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Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.
Näthke I. Näthke I. Nat Rev Cancer. 2006 Dec;6(12):967-74. doi: 10.1038/nrc2010. Epub 2006 Nov 9. Nat Rev Cancer. 2006. PMID: 17093505 Review.
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.
Barth AI, Näthke IS, Nelson WJ. Barth AI, et al. Among authors: nathke is. Curr Opin Cell Biol. 1997 Oct;9(5):683-90. doi: 10.1016/s0955-0674(97)80122-6. Curr Opin Cell Biol. 1997. PMID: 9330872 Review.
The adenomatous polyposis coli protein.
Näthke IS. Näthke IS. Mol Pathol. 1999 Aug;52(4):169-73. doi: 10.1136/mp.52.4.169. Mol Pathol. 1999. PMID: 10694935 Free PMC article. Review.
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation.
Zumbrunn J, Kinoshita K, Hyman AA, Näthke IS. Zumbrunn J, et al. Among authors: nathke is. Curr Biol. 2001 Jan 9;11(1):44-9. doi: 10.1016/s0960-9822(01)00002-1. Curr Biol. 2001. PMID: 11166179
Developmental expression of catenins and associated proteins during submucosal gland morphogenesis in the airway.
Ritchie TC, Zhou W, McKinstry E, Hosch M, Zhang Y, Nathke I, Engelhardt JF. Ritchie TC, et al. Among authors: nathke i. Exp Lung Res. 2001 Mar;27(2):121-41. doi: 10.1080/019021401750069375. Exp Lung Res. 2001. PMID: 11258801
A role for the Adenomatous Polyposis Coli protein in chromosome segregation.
Kaplan KB, Burds AA, Swedlow JR, Bekir SS, Sorger PK, Näthke IS. Kaplan KB, et al. Among authors: nathke is. Nat Cell Biol. 2001 Apr;3(4):429-32. doi: 10.1038/35070123. Nat Cell Biol. 2001. PMID: 11283619
The adenomatous polyposis coli protein: in the limelight out at the edge.
Dikovskaya D, Zumbrunn J, Penman GA, Näthke IS. Dikovskaya D, et al. Among authors: nathke is. Trends Cell Biol. 2001 Sep;11(9):378-84. doi: 10.1016/s0962-8924(01)02069-4. Trends Cell Biol. 2001. PMID: 11514192 Review.
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells.
Mogensen MM, Tucker JB, Mackie JB, Prescott AR, Näthke IS. Mogensen MM, et al. J Cell Biol. 2002 Jun 10;157(6):1041-8. doi: 10.1083/jcb.200203001. Epub 2002 Jun 10. J Cell Biol. 2002. PMID: 12058019 Free PMC article.
APC stabilizes microtubules in vivo and in vitro, and this may play a role in cell migration (Nathke, I.S., C.L. Adams, P. Polakis, J.H. Sellin, and W.J. Nelson. 1996. ...Cell Biol. 148:505-517; Zumbrunn, J., K. Inoshita, A.A. Hyman, and I.S. Nathke. 2 …
APC stabilizes microtubules in vivo and in vitro, and this may play a role in cell migration (Nathke, I.S., C.L. Adams, P. Pol …
The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.
Dikovskaya D, Newton IP, Näthke IS. Dikovskaya D, et al. Mol Biol Cell. 2004 Jun;15(6):2978-91. doi: 10.1091/mbc.e03-08-0613. Epub 2004 Apr 9. Mol Biol Cell. 2004. PMID: 15075372 Free PMC article.
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.
Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, Batlle E, Simon-Assmann P, Clevers H, Nathke IS, Clarke AR, Winton DJ. Sansom OJ, et al. Genes Dev. 2004 Jun 15;18(12):1385-90. doi: 10.1101/gad.287404. Genes Dev. 2004. PMID: 15198980 Free PMC article.
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