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Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors.
Tunaru S, Althoff TF, Nüsing RM, Diener M, Offermanns S. Tunaru S, et al. Among authors: nusing rm. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9179-84. doi: 10.1073/pnas.1201627109. Epub 2012 May 21. Proc Natl Acad Sci U S A. 2012. PMID: 22615395 Free PMC article.
Platelet-activating factor-induced pulmonary edema is partly mediated by prostaglandin E(2), E-prostanoid 3-receptors, and potassium channels.
Göggel R, Hoffman S, Nüsing R, Narumiya S, Uhlig S. Göggel R, et al. Among authors: nusing r. Am J Respir Crit Care Med. 2002 Sep 1;166(5):657-62. doi: 10.1164/rccm.200111-071OC. Am J Respir Crit Care Med. 2002. PMID: 12204861
Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor.
Tunaru S, Chennupati R, Nüsing RM, Offermanns S. Tunaru S, et al. Among authors: nusing rm. PLoS One. 2016 Sep 23;11(9):e0163633. doi: 10.1371/journal.pone.0163633. eCollection 2016. PLoS One. 2016. PMID: 27662627 Free PMC article.
LPA1 receptor-mediated thromboxane A2 release is responsible for lysophosphatidic acid-induced vascular smooth muscle contraction.
Dancs PT, Ruisanchez É, Balogh A, Panta CR, Miklós Z, Nüsing RM, Aoki J, Chun J, Offermanns S, Tigyi G, Benyó Z. Dancs PT, et al. Among authors: nusing rm. FASEB J. 2017 Apr;31(4):1547-1555. doi: 10.1096/fj.201600735R. Epub 2017 Jan 9. FASEB J. 2017. PMID: 28069828 Free PMC article.
The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2-mediated neuropathic pain induced by mechanical nerve damage.
Treutlein EM, Kern K, Weigert A, Tarighi N, Schuh CD, Nüsing RM, Schreiber Y, Ferreirós N, Brüne B, Geisslinger G, Pierre S, Scholich K. Treutlein EM, et al. Among authors: nusing rm. J Biol Chem. 2018 Jun 22;293(25):9685-9695. doi: 10.1074/jbc.RA118.002492. Epub 2018 May 11. J Biol Chem. 2018. PMID: 29752406 Free PMC article.
GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.
Benyó Z, Gille A, Kero J, Csiky M, Suchánková MC, Nüsing RM, Moers A, Pfeffer K, Offermanns S. Benyó Z, et al. Among authors: nusing rm. J Clin Invest. 2005 Dec;115(12):3634-40. doi: 10.1172/JCI23626. J Clin Invest. 2005. PMID: 16322797 Free PMC article.
Prostaglandin E2 induces vascular relaxation by E-prostanoid 4 receptor-mediated activation of endothelial nitric oxide synthase.
Hristovska AM, Rasmussen LE, Hansen PB, Nielsen SS, Nüsing RM, Narumiya S, Vanhoutte P, Skøtt O, Jensen BL. Hristovska AM, et al. Among authors: nusing rm. Hypertension. 2007 Sep;50(3):525-30. doi: 10.1161/HYPERTENSIONAHA.107.088948. Epub 2007 Jul 16. Hypertension. 2007. PMID: 17635857
PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice.
Vennemann A, Gerstner A, Kern N, Ferreiros Bouzas N, Narumiya S, Maruyama T, Nüsing RM. Vennemann A, et al. Among authors: nusing rm. Diabetes. 2012 Jul;61(7):1879-87. doi: 10.2337/db11-1396. Epub 2012 Apr 20. Diabetes. 2012. PMID: 22522619 Free PMC article.
Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney.
Morath R, Klein T, Seyberth HW, Nüsing RM. Morath R, et al. Among authors: nusing rm. J Am Soc Nephrol. 1999 Sep;10(9):1851-60. J Am Soc Nephrol. 1999. PMID: 10477136
Characterization and chromosomal mapping of the human thromboxane A2 receptor gene.
Nüsing RM, Hirata M, Kakizuka A, Eki T, Ozawa K, Narumiya S. Nüsing RM, et al. J Biol Chem. 1993 Nov 25;268(33):25253-9. J Biol Chem. 1993. PMID: 8227091
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