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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 1
1983 2
1984 1
1986 1
1988 1
1990 2
1993 2
1994 2
1995 1
1996 1
1997 3
1998 2
1999 3
2000 2
2001 7
2002 8
2003 19
2004 27
2005 26
2006 25
2007 25
2008 26
2009 28
2010 23
2011 36
2012 32
2013 38
2014 33
2015 33
2016 32
2017 24
2018 43
2019 29
2020 33
2021 29
2022 26
2023 13
2024 16
2025 26
2026 17

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614 results

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Page 1
Efficacy of N-Acetylcysteine in Preventing Acute Kidney Injury After Cardiac Surgery: A Meta-Analysis Study.
Mei M, Zhao HW, Pan QG, Pu YM, Tang MZ, Shen BB. Mei M, et al. J Invest Surg. 2018 Feb;31(1):14-23. doi: 10.1080/08941939.2016.1269853. Epub 2017 Jan 6. J Invest Surg. 2018. PMID: 28060555 Free article.
PURPOSE: To evaluate whether perioperative N-acetylcysteine (NAC) administration reduces the risk of cardiac surgery associated acute kidney injury (CSA-AKI). ...
PURPOSE: To evaluate whether perioperative N-acetylcysteine (NAC) administration reduces the risk of cardiac surgery associate …
Acute kidney injury.
Kellum JA, Unruh ML, Murugan R. Kellum JA, et al. BMJ Clin Evid. 2011 Mar 28;2011:2001. BMJ Clin Evid. 2011. PMID: 21443811 Free PMC article.
The term acute kidney injury has been introduced to encompass a wide spectrum of acute alterations in kidney function from mild to severe. ...METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical quest …
The term acute kidney injury has been introduced to encompass a wide spectrum of acute alterations in kidney …
Efficacy and safety of N-acetylcysteine for preventing post-intravenous contrast acute kidney injury in patients with kidney impairment: a systematic review and meta-analysis.
Maestro C, Leache L, Gutiérrez-Valencia M, Saiz LC, Gómez H, Bacaicoa MC, Erviti J. Maestro C, et al. Eur Radiol. 2023 Sep;33(9):6569-6581. doi: 10.1007/s00330-023-09577-1. Epub 2023 Apr 18. Eur Radiol. 2023. PMID: 37071164
OBJECTIVES: N-Acetylcysteine (NAC) may confer protection against post-contrast acute kidney injury (PC-AKI), although evidence is sparse and conflicting. ...KEY POINTS: N-Acetylcysteine may not significantly reduce the risk of …
OBJECTIVES: N-Acetylcysteine (NAC) may confer protection against post-contrast acute kidney injury (PC-AK …
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis.
Fan H, Le JW, Sun M, Zhu JH. Fan H, et al. Iran J Basic Med Sci. 2024;27(7):850-856. doi: 10.22038/IJBMS.2024.72882.15853. Iran J Basic Med Sci. 2024. PMID: 38800015 Free PMC article.
OBJECTIVES: To investigate the protective effect of N-acetylcysteine (NAC) on septic acute kidney injury (SAKI) via regulating Sirtuin3 (SIRT3)-mediated mitochondrial dysfunction and apoptosis. MATERIALS AND METHODS: By constructing SIRT3 knocko …
OBJECTIVES: To investigate the protective effect of N-acetylcysteine (NAC) on septic acute kidney injury …
Meta-analytic Techniques to Assess the Association Between N-acetylcysteine and Acute Kidney Injury After Contrast Administration: A Systematic Review and Meta-analysis.
Magner K, Ilin JV, Clark EG, Kong JWY, Davis A, Hiremath S. Magner K, et al. JAMA Netw Open. 2022 Jul 1;5(7):e2220671. doi: 10.1001/jamanetworkopen.2022.20671. JAMA Netw Open. 2022. PMID: 35788669 Free PMC article.
IMPORTANCE: The most suitable analytic method to systematically analyze numerous trials with contradictory results is unclear. Multiple trials assessing the use of N-acetylcysteine (NAC) for prevention of contrast-induced acute kidney injury (CI …
IMPORTANCE: The most suitable analytic method to systematically analyze numerous trials with contradictory results is unclear. Multiple tria …
N-acetylcysteine protects against star fruit-induced acute kidney injury.
Shimizu MH, Gois PH, Volpini RA, Canale D, Luchi WM, Froeder L, Heilberg IP, Seguro AC. Shimizu MH, et al. Ren Fail. 2017 Nov;39(1):193-202. doi: 10.1080/0886022X.2016.1256315. Epub 2016 Nov 15. Ren Fail. 2017. PMID: 27845599 Free PMC article.
BACKGROUND: Star fruit (SF) is a popular fruit, commonly cultivated in many tropical countries, that contains large amount of oxalate. Acute oxalate nephropathy and direct renal tubular damage through release of free radicals are the main mechanisms involved in SF-induced …
BACKGROUND: Star fruit (SF) is a popular fruit, commonly cultivated in many tropical countries, that contains large amount of oxalate. Ac …
Effect of N-acetylcysteine on prevention of contrast-associated acute kidney injury in patients with STEMI undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomised controlled trials.
Guo Z, Liu J, Lei L, Xue Y, Liu L, Huang H, Chen S, Liu Y, Lin Y, Tao J, Xu Q, Wu K, Zhang L, Chen JY. Guo Z, et al. BMJ Open. 2020 Oct 16;10(10):e039009. doi: 10.1136/bmjopen-2020-039009. BMJ Open. 2020. PMID: 33067289 Free PMC article.
OBJECTIVE: Several studies evaluating the preventive effect of N-acetylcysteine (NAC) on contrast-associated acute kidney injury (CA-AKI) among patients with ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coro …
OBJECTIVE: Several studies evaluating the preventive effect of N-acetylcysteine (NAC) on contrast-associated acute k …
Protective Effect of N-Acetylcysteine Pretreatment on Acute Kidney Injury in Septic Rats.
Fan H, Le JW, Zhu JH. Fan H, et al. J Surg Res. 2020 Oct;254:125-134. doi: 10.1016/j.jss.2020.04.017. Epub 2020 May 18. J Surg Res. 2020. PMID: 32438104
BACKGROUND: The aim of this study is to investigate the protective effect of N-acetylcysteine (NAC) pretreatment on acute kidney injury in septic rats. METHODS: We constructed a septic rat model by cecal ligation and perforation (CLP) and assess …
BACKGROUND: The aim of this study is to investigate the protective effect of N-acetylcysteine (NAC) pretreatment on acute …
Tannic acid-cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y. Fu H, et al. J Control Release. 2025 Apr 10;380:892-909. doi: 10.1016/j.jconrel.2025.02.038. Epub 2025 Feb 20. J Control Release. 2025. PMID: 39971251
Acute kidney injury (AKI) is a critical condition marked by a rapid decline in renal function, primarily driven by oxidative stress, mitochondrial dysfunction, and inflammation. ...Notably, TA-Ce outperformed the conventional anti-inflammatory drug N- …
Acute kidney injury (AKI) is a critical condition marked by a rapid decline in renal function, primarily driven by oxid …
614 results