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UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction.
Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. Kazak L, et al. Among authors: murphy mp. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):7981-7986. doi: 10.1073/pnas.1705406114. Epub 2017 Jun 19. Proc Natl Acad Sci U S A. 2017. PMID: 28630339 Free PMC article.
Delivery of bioactive molecules to mitochondria in vivo.
Smith RA, Porteous CM, Gane AM, Murphy MP. Smith RA, et al. Among authors: murphy mp. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5407-12. doi: 10.1073/pnas.0931245100. Epub 2003 Apr 15. Proc Natl Acad Sci U S A. 2003. PMID: 12697897 Free PMC article.
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP. Prime TA, et al. Among authors: murphy mp. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15. Proc Natl Acad Sci U S A. 2009. PMID: 19528654 Free PMC article.
Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation.
Chouchani ET, Hurd TR, Nadtochiy SM, Brookes PS, Fearnley IM, Lilley KS, Smith RA, Murphy MP. Chouchani ET, et al. Among authors: murphy mp. Biochem J. 2010 Aug 15;430(1):49-59. doi: 10.1042/BJ20100633. Biochem J. 2010. PMID: 20533907 Free PMC article.
Measuring mitochondrial protein thiol redox state.
Requejo R, Chouchani ET, Hurd TR, Menger KE, Hampton MB, Murphy MP. Requejo R, et al. Among authors: murphy mp. Methods Enzymol. 2010;474:123-47. doi: 10.1016/S0076-6879(10)74008-8. Epub 2010 Jun 20. Methods Enzymol. 2010. PMID: 20609908
Proteomic approaches to the characterization of protein thiol modification.
Chouchani ET, James AM, Fearnley IM, Lilley KS, Murphy MP. Chouchani ET, et al. Among authors: murphy mp. Curr Opin Chem Biol. 2011 Feb;15(1):120-8. doi: 10.1016/j.cbpa.2010.11.003. Epub 2010 Dec 2. Curr Opin Chem Biol. 2011. PMID: 21130020 Free PMC article. Review.
Mitochondrial redox signalling at a glance.
Collins Y, Chouchani ET, James AM, Menger KE, Cochemé HM, Murphy MP. Collins Y, et al. Among authors: murphy mp. J Cell Sci. 2012 Feb 15;125(Pt 4):801-6. doi: 10.1242/jcs.098475. J Cell Sci. 2012. PMID: 22448036 No abstract available.
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.
Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, Krieg T, Brookes PS, Murphy MP. Chouchani ET, et al. Among authors: murphy mp. Nat Med. 2013 Jun;19(6):753-9. doi: 10.1038/nm.3212. Epub 2013 May 26. Nat Med. 2013. PMID: 23708290 Free PMC article.
786 results