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Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma.
Young PW, Buckle DR, Cantello BC, Chapman H, Clapham JC, Coyle PJ, Haigh D, Hindley RM, Holder JC, Kallender H, Latter AJ, Lawrie KW, Mossakowska D, Murphy GJ, Roxbee Cox L, Smith SA. Young PW, et al. Among authors: murphy gj. J Pharmacol Exp Ther. 1998 Feb;284(2):751-9. J Pharmacol Exp Ther. 1998. PMID: 9454824
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.
Coghlan MP, Culbert AA, Cross DA, Corcoran SL, Yates JW, Pearce NJ, Rausch OL, Murphy GJ, Carter PS, Roxbee Cox L, Mills D, Brown MJ, Haigh D, Ward RW, Smith DG, Murray KJ, Reith AD, Holder JC. Coghlan MP, et al. Among authors: murphy gj. Chem Biol. 2000 Oct;7(10):793-803. doi: 10.1016/s1074-5521(00)00025-9. Chem Biol. 2000. PMID: 11033082
v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle-associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker diabetic fatty rats.
Maier VH, Melvin DR, Lister CA, Chapman H, Gould GW, Murphy GJ. Maier VH, et al. Among authors: murphy gj. Diabetes. 2000 Apr;49(4):618-25. doi: 10.2337/diabetes.49.4.618. Diabetes. 2000. PMID: 10871200
The tissue distribution of the human beta3-adrenoceptor studied using a monoclonal antibody: direct evidence of the beta3-adrenoceptor in human adipose tissue, atrium and skeletal muscle.
Chamberlain PD, Jennings KH, Paul F, Cordell J, Berry A, Holmes SD, Park J, Chambers J, Sennitt MV, Stock MJ, Cawthorne MA, Young PW, Murphy GJ. Chamberlain PD, et al. Among authors: murphy gj. Int J Obes Relat Metab Disord. 1999 Oct;23(10):1057-65. doi: 10.1038/sj.ijo.0801039. Int J Obes Relat Metab Disord. 1999. PMID: 10557026
293 results