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DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP.
Deshpande RA, Myler LR, Soniat MM, Makharashvili N, Lee L, Lees-Miller SP, Finkelstein IJ, Paull TT. Deshpande RA, et al. Among authors: myler lr. Sci Adv. 2020 Jan 8;6(2):eaay0922. doi: 10.1126/sciadv.aay0922. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31934630 Free PMC article.
Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks.
Caron MC, Sharma AK, O'Sullivan J, Myler LR, Ferreira MT, Rodrigue A, Coulombe Y, Ethier C, Gagné JP, Langelier MF, Pascal JM, Finkelstein IJ, Hendzel MJ, Poirier GG, Masson JY. Caron MC, et al. Among authors: myler lr. Nat Commun. 2019 Jul 4;10(1):2954. doi: 10.1038/s41467-019-10741-9. Nat Commun. 2019. PMID: 31273204 Free PMC article.
RPA Phosphorylation Inhibits DNA Resection.
Soniat MM, Myler LR, Kuo HC, Paull TT, Finkelstein IJ. Soniat MM, et al. Among authors: myler lr. Mol Cell. 2019 Jul 11;75(1):145-153.e5. doi: 10.1016/j.molcel.2019.05.005. Epub 2019 May 29. Mol Cell. 2019. PMID: 31153714 Free PMC article.
Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex.
Myler LR, Soniat MM, Zhang X, Deshpande RA, Paull TT, Finkelstein IJ. Myler LR, et al. Methods Mol Biol. 2019;2004:269-287. doi: 10.1007/978-1-4939-9520-2_20. Methods Mol Biol. 2019. PMID: 31147924 Free PMC article.
Assembling the Human Resectosome on DNA Curtains.
Soniat MM, Myler LR, Finkelstein IJ. Soniat MM, et al. Among authors: myler lr. Methods Mol Biol. 2019;1999:225-244. doi: 10.1007/978-1-4939-9500-4_14. Methods Mol Biol. 2019. PMID: 31127580 Free PMC article.
Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex.
Dillard KE, Brown MW, Johnson NV, Xiao Y, Dolan A, Hernandez E, Dahlhauser SD, Kim Y, Myler LR, Anslyn EV, Ke A, Finkelstein IJ. Dillard KE, et al. Among authors: myler lr. Cell. 2018 Nov 1;175(4):934-946.e15. doi: 10.1016/j.cell.2018.09.039. Epub 2018 Oct 18. Cell. 2018. PMID: 30343903 Free PMC article.
Homeodomain Proteins Directly Regulate ATM Kinase Activity.
Johnson TE, Lee JH, Myler LR, Zhou Y, Mosley TJ, Yang SH; Bio-Bricks for Molecular Machines FRI Stream, Uprety N, Kim J, Paull TT. Johnson TE, et al. Among authors: myler lr. Cell Rep. 2018 Aug 7;24(6):1471-1483. doi: 10.1016/j.celrep.2018.06.089. Cell Rep. 2018. PMID: 30089259 Free PMC article.
Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.
Myler LR, Gallardo IF, Soniat MM, Deshpande RA, Gonzalez XB, Kim Y, Paull TT, Finkelstein IJ. Myler LR, et al. Mol Cell. 2017 Sep 7;67(5):891-898.e4. doi: 10.1016/j.molcel.2017.08.002. Epub 2017 Aug 31. Mol Cell. 2017. PMID: 28867292 Free PMC article.
Next-Generation DNA Curtains for Single-Molecule Studies of Homologous Recombination.
Soniat MM, Myler LR, Schaub JM, Kim Y, Gallardo IF, Finkelstein IJ. Soniat MM, et al. Among authors: myler lr. Methods Enzymol. 2017;592:259-281. doi: 10.1016/bs.mie.2017.03.011. Epub 2017 Apr 17. Methods Enzymol. 2017. PMID: 28668123 Free PMC article.
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