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Chemopreventive Potential of Myrtenal against Nitrosamine-Initiated, Radiation-Promoted Rat Bladder Carcinogenesis.
Farrag MA, Ezz MK, Ibrahim NK, Ahmed EK. Farrag MA, et al. Nutr Cancer. 2022;74(1):288-298. doi: 10.1080/01635581.2021.1879881. Epub 2021 Jan 29. Nutr Cancer. 2022. PMID: 33511885
In addition, myrtenal treatment caused a significant increase in caspase-3 activity and Bax/Bcl-2 ratio. Data obtained suggested that the anti-inflammatory effect and the induction of apoptosis contributed largely to the beneficial antitumor effects of myrtenal in r …
In addition, myrtenal treatment caused a significant increase in caspase-3 activity and Bax/Bcl-2 ratio. Data obtained suggested that …
Therapeutic Potential of Myrtenal and Its Derivatives-A Review.
Dragomanova S, Andonova V, Volcho K, Salakhutdinov N, Kalfin R, Tancheva L. Dragomanova S, et al. Life (Basel). 2023 Oct 20;13(10):2086. doi: 10.3390/life13102086. Life (Basel). 2023. PMID: 37895468 Free PMC article. Review.
Its chemical modifications often lead to new or more pronounced biological effects. As an example, the conjugation of myrtenal with the established pharmacophore adamantane enables the augmentation of several of its pivotal properties. Myrtenal-adamantane derivative …
Its chemical modifications often lead to new or more pronounced biological effects. As an example, the conjugation of myrtenal with t …
Anti-atherosclerotic Effects of Myrtenal in High-Fat Diet-Induced Atherosclerosis in Rats.
Yu L, Liu H, Ma X, Seshadri VD, Gao X. Yu L, et al. Appl Biochem Biotechnol. 2022 Dec;194(12):5717-5733. doi: 10.1007/s12010-022-04044-x. Epub 2022 Jul 9. Appl Biochem Biotechnol. 2022. PMID: 35804285
Furthermore, Myrtenal decreased ET, TXB2, and 6-keto-PGF1alpha levels indicating its anti-atherosclerotic activity. The study results thus indicate that Myrtenal modulates the lipid metabolic pathway to exert its anti-atherosclerotic activity....
Furthermore, Myrtenal decreased ET, TXB2, and 6-keto-PGF1alpha levels indicating its anti-atherosclerotic activity. The study results …
Syntheses of Complex Terpenes from Simple Polyprenyl Precursors.
Harmange Magnani CS, Thach DQ, Haelsig KT, Maimone TJ. Harmange Magnani CS, et al. Acc Chem Res. 2020 Apr 21;53(4):949-961. doi: 10.1021/acs.accounts.0c00055. Epub 2020 Mar 23. Acc Chem Res. 2020. PMID: 32202757 Free PMC article. Review.
Next, we describe the assembly of the antimalarial cardamom peroxide using a polyoxygenation cascade to fuse multiple units of molecular oxygen onto a dimeric skeleton. This three-to-four-step synthesis arises from (-)-myrtenal, an inexpensive pinene oxidation product. We …
Next, we describe the assembly of the antimalarial cardamom peroxide using a polyoxygenation cascade to fuse multiple units of molecular oxy …
Myrtenal attenuates oxidative stress and inflammation in a rat model of streptozotocin-induced diabetes.
Rathinam A, Pari L, Venkatesan M, Munusamy S. Rathinam A, et al. Arch Physiol Biochem. 2022 Feb;128(1):175-183. doi: 10.1080/13813455.2019.1670212. Epub 2019 Sep 28. Arch Physiol Biochem. 2022. PMID: 31564173
The present study was aimed to investigate the effect of myrtenal on diabetes-associated oxidative stress, lipid peroxidation (LPO), and inflammation using a rat model of streptozotocin (STZ)-induced diabetes. ...Our findings suggest that myrtenal may serve as an an …
The present study was aimed to investigate the effect of myrtenal on diabetes-associated oxidative stress, lipid peroxidation (LPO), …
Neuroprotective Effects of Myrtenal in an Experimental Model of Dementia Induced in Rats.
Dragomanova S, Pavlov S, Marinova D, Hodzev Y, Petralia MC, Fagone P, Nicoletti F, Lazarova M, Tzvetanova E, Alexandrova A, Kalfin R, Tancheva L. Dragomanova S, et al. Antioxidants (Basel). 2022 Feb 12;11(2):374. doi: 10.3390/antiox11020374. Antioxidants (Basel). 2022. PMID: 35204256 Free PMC article.
The animals were divided into 5 groups (1) Controls; (2) Sc; (3) Sc + Myrtenal (40 mg/kg), (4) Sc + Galantamine (1 mg/kg); (5) Sc + Lipoic acid (30 mg/kg). ...Histologically, the neuroprotective capacity of myrtenal was also confirmed. For the first time, we have de …
The animals were divided into 5 groups (1) Controls; (2) Sc; (3) Sc + Myrtenal (40 mg/kg), (4) Sc + Galantamine (1 mg/kg); (5) Sc + L …
Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice.
Akefe IO, Adegoke VA, Lamidi IY, Ameh MP, Idoga ES, Ubah SA, Ajayi IE. Akefe IO, et al. Curr Res Pharmacol Drug Discov. 2022 May 4;3:100106. doi: 10.1016/j.crphar.2022.100106. eCollection 2022. Curr Res Pharmacol Drug Discov. 2022. PMID: 35570857 Free PMC article.
Mice (n = 35) were randomly allocated into five cohorts consisting of 7 mice each; Group I: Control mice received vehicle alone; Group II: streptozotocin; Group III: streptozotocin + 100 mg/kg myrtenal; Group IV: streptozotocin +200 mg/kg myrtenal; and Group V: stre …
Mice (n = 35) were randomly allocated into five cohorts consisting of 7 mice each; Group I: Control mice received vehicle alone; Group II: s …
Potential molecular mechanisms of myrtenal against colon cancer: A systematic review.
Boopathy LK, Roy A, Gopal T, Kandy RRK, Arumugam MK. Boopathy LK, et al. J Biochem Mol Toxicol. 2024 Jan;38(1):e23525. doi: 10.1002/jbt.23525. Epub 2023 Sep 4. J Biochem Mol Toxicol. 2024. PMID: 37665681 Review.
Based on the research data's, the reviews focus on the anticancer property of myrtenal by emphasizing its therapeutic properties which downregulate the inflammasome pathways and other signalling pathways. ...This review highlights myrtenal and its biological potency …
Based on the research data's, the reviews focus on the anticancer property of myrtenal by emphasizing its therapeutic properties whic …
Monoterpenes and Their Derivatives-Recent Development in Biological and Medical Applications.
Zielińska-Błajet M, Feder-Kubis J. Zielińska-Błajet M, et al. Int J Mol Sci. 2020 Sep 25;21(19):7078. doi: 10.3390/ijms21197078. Int J Mol Sci. 2020. PMID: 32992914 Free PMC article. Review.
This review focuses on selected aliphatic, monocyclic, and bicyclic monoterpenes like geraniol, thymol, myrtenal, pinene, camphor, borneol, and their modified structures. ...
This review focuses on selected aliphatic, monocyclic, and bicyclic monoterpenes like geraniol, thymol, myrtenal, pinene, camphor, bo …
Myrtenal exhibits cardioprotective effects by attenuating the pathological progression associated with myocardial infarction.
Abhirami N, Chandran M, Ramadasan A, Bhasura D, Plakkal Ayyappan J. Abhirami N, et al. Fundam Clin Pharmacol. 2024 Apr;38(2):276-289. doi: 10.1111/fcp.12965. Epub 2023 Nov 21. Fundam Clin Pharmacol. 2024. PMID: 37990640
Antibacterial effect and biofilm formation were also done. RESULT: The findings revealed that Myrtenal alone had negligible cytotoxic effects and that Myrtenal protects H9c2 against H(2) O(2) -induced cell death at micromolar concentrations. ...Myrtenal also …
Antibacterial effect and biofilm formation were also done. RESULT: The findings revealed that Myrtenal alone had negligible cytotoxic …
123 results