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Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.
Vrins CL, Out R, van Santbrink P, van der Zee A, Mahmoudi T, Groenendijk M, Havekes LM, van Berkel TJ, Willems van Dijk K, Biessen EA. Vrins CL, et al. PLoS One. 2013;8(2):e57492. doi: 10.1371/journal.pone.0057492. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23469003 Free PMC article.
Znf202 overexpression in mouse hepatoma cells mhAT3F2 resulted in downregulation of members of the Apoe/c1/c2 and Apoa1/c3/a4 gene cluster. The repressive activity of Znf202 was firmly confirmed in an apoE reporter assay and Znf202 responsive elements within the Apo …
Znf202 overexpression in mouse hepatoma cells mhAT3F2 resulted in downregulation of members of the Apoe/c1/c2 and Apoa1/c3/a4
Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster.
Hsu MC, Chang CS, Lee KT, Sun HY, Tsai YS, Kuo PH, Young KC, Wu CH. Hsu MC, et al. Nutr Diabetes. 2013 Mar 4;3(3):e61. doi: 10.1038/nutd.2013.2. Nutr Diabetes. 2013. PMID: 23459084 Free PMC article.
Furthermore, enhancement of ectopic fat deposition has been observed in both human studies and animal models of altered lipidemic control. Though APOA1/C3/A4/A5 genetic polymorphisms are associated with dyslipidemia, their effect on central obesity is less known. .. …
Furthermore, enhancement of ectopic fat deposition has been observed in both human studies and animal models of altered lipidemic control. T …