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From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce T(H)1 development.
O'Garra A, Murphy KM. O'Garra A, et al. Among authors: murphy km. Nat Immunol. 2009 Sep;10(9):929-32. doi: 10.1038/ni0909-929. Nat Immunol. 2009. PMID: 19692989 Review.
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.
Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA, Wysocka M, Trinchieri G, Murphy KM, O'Garra A. Macatonia SE, et al. Among authors: murphy km. J Immunol. 1995 May 15;154(10):5071-9. J Immunol. 1995. PMID: 7730613
Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent.
Macatonia SE, Hsieh CS, Murphy KM, O'Garra A. Macatonia SE, et al. Among authors: murphy km. Int Immunol. 1993 Sep;5(9):1119-28. doi: 10.1093/intimm/5.9.1119. Int Immunol. 1993. PMID: 7902129
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages.
Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM. Hsieh CS, et al. Among authors: murphy km. Science. 1993 Apr 23;260(5107):547-9. doi: 10.1126/science.8097338. Science. 1993. PMID: 8097338
Pathogen-induced Th1 phenotype development in CD4+ alpha beta-TCR transgenic T cells is macrophage dependent.
Hsieh CS, Macatonia SE, O'Garra A, Murphy KM. Hsieh CS, et al. Among authors: murphy km. Int Immunol. 1993 Apr;5(4):371-82. doi: 10.1093/intimm/5.4.371. Int Immunol. 1993. PMID: 8494824
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development.
Wenner CA, Güler ML, Macatonia SE, O'Garra A, Murphy KM. Wenner CA, et al. Among authors: murphy km. J Immunol. 1996 Feb 15;156(4):1442-7. J Immunol. 1996. PMID: 8568246
Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development.
Güler ML, Gorham JD, Hsieh CS, Mackey AJ, Steen RG, Dietrich WF, Murphy KM. Güler ML, et al. Among authors: murphy km. Science. 1996 Feb 16;271(5251):984-7. doi: 10.1126/science.271.5251.984. Science. 1996. PMID: 8584935
Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development.
Wenner CA, Szabo SJ, Murphy KM. Wenner CA, et al. Among authors: murphy km. J Immunol. 1997 Jan 15;158(2):765-73. J Immunol. 1997. PMID: 8992993
T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development.
Güler ML, Jacobson NG, Gubler U, Murphy KM. Güler ML, et al. Among authors: murphy km. J Immunol. 1997 Aug 15;159(4):1767-74. J Immunol. 1997. PMID: 9257839
Regulation of IL-12 receptor expression in early T-helper responses implies two phases of Th1 differentiation: capacitance and development.
Murphy KM, Murphy TL, Szabo SJ, Jacobson NG, Guler ML, Gorham JD, Gubler U. Murphy KM, et al. Among authors: murphy tl. Chem Immunol. 1997;68:54-69. doi: 10.1159/000058694. Chem Immunol. 1997. PMID: 9329216 Review. No abstract available.
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