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Hypoxia Controls the Glycome Signature and Galectin-8-Ligand Axis to Promote Protumorigenic Properties of Metastatic Melanoma.
Chakraborty A, Perez M, Carroll JD, Antonopoulos A, Dell A, Ortega L, Mohammed NBB, Wells M, Staudinger C, Griswold A, Chandler KB, Marrero C, Jimenez R, Tani Y, Wilmott JS, Thompson JF, Wang W, Sackstein R, Scolyer RA, Murphy GF, Haslam SM, Dimitroff CJ. Chakraborty A, et al. Among authors: murphy gf. J Invest Dermatol. 2023 Mar;143(3):456-469.e8. doi: 10.1016/j.jid.2022.07.033. Epub 2022 Sep 27. J Invest Dermatol. 2023. PMID: 36174713 Free PMC article.
Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity.
Cedeno-Laurent F, Opperman MJ, Barthel SR, Hays D, Schatton T, Zhan Q, He X, Matta KL, Supko JG, Frank MH, Murphy GF, Dimitroff CJ. Cedeno-Laurent F, et al. Among authors: murphy gf. J Invest Dermatol. 2012 Feb;132(2):410-20. doi: 10.1038/jid.2011.335. Epub 2011 Dec 8. J Invest Dermatol. 2012. PMID: 22158550 Free PMC article.
Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential.
Yazawa EM, Geddes-Sweeney JE, Cedeno-Laurent F, Walley KC, Barthel SR, Opperman MJ, Liang J, Lin JY, Schatton T, Laga AC, Mihm MC, Qureshi AA, Widlund HR, Murphy GF, Dimitroff CJ. Yazawa EM, et al. Among authors: murphy gf. J Invest Dermatol. 2015 Jul;135(7):1849-1862. doi: 10.1038/jid.2015.95. Epub 2015 Mar 10. J Invest Dermatol. 2015. PMID: 25756799 Free PMC article.
Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.
Sweeney JG, Liang J, Antonopoulos A, Giovannone N, Kang S, Mondala TS, Head SR, King SL, Tani Y, Brackett D, Dell A, Murphy GF, Haslam SM, Widlund HR, Dimitroff CJ. Sweeney JG, et al. Among authors: murphy gf. Nat Commun. 2018 Aug 22;9(1):3368. doi: 10.1038/s41467-018-05795-0. Nat Commun. 2018. PMID: 30135430 Free PMC article.
SOX2 contributes to melanoma cell invasion.
Girouard SD, Laga AC, Mihm MC, Scolyer RA, Thompson JF, Zhan Q, Widlund HR, Lee CW, Murphy GF. Girouard SD, et al. Among authors: murphy gf. Lab Invest. 2012 Mar;92(3):362-70. doi: 10.1038/labinvest.2011.188. Epub 2011 Dec 19. Lab Invest. 2012. PMID: 22184093 Free PMC article.
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG. Lian CG, et al. Among authors: murphy gf. Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033. Cell. 2012. PMID: 22980977 Free PMC article.
410 results