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Page 1
5-methoxy-N,N-diisopropyltryptamine-induced flashbacks.
Ikeda A, Sekiguchi K, Fujita K, Yamadera H, Koga Y. Ikeda A, et al. Am J Psychiatry. 2005 Apr;162(4):815. doi: 10.1176/appi.ajp.162.4.815. Am J Psychiatry. 2005. PMID: 15800171 No abstract available.
Human Hepatocyte 4-Acetoxy-N,N-Diisopropyltryptamine Metabolite Profiling by Reversed-Phase Liquid Chromatography Coupled with High-Resolution Tandem Mass Spectrometry.
Malaca S, Huestis MA, Lattanzio L, Marsella LT, Tagliabracci A, Carlier J, Busardò FP. Malaca S, et al. Metabolites. 2022 Jul 29;12(8):705. doi: 10.3390/metabo12080705. Metabolites. 2022. PMID: 36005577 Free PMC article.
There are few data on the metabolic pathways and enzymes involved in tryptamine biotransformation. 4-acetoxy-N,N-diisopropyltryptamine (4-AcO-DiPT) is a synthetic tryptamine related to 4-hydroxy-N,N-diisopropyltryptamine (4-OH-DiPT), 4-ac …
There are few data on the metabolic pathways and enzymes involved in tryptamine biotransformation. 4-acetoxy-N,N-diisopropy
Discriminative stimulus effects of N,N-diisopropyltryptamine.
Carbonaro TM, Forster MJ, Gatch MB. Carbonaro TM, et al. Psychopharmacology (Berl). 2013 Mar;226(2):241-6. doi: 10.1007/s00213-012-2891-x. Epub 2012 Oct 16. Psychopharmacology (Berl). 2013. PMID: 23070023 Free PMC article.
RATIONALE: Serotonergic hallucinogens such as (+)-lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT) produce distinctive visual effects, whereas the synthetic hallucinogen N,N-diisopropyltryptamine (DiPT) is known for its production of auditory dis …
RATIONALE: Serotonergic hallucinogens such as (+)-lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT) produce distinctive visual e …
Toxicology and Analysis of Psychoactive Tryptamines.
Malaca S, Lo Faro AF, Tamborra A, Pichini S, Busardò FP, Huestis MA. Malaca S, et al. Int J Mol Sci. 2020 Dec 4;21(23):9279. doi: 10.3390/ijms21239279. Int J Mol Sci. 2020. PMID: 33291798 Free PMC article. Review.
Tryptamines are 5-HT(2A) receptor agonists that produce altered perceptions of reality. Currently, the most prevalent tryptamines are 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT), 5-methoxy-N,N- diallyltryptamine (5-MeO-DALT) and dimethyltryptamine (DMT). …
Tryptamines are 5-HT(2A) receptor agonists that produce altered perceptions of reality. Currently, the most prevalent tryptamines are 5-meth …
Discriminative Stimulus Effects of Substituted Tryptamines in Rats.
Gatch MB, Hoch A, Carbonaro TM. Gatch MB, et al. ACS Pharmacol Transl Sci. 2020 Dec 29;4(2):467-471. doi: 10.1021/acsptsci.0c00173. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2020. PMID: 33860176 Free PMC article.
., 30 min) from saline. 4-Acetoxy-N,N-diethyltryptamine (4-AcO-DET), 4-hydroxy-N-methyl-N-ethyltryptamine (4-OH-MET), 4-hydroxy-N,N-diethyltryptamine (4-OH-DET), 4-acetoxy-N-methyl-N-isopropyltryptamine (4-AcO-MiPT), 4-acetoxy-N,N-dimethyltryptamine (4-AcO-DMT), 4-hydroxy-N,N-dim …
., 30 min) from saline. 4-Acetoxy-N,N-diethyltryptamine (4-AcO-DET), 4-hydroxy-N-methyl-N-ethyltryptamine (4-OH-MET), 4-hydroxy-N,N-diethylt …
Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N. Narimatsu S, et al. Biochem Pharmacol. 2006 Apr 28;71(9):1377-85. doi: 10.1016/j.bcp.2006.01.015. Epub 2006 Feb 28. Biochem Pharmacol. 2006. PMID: 16510126
In vitro quantitative studies of the oxidative metabolism of (5-methoxy-N,N-diisopropyltryptamine, 5-MeO-DIPT, Foxy) were performed using human liver microsomal fractions and recombinant CYP enzymes and synthetic 5-MeO-DIPT metabolites. 5-MeO-DIPT was mainly …
In vitro quantitative studies of the oxidative metabolism of (5-methoxy-N,N-diisopropyltryptamine, 5-MeO-DIPT, Foxy) we …
Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats.
Fantegrossi WE, Harrington AW, Kiessel CL, Eckler JR, Rabin RA, Winter JC, Coop A, Rice KC, Woods JH. Fantegrossi WE, et al. Pharmacol Biochem Behav. 2006 Jan;83(1):122-9. doi: 10.1016/j.pbb.2005.12.015. Epub 2006 Feb 3. Pharmacol Biochem Behav. 2006. PMID: 16460788
Few studies have examined the effects of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) in vivo. In these studies, 5-MeO-DIPT was tested in a drug-elicited head twitch assay in mice where it was compared to the structurally similar hallucinogen N,N-dimethyl …
Few studies have examined the effects of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) in vivo. In these studies, 5- …
Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N,N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites.
Kamata T, Katagi M, Kamata HT, Miki A, Shima N, Zaitsu K, Nishikawa M, Tanaka E, Honda K, Tsuchihashi H. Kamata T, et al. Drug Metab Dispos. 2006 Feb;34(2):281-7. doi: 10.1124/dmd.105.005835. Epub 2005 Nov 9. Drug Metab Dispos. 2006. PMID: 16280455
The urinary metabolites of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) in humans have been investigated by analyzing urine specimens from its users. ...Three major metabolic pathways were revealed as follows: 1) side chain degradation by O-demethylation …
The urinary metabolites of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) in humans have been investigated by analyzi …
Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N. Narimatsu S, et al. Biochem Pharmacol. 2008 Feb 1;75(3):752-60. doi: 10.1016/j.bcp.2007.09.019. Epub 2007 Sep 29. Biochem Pharmacol. 2008. PMID: 17980859
The oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), a tryptamine-type designer drug, was studied using rat liver microsomal fractions and recombinant cytochrome P450 (CYP) enzymes. 5-MeO-DIPT was biotransformed mainly into a side-cha …
The oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), a tryptamine-type designer drug, was stud …
Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy).
Nakagawa T, Kaneko S. Nakagawa T, et al. J Pharmacol Sci. 2008 Jan;106(1):2-8. doi: 10.1254/jphs.fm0070141. Epub 2008 Jan 16. J Pharmacol Sci. 2008. PMID: 18198474 Free article. Review.
In this review, our recent in vitro studies on the molecular targets and neural adaptation of methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"), and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT, "foxy") using Xenopus oocytes, organotypic …
In this review, our recent in vitro studies on the molecular targets and neural adaptation of methamphetamine, 3,4-methylenedioxymethampheta …
65 results