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The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD.
Bailey P, Sartorelli V, Hamamori Y, Muscat GE. Bailey P, et al. Among authors: muscat ge. Nucleic Acids Res. 1998 Dec 1;26(23):5501-10. doi: 10.1093/nar/26.23.5501. Nucleic Acids Res. 1998. PMID: 9826778 Free PMC article.
Transcriptional repression by COUP-TF II is dependent on the C-terminal domain and involves the N-CoR variant, RIP13delta1.
Bailey PJ, Dowhan DH, Franke K, Burke LJ, Downes M, Muscat GE. Bailey PJ, et al. Among authors: muscat ge. J Steroid Biochem Mol Biol. 1997 Nov-Dec;63(4-6):165-74. doi: 10.1016/s0960-0760(97)00079-4. J Steroid Biochem Mol Biol. 1997. PMID: 9459182
Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family.
Downes M, Carozzi AJ, Muscat GE. Downes M, et al. Among authors: muscat ge. Mol Endocrinol. 1995 Dec;9(12):1666-78. doi: 10.1210/mend.9.12.8614403. Mol Endocrinol. 1995. PMID: 8614403
Characterization of the thyroid hormone response element in the skeletal alpha-actin gene: negative regulation of T3 receptor binding by the retinoid X receptor.
Muscat GE, Griggs R, Downes M, Emery J. Muscat GE, et al. Cell Growth Differ. 1993 Apr;4(4):269-79. Cell Growth Differ. 1993. PMID: 8388243
Identification of a thyroid hormone response element in the mouse myogenin gene: characterization of the thyroid hormone and retinoid X receptor heterodimeric binding site.
Downes M, Griggs R, Atkins A, Olson EN, Muscat GE. Downes M, et al. Among authors: muscat ge. Cell Growth Differ. 1993 Nov;4(11):901-9. Cell Growth Differ. 1993. PMID: 8297796
Expression vectors encoding human growth hormone (hGH) controlled by human muscle-specific promoters: prospects for regulated production of hGH delivered by myoblast transfer or intravenous injection.
Dahler A, Wade RP, Muscat GE, Waters MJ. Dahler A, et al. Among authors: muscat ge. Gene. 1994 Aug 5;145(2):305-10. doi: 10.1016/0378-1119(94)90025-6. Gene. 1994. PMID: 8056348
Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesis.
Muscat GE, Rea S, Downes M. Muscat GE, et al. Nucleic Acids Res. 1995 Apr 25;23(8):1311-8. doi: 10.1093/nar/23.8.1311. Nucleic Acids Res. 1995. PMID: 7753622 Free PMC article.
Regulation of vertebrate muscle differentiation by thyroid hormone: the role of the myoD gene family.
Muscat GE, Downes M, Dowhan DH. Muscat GE, et al. Bioessays. 1995 Mar;17(3):211-8. doi: 10.1002/bies.950170307. Bioessays. 1995. PMID: 7748175 Review.
Proliferin, a prolactin/growth hormone-like peptide represses myogenic-specific transcription by the suppression of an essential serum response factor-like DNA-binding activity.
Muscat GE, Gobius K, Emery J. Muscat GE, et al. Mol Endocrinol. 1991 Jun;5(6):802-14. doi: 10.1210/mend-5-6-802. Mol Endocrinol. 1991. PMID: 1656242
The human skeletal alpha-actin promoter is regulated by thyroid hormone: identification of a thyroid hormone response element.
Collie ES, Muscat GE. Collie ES, et al. Among authors: muscat ge. Cell Growth Differ. 1992 Jan;3(1):31-42. Cell Growth Differ. 1992. PMID: 1318069
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