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Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury.
Kohlhauer M, Dawkins S, Costa ASH, Lee R, Young T, Pell VR, Choudhury RP, Banning AP, Kharbanda RK; Oxford Acute Myocardial Infarction (OxAMI) Study; Saeb-Parsy K, Murphy MP, Frezza C, Krieg T, Channon KM. Kohlhauer M, et al. Among authors: murphy mp. J Am Heart Assoc. 2018 Apr 6;7(8):e007546. doi: 10.1161/JAHA.117.007546. J Am Heart Assoc. 2018. PMID: 29626151 Free PMC article.
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.
Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, Krieg T, Brookes PS, Murphy MP. Chouchani ET, et al. Among authors: murphy mp. Nat Med. 2013 Jun;19(6):753-9. doi: 10.1038/nm.3212. Epub 2013 May 26. Nat Med. 2013. PMID: 23708290 Free PMC article.
Using exomarkers to assess mitochondrial reactive species in vivo.
Logan A, Cochemé HM, Li Pun PB, Apostolova N, Smith RA, Larsen L, Larsen DS, James AM, Fearnley IM, Rogatti S, Prime TA, Finichiu PG, Dare A, Chouchani ET, Pell VR, Methner C, Quin C, McQuaker SJ, Krieg T, Hartley RC, Murphy MP. Logan A, et al. Among authors: murphy mp. Biochim Biophys Acta. 2014 Feb;1840(2):923-30. doi: 10.1016/j.bbagen.2013.05.026. Epub 2013 May 30. Biochim Biophys Acta. 2014. PMID: 23726990 Free article. Review.
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord ENJ, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, Rogatti S, Hartley RC, Eaton S, Costa ASH, Brookes PS, Davidson SM, Duchen MR, Saeb-Parsy K, Shattock MJ, Robinson AJ, Work LM, Frezza C, Krieg T, Murphy MP. Chouchani ET, et al. Among authors: murphy mp. Nature. 2014 Nov 20;515(7527):431-435. doi: 10.1038/nature13909. Epub 2014 Nov 5. Nature. 2014. PMID: 25383517 Free PMC article.
Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry.
Logan A, Pell VR, Shaffer KJ, Evans C, Stanley NJ, Robb EL, Prime TA, Chouchani ET, Cochemé HM, Fearnley IM, Vidoni S, James AM, Porteous CM, Partridge L, Krieg T, Smith RA, Murphy MP. Logan A, et al. Among authors: murphy mp. Cell Metab. 2016 Feb 9;23(2):379-85. doi: 10.1016/j.cmet.2015.11.014. Epub 2015 Dec 17. Cell Metab. 2016. PMID: 26712463 Free PMC article.
786 results