Murphy MW - Search Results

1

The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming.

Lindeman RE, Murphy MW, Agrimson KS, Gewiss RL, Bardwell VJ, Gearhart MD, Zarkower D. Lindeman RE, et al. Among authors: murphy mw. Nucleic Acids Res. 2021 Jun 21;49(11):6144-6164. doi: 10.1093/nar/gkab448. Nucleic Acids Res. 2021. PMID: 34096593 Free PMC article.

2

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures.

Rahmoun M, Lavery R, Laurent-Chaballier S, Bellora N, Philip GK, Rossitto M, Symon A, Pailhoux E, Cammas F, Chung J, Bagheri-Fam S, Murphy M, Bardwell V, Zarkower D, Boizet-Bonhoure B, Clair P, Harley VR, Poulat F. Rahmoun M, et al. Nucleic Acids Res. 2017 Jul 7;45(12):7191-7211. doi: 10.1093/nar/gkx328. Nucleic Acids Res. 2017. PMID: 28472341 Free PMC article.

3

DMRT1 prevents female reprogramming in the postnatal mammalian testis.

Matson CK, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ, Zarkower D. Matson CK, et al. Among authors: murphy mw. Nature. 2011 Jul 20;476(7358):101-4. doi: 10.1038/nature10239. Nature. 2011. PMID: 21775990 Free PMC article.

4

DMRT1: An Ancient Sexual Regulator Required for Human Gonadogenesis.

Zarkower D, Murphy MW. Zarkower D, et al. Among authors: murphy mw. Sex Dev. 2022;16(2-3):112-125. doi: 10.1159/000518272. Epub 2021 Sep 1. Sex Dev. 2022. PMID: 34515237 Free PMC article. Review.

5

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis.

Agrimson KS, Minkina A, Sadowski D, Wheeler A, Murphy MW, Gearhart MD, Bardwell VJ, Zarkower D. Agrimson KS, et al. Among authors: murphy mw. PLoS Genet. 2022 Feb 22;18(2):e1010088. doi: 10.1371/journal.pgen.1010088. eCollection 2022 Feb. PLoS Genet. 2022. PMID: 35192609 Free PMC article.

6

Genomics of sexual cell fate transdifferentiation in the mouse gonad.

Murphy MW, Gearhart MD, Wheeler A, Bardwell VJ, Zarkower D. Murphy MW, et al. G3 (Bethesda). 2022 Dec 1;12(12):jkac267. doi: 10.1093/g3journal/jkac267. G3 (Bethesda). 2022. PMID: 36200842 Free PMC article.

7

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA.

Murphy MW, Zarkower D, Bardwell VJ. Murphy MW, et al. BMC Mol Biol. 2007 Jul 2;8:58. doi: 10.1186/1471-2199-8-58. BMC Mol Biol. 2007. PMID: 17605809 Free PMC article.

8

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D. Krentz AD, et al. Among authors: murphy mw. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8. doi: 10.1073/pnas.0905431106. Epub 2009 Dec 10. Proc Natl Acad Sci U S A. 2009. PMID: 20007774 Free PMC article.

9

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis.

Murphy MW, Sarver AL, Rice D, Hatzi K, Ye K, Melnick A, Heckert LL, Zarkower D, Bardwell VJ. Murphy MW, et al. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13360-5. doi: 10.1073/pnas.1006243107. Epub 2010 Jul 7. Proc Natl Acad Sci U S A. 2010. PMID: 20616082 Free PMC article.

10

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.

Matson CK, Murphy MW, Griswold MD, Yoshida S, Bardwell VJ, Zarkower D. Matson CK, et al. Among authors: murphy mw. Dev Cell. 2010 Oct 19;19(4):612-24. doi: 10.1016/j.devcel.2010.09.010. Dev Cell. 2010. PMID: 20951351 Free PMC article.

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