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Dissecting the logical types of network control in gene expression profiles.
Marr C, Geertz M, Hütt MT, Muskhelishvili G. Marr C, et al. Among authors: muskhelishvili g. BMC Syst Biol. 2008 Feb 19;2:18. doi: 10.1186/1752-0509-2-18. BMC Syst Biol. 2008. PMID: 18284674 Free PMC article.
RESULTS: Here we look at the properties of effective networks derived from significant gene expression changes under variation of the two forms of control and find that upon limitations of one type of control (caused e.g. by mutation of a global DNA architectural factor) t …
RESULTS: Here we look at the properties of effective networks derived from significant gene expression changes under variation of the two fo …
Isolation and Analysis of RNA Polymerase Supramolecular Complex with Associated Proteins.
Mehandziska S, Petrescu AM, Muskhelishvili G. Mehandziska S, et al. Among authors: muskhelishvili g. Methods Mol Biol. 2017;1624:101-116. doi: 10.1007/978-1-4939-7098-8_9. Methods Mol Biol. 2017. PMID: 28842879
Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization.
Japaridze A, Muskhelishvili G, Benedetti F, Gavriilidou AF, Zenobi R, De Los Rios P, Longo G, Dietler G. Japaridze A, et al. Among authors: muskhelishvili g. Nano Lett. 2017 Mar 8;17(3):1938-1948. doi: 10.1021/acs.nanolett.6b05294. Epub 2017 Feb 16. Nano Lett. 2017. PMID: 28191853
Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein.
Japaridze A, Renevey S, Sobetzko P, Stoliar L, Nasser W, Dietler G, Muskhelishvili G. Japaridze A, et al. Among authors: muskhelishvili g. J Biol Chem. 2017 May 5;292(18):7607-7618. doi: 10.1074/jbc.M117.780239. Epub 2017 Mar 18. J Biol Chem. 2017. PMID: 28316324 Free PMC article.
Upstream binding of idling RNA polymerase modulates transcription initiation from a nearby promoter.
Gerganova V, Maurer S, Stoliar L, Japaridze A, Dietler G, Nasser W, Kutateladze T, Travers A, Muskhelishvili G. Gerganova V, et al. Among authors: muskhelishvili g. J Biol Chem. 2015 Mar 27;290(13):8095-109. doi: 10.1074/jbc.M114.628131. Epub 2015 Feb 2. J Biol Chem. 2015. PMID: 25648898 Free PMC article.
Buffering of stable RNA promoter activity against DNA relaxation requires a far upstream sequence.
Rochman M, Blot N, Dyachenko M, Glaser G, Travers A, Muskhelishvili G. Rochman M, et al. Among authors: muskhelishvili g. Mol Microbiol. 2004 Jul;53(1):143-52. doi: 10.1111/j.1365-2958.2004.04126.x. Mol Microbiol. 2004. PMID: 15225310
High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes.
Lang B, Blot N, Bouffartigues E, Buckle M, Geertz M, Gualerzi CO, Mavathur R, Muskhelishvili G, Pon CL, Rimsky S, Stella S, Babu MM, Travers A. Lang B, et al. Among authors: muskhelishvili g. Nucleic Acids Res. 2007;35(18):6330-7. doi: 10.1093/nar/gkm712. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881364 Free PMC article.
Chromosomal position shift of a regulatory gene alters the bacterial phenotype.
Gerganova V, Berger M, Zaldastanishvili E, Sobetzko P, Lafon C, Mourez M, Travers A, Muskhelishvili G. Gerganova V, et al. Among authors: muskhelishvili g. Nucleic Acids Res. 2015 Sep 30;43(17):8215-26. doi: 10.1093/nar/gkv709. Epub 2015 Jul 13. Nucleic Acids Res. 2015. PMID: 26170236 Free PMC article.
Coordination of genomic structure and transcription by the main bacterial nucleoid-associated protein HU.
Berger M, Farcas A, Geertz M, Zhelyazkova P, Brix K, Travers A, Muskhelishvili G. Berger M, et al. Among authors: muskhelishvili g. EMBO Rep. 2010 Jan;11(1):59-64. doi: 10.1038/embor.2009.232. Epub 2009 Nov 13. EMBO Rep. 2010. PMID: 20010798 Free PMC article.
Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genome.
Blot N, Mavathur R, Geertz M, Travers A, Muskhelishvili G. Blot N, et al. Among authors: muskhelishvili g. EMBO Rep. 2006 Jul;7(7):710-5. doi: 10.1038/sj.embor.7400729. Epub 2006 Jun 16. EMBO Rep. 2006. PMID: 16799466 Free PMC article.
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