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HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, Wrin T, Algate P, Chan-Hui PY, Karita E; IAVI Protocol C Investigators; IAVI African HIV Research Network; Ward AB, Wilson IA, Burton DR, Smith D, Pond SLK, Poignard P. Landais E, et al. Among authors: murrell s. Immunity. 2017 Nov 21;47(5):990-1003.e9. doi: 10.1016/j.immuni.2017.11.002. Immunity. 2017. PMID: 29166592 Free PMC article.
Gene-wide identification of episodic selection.
Murrell B, Weaver S, Smith MD, Wertheim JO, Murrell S, Aylward A, Eren K, Pollner T, Martin DP, Smith DM, Scheffler K, Kosakovsky Pond SL. Murrell B, et al. Among authors: murrell s. Mol Biol Evol. 2015 May;32(5):1365-71. doi: 10.1093/molbev/msv035. Epub 2015 Feb 19. Mol Biol Evol. 2015. PMID: 25701167 Free PMC article.
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE Jr. Willis JR, et al. Among authors: murrell s. J Clin Invest. 2015 Jun;125(6):2523-31. doi: 10.1172/JCI80693. Epub 2015 May 18. J Clin Invest. 2015. PMID: 25985274 Free PMC article.
Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Joyce C, Murrell S, Murrell B, Omorodion O, Ver LS, Carrico N, Bastidas R, Nedellec R, Bick M, Woehl J, Zhao F, Burns A, Barman S, Appel M, Ramos A, Wickramasinghe L, Eren K, Vollbrecht T, Smith DM, Kosakovsky Pond SL, McBride R, Worth C, Batista F, Sok D; IAVI Protocol C Investigators & The IAVI African HIV Research Network; Poignard P, Briney B, Wilson IA, Landais E, Burton DR. Joyce C, et al. Among authors: murrell s. PLoS Pathog. 2023 Jun 29;19(6):e1011416. doi: 10.1371/journal.ppat.1011416. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37384622 Free PMC article.
The genomes of many yam species contain transcriptionally active endogenous geminiviral sequences that may be functionally expressed.
Filloux D, Murrell S, Koohapitagtam M, Golden M, Julian C, Galzi S, Uzest M, Rodier-Goud M, D'Hont A, Vernerey MS, Wilkin P, Peterschmitt M, Winter S, Murrell B, Martin DP, Roumagnac P. Filloux D, et al. Among authors: murrell b, murrell s. Virus Evol. 2015 May 26;1(1):vev002. doi: 10.1093/ve/vev002. eCollection 2015. Virus Evol. 2015. PMID: 27774276 Free PMC article.
77 results