using the Duo venous stent system.
Razavi M, Lichtenberg M, Desai K, Dexter D, Soukas P, Shammas N, Lodha A, Gagne P, Nordell A, Kolluri R, Garcia M; VIVID Trial Investigators. Razavi M, et al. J Vasc Surg Venous Lymphat Disord. 2024 Oct 29:101995. doi: 10.1016/j.jvsv.2024.101995. Online ahead of print. J Vasc Surg Venous Lymphat Disord. 2024. PMID: 39477150 Free article.
Patient-reported outcomes showed improvements in Venous Clinical Severity Score, Villalta, EQ-5D-3 L, and VEINES-QoL/Sym scores from baseline through 6 and 12 months. CONCLUSIONS: Through 12 months, the Duo Venous Stent System is safe and effective for the treatment of non …
Patient-reported outcomes showed improvements in Venous Clinical Severity Score, Villalta, EQ-5D-3 L, and VEINES-QoL/Sym scores from …
A growing problem: cycling referrals to the National Centre for Pelvic and Acetabular Fracture Management in Ireland.
Fenelon C, Murphy EP, Downey C, O'Daly BJ, Leonard M. Fenelon C, et al. Among authors: murphy ep. Ir J Med Sci. 2019 Aug;188(3):855-859. doi: 10.1007/s11845-018-1926-7. Epub 2018 Nov 11. Ir J Med Sci. 2019. PMID: 30417243
Patients were contacted to assess return to work, sport and quality of life (EQ-5D-3L). RESULTS: Cycling injury referrals increased by 90% between 2016 and 2017 with a greater number of cycling than motorbike injury referrals. ...
Patients were contacted to assess return to work, sport and quality of life (EQ-5D-3L). RESULTS: Cycling injury referrals increased b …