Murphy CT - Search Results

1

An integrative tissue-network approach to identify and test human disease genes.

Yao V, Kaletsky R, Keyes W, Mor DE, Wong AK, Sohrabi S, Murphy CT, Troyanskaya OG. Yao V, et al. Among authors: murphy ct. Nat Biotechnol. 2018 Oct 22:10.1038/nbt.4246. doi: 10.1038/nbt.4246. Online ahead of print. Nat Biotechnol. 2018. PMID: 30346941 Free PMC article.

2

Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.

Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG. Chikina MD, et al. Among authors: murphy ct. PLoS Comput Biol. 2009 Jun;5(6):e1000417. doi: 10.1371/journal.pcbi.1000417. Epub 2009 Jun 19. PLoS Comput Biol. 2009. PMID: 19543383 Free PMC article.

3

The role of insulin/IGF-like signaling in C. elegans longevity and aging.

Kaletsky R, Murphy CT. Kaletsky R, et al. Among authors: murphy ct. Dis Model Mech. 2010 Jul-Aug;3(7-8):415-9. doi: 10.1242/dmm.001040. Epub 2010 Mar 30. Dis Model Mech. 2010. PMID: 20354111 Free article. Review.

4

C. elegans positive butanone learning, short-term, and long-term associative memory assays.

Kauffman A, Parsons L, Stein G, Wills A, Kaletsky R, Murphy C. Kauffman A, et al. J Vis Exp. 2011 Mar 11;(49):2490. doi: 10.3791/2490. J Vis Exp. 2011. PMID: 21445035 Free PMC article.

5

PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.

Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ. Tepper RG, et al. Among authors: murphy ct. Cell. 2013 Aug 1;154(3):676-690. doi: 10.1016/j.cell.2013.07.006. Cell. 2013. PMID: 23911329 Free PMC article.

6

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. Fernandes de Abreu DA, et al. Among authors: murphy ct. PLoS Genet. 2014 Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24675767 Free PMC article.

7

Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.

Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT. Lakhina V, et al. Among authors: murphy ct. Neuron. 2015 Jan 21;85(2):330-45. doi: 10.1016/j.neuron.2014.12.029. Neuron. 2015. PMID: 25611510 Free PMC article.

8

The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators.

Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy CT. Kaletsky R, et al. Among authors: murphy ct. Nature. 2016 Jan 7;529(7584):92-6. doi: 10.1038/nature16483. Epub 2015 Dec 14. Nature. 2016. PMID: 26675724 Free PMC article.

9

Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis.

Wang J, Kaletsky R, Silva M, Williams A, Haas LA, Androwski RJ, Landis JN, Patrick C, Rashid A, Santiago-Martinez D, Gravato-Nobre M, Hodgkin J, Hall DH, Murphy CT, Barr MM. Wang J, et al. Among authors: murphy ct. Curr Biol. 2015 Dec 21;25(24):3232-8. doi: 10.1016/j.cub.2015.10.057. Epub 2015 Dec 10. Curr Biol. 2015. PMID: 26687621 Free PMC article.

10

RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans.

Son HG, Seo M, Ham S, Hwang W, Lee D, An SW, Artan M, Seo K, Kaletsky R, Arey RN, Ryu Y, Ha CM, Kim YK, Murphy CT, Roh TY, Nam HG, Lee SV. Son HG, et al. Among authors: murphy ct. Nat Commun. 2017 Mar 9;8:14749. doi: 10.1038/ncomms14749. Nat Commun. 2017. PMID: 28276441 Free PMC article.

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