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Myostatin directly regulates skeletal muscle fibrosis.
Li ZB, Kollias HD, Wagner KR. Li ZB, et al. J Biol Chem. 2008 Jul 11;283(28):19371-8. doi: 10.1074/jbc.M802585200. Epub 2008 May 3. J Biol Chem. 2008. PMID: 18453534 Free PMC article.
Recent studies have shown that in the absence of the endogenous muscle growth regulator myostatin, regeneration of muscle is enhanced, and muscle fibrosis is correspondingly reduced. We now demonstrate that myostatin not only re
Recent studies have shown that in the absence of the endogenous muscle growth regulator myostatin, regeneration of m
Exogenous miR-26a suppresses muscle wasting and renal fibrosis in obstructive kidney disease.
Zhang A, Wang H, Wang B, Yuan Y, Klein JD, Wang XH. Zhang A, et al. FASEB J. 2019 Dec;33(12):13590-13601. doi: 10.1096/fj.201900884R. Epub 2019 Oct 8. FASEB J. 2019. PMID: 31593640 Free PMC article.
We hypothesized that exogenous miR-26 could suppresses renal fibrosis and muscle wasting in obstructive kidney disease. For this purpose, we generated exosomes that encapsulated miR-26, then injected these into skeletal muscle of UUO mice. ...Likewise, …
We hypothesized that exogenous miR-26 could suppresses renal fibrosis and muscle wasting in obstructive kidney disease. For th …
Myokines and Heart Failure: Challenging Role in Adverse Cardiac Remodeling, Myopathy, and Clinical Outcomes.
Berezin AE, Berezin AA, Lichtenauer M. Berezin AE, et al. Dis Markers. 2021 Jan 13;2021:6644631. doi: 10.1155/2021/6644631. eCollection 2021. Dis Markers. 2021. PMID: 33520013 Free PMC article. Review.
The pivotal role in the regulation of myocardial and skeletal muscle rejuvenation, attenuation of muscle metabolic homeostasis, and protection against ischemia injury and apoptosis belongs to myokines. Myokines are defined as a wide spectrum of active …
The pivotal role in the regulation of myocardial and skeletal muscle rejuvenation, attenuation of muscle metabol …