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Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.
Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: mutsaers aj. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.
Genetically engineered mouse models and human osteosarcoma.
Ng AJ, Mutsaers AJ, Baker EK, Walkley CR. Ng AJ, et al. Among authors: mutsaers aj. Clin Sarcoma Res. 2012 Oct 4;2(1):19. doi: 10.1186/2045-3329-2-19. Clin Sarcoma Res. 2012. PMID: 23036272 Free PMC article.
Murine models of osteosarcoma: A piece of the translational puzzle.
Walia MK, Castillo-Tandazo W, Mutsaers AJ, Martin TJ, Walkley CR. Walia MK, et al. Among authors: mutsaers aj. J Cell Biochem. 2018 Jun;119(6):4241-4250. doi: 10.1002/jcb.26601. Epub 2018 Feb 27. J Cell Biochem. 2018. PMID: 29236321 Review.
Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs.
LeBlanc AK, Mazcko CN, Cherukuri A, Berger EP, Kisseberth WC, Brown ME, Lana SE, Weishaar K, Flesner BK, Bryan JN, Vail DM, Burton JH, Willcox JL, Mutsaers AJ, Woods JP, Northrup NC, Saba C, Curran KM, Leeper H, Wilson-Robles H, Wustefeld-Janssens BG, Lindley S, Smith AN, Dervisis N, Klahn S, Higginbotham ML, Wouda RM, Krick E, Mahoney JA, London CA, Barber LG, Balkman CE, McCleary-Wheeler AL, Suter SE, Martin O, Borgatti A, Burgess K, Childress MO, Fidel JL, Allstadt SD, Gustafson DL, Selmic LE, Khanna C, Fan TM. LeBlanc AK, et al. Among authors: mutsaers aj. Clin Cancer Res. 2021 Jun 1;27(11):3005-3016. doi: 10.1158/1078-0432.CCR-21-0315. Epub 2021 Mar 22. Clin Cancer Res. 2021. PMID: 33753454 Free PMC article.
60 results