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Interactions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 Mediate the cellular localization of nucleophosmin and its AML-associated mutants.
Mukherjee H, Chan KP, Andresen V, Hanley ML, Gjertsen BT, Myers AG. Mukherjee H, et al. Among authors: Myers AG. ACS Chem Biol. 2015 Mar 20;10(3):855-63. doi: 10.1021/cb500872g. Epub 2015 Jan 5. ACS Chem Biol. 2015. PMID: 25531824 Free PMC article.
A versatile synthesis of substituted isoquinolines.
Si C, Myers AG. Si C, et al. Among authors: Myers AG. Angew Chem Int Ed Engl. 2011 Oct 24;50(44):10409-13. doi: 10.1002/anie.201104769. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21910199 Free PMC article.
The natural product avrainvillamide binds to the oncoprotein nucleophosmin.
Wulff JE, Siegrist R, Myers AG. Wulff JE, et al. Among authors: Myers AG. J Am Chem Soc. 2007 Nov 21;129(46):14444-51. doi: 10.1021/ja075327f. Epub 2007 Oct 25. J Am Chem Soc. 2007. PMID: 17958425 Free PMC article.
A multiply convergent platform for the synthesis of trioxacarcins.
Švenda J, Hill N, Myers AG. Švenda J, et al. Among authors: Myers AG. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6709-14. doi: 10.1073/pnas.1015257108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245350 Free PMC article.
Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure.
Schaus SE, Cavalieri D, Myers AG. Schaus SE, et al. Among authors: Myers AG. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11075-80. doi: 10.1073/pnas.191340698. Epub 2001 Sep 18. Proc Natl Acad Sci U S A. 2001. PMID: 11562456 Free PMC article.
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