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Reactive rifampicin derivative able to damage transcription complex.
Kozlov M, Nudler E, Nikiforov V, Mustaev A. Kozlov M, et al. Among authors: mustaev a. Bioconjug Chem. 2013 Mar 20;24(3):443-7. doi: 10.1021/bc3005667. Epub 2013 Mar 1. Bioconjug Chem. 2013. PMID: 23425196
Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length.
Kuznedelov K, Korzheva N, Mustaev A, Severinov K. Kuznedelov K, et al. Among authors: mustaev a. EMBO J. 2002 Mar 15;21(6):1369-78. doi: 10.1093/emboj/21.6.1369. EMBO J. 2002. PMID: 11889042 Free PMC article.
Swing-gate model of nucleotide entry into the RNA polymerase active center.
Epshtein V, Mustaev A, Markovtsov V, Bereshchenko O, Nikiforov V, Goldfarb A. Epshtein V, et al. Among authors: mustaev a. Mol Cell. 2002 Sep;10(3):623-34. doi: 10.1016/s1097-2765(02)00640-8. Mol Cell. 2002. PMID: 12408829
Unified two-metal mechanism of RNA synthesis and degradation by RNA polymerase.
Sosunov V, Sosunova E, Mustaev A, Bass I, Nikiforov V, Goldfarb A. Sosunov V, et al. Among authors: mustaev a. EMBO J. 2003 May 1;22(9):2234-44. doi: 10.1093/emboj/cdg193. EMBO J. 2003. PMID: 12727889 Free PMC article.
Donation of catalytic residues to RNA polymerase active center by transcription factor Gre.
Sosunova E, Sosunov V, Kozlov M, Nikiforov V, Goldfarb A, Mustaev A. Sosunova E, et al. Among authors: mustaev a. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15469-74. doi: 10.1073/pnas.2536698100. Epub 2003 Dec 10. Proc Natl Acad Sci U S A. 2003. PMID: 14668436 Free PMC article.
The sigma 70 subunit of RNA polymerase induces lacUV5 promoter-proximal pausing of transcription.
Brodolin K, Zenkin N, Mustaev A, Mamaeva D, Heumann H. Brodolin K, et al. Among authors: mustaev a. Nat Struct Mol Biol. 2004 Jun;11(6):551-7. doi: 10.1038/nsmb768. Epub 2004 May 2. Nat Struct Mol Biol. 2004. PMID: 15122346
Homogeneous fluorescent assay for RNA polymerase.
Kozlov M, Bergendahl V, Burgess R, Goldfarb A, Mustaev A. Kozlov M, et al. Among authors: mustaev a. Anal Biochem. 2005 Jul 15;342(2):206-13. doi: 10.1016/j.ab.2005.04.022. Anal Biochem. 2005. PMID: 15950166
The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase.
Sosunov V, Zorov S, Sosunova E, Nikolaev A, Zakeyeva I, Bass I, Goldfarb A, Nikiforov V, Severinov K, Mustaev A. Sosunov V, et al. Among authors: mustaev a. Nucleic Acids Res. 2005 Jul 26;33(13):4202-11. doi: 10.1093/nar/gki688. Print 2005. Nucleic Acids Res. 2005. PMID: 16049026 Free PMC article.
Region 3.2 of the sigma subunit contributes to the binding of the 3'-initiating nucleotide in the RNA polymerase active center and facilitates promoter clearance during initiation.
Kulbachinskiy A, Mustaev A. Kulbachinskiy A, et al. Among authors: mustaev a. J Biol Chem. 2006 Jul 7;281(27):18273-6. doi: 10.1074/jbc.C600060200. Epub 2006 May 10. J Biol Chem. 2006. PMID: 16690607
Quinolones: action and resistance updated.
Drlica K, Hiasa H, Kerns R, Malik M, Mustaev A, Zhao X. Drlica K, et al. Among authors: mustaev a. Curr Top Med Chem. 2009;9(11):981-98. doi: 10.2174/156802609789630947. Curr Top Med Chem. 2009. PMID: 19747119 Free PMC article. Review.
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