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Year Number of Results
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338 results

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Page 1
N-acetylcysteine in Kidney Disease: Molecular Mechanisms, Pharmacokinetics, and Clinical Effectiveness.
Hernández-Cruz EY, Aparicio-Trejo OE, Hammami FA, Bar-Shalom D, Tepel M, Pedraza-Chaverri J, Scholze A. Hernández-Cruz EY, et al. Kidney Int Rep. 2024 Jul 20;9(10):2883-2903. doi: 10.1016/j.ekir.2024.07.020. eCollection 2024 Oct. Kidney Int Rep. 2024. PMID: 39430194 Free PMC article. Review.
N-acetylcysteine (NAC) has shown beneficial effects in both acute kidney disease and chronic kidney disease (CKD) in preclinical and clinical studies. ...In conclusion, studies on NAC treatment regimens need to account for both NAC
N-acetylcysteine (NAC) has shown beneficial effects in both acute kidney disease and chronic kidney
N-Acetylcysteine Alleviates the Progression of Chronic Kidney Disease: A Three-Year Cohort Study.
Chiu AH, Wang CJ, Lin YL, Wang CL, Chiang TI. Chiu AH, et al. Medicina (Kaunas). 2023 Nov 10;59(11):1983. doi: 10.3390/medicina59111983. Medicina (Kaunas). 2023. PMID: 38004033 Free PMC article.
Background and Objectives: The prevalence of chronic kidney disease (CKD) is approximately 10% of the population in many countries. CKD progresses to end-stage renal disease (ESRD), resulting in adverse outcomes, prolonged hospitalization, and i …
Background and Objectives: The prevalence of chronic kidney disease (CKD) is approximately 10% of the population in man …
N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis.
Ye M, Lin W, Zheng J, Lin S. Ye M, et al. Am J Transl Res. 2021 Apr 15;13(4):2472-2485. eCollection 2021. Am J Transl Res. 2021. PMID: 34017406 Free PMC article.
OBJECTIVE: The present study aimed to evaluate the safety and benefits of N-acetylcysteine (NAC) for chronic kidney disease (CKD) through a systematic review and meta-analysis. ...CONCLUSION: These results suggested that NAC appears to be safe w …
OBJECTIVE: The present study aimed to evaluate the safety and benefits of N-acetylcysteine (NAC) for chronic kidney
Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification.
Ye Y, Chen A, Li L, Liang Q, Wang S, Dong Q, Fu M, Lan Z, Li Y, Liu X, Ou JS, Lu L, Yan J. Ye Y, et al. Kidney Int. 2022 Dec;102(6):1259-1275. doi: 10.1016/j.kint.2022.07.034. Epub 2022 Sep 3. Kidney Int. 2022. PMID: 36063875
Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD). Cell death such as apoptosis plays a critical role in vascular calcification. ...Additionally, GSH depletion induced by erastin (a small molecule initiating …
Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD). Cell death such …
N-acetylcysteine delayed cadmium-induced chronic kidney injury by activating the sirtuin 1-P53 signaling pathway.
Dong W, Zhang K, Gong Z, Luo T, Li J, Wang X, Zou H, Song R, Zhu J, Ma Y, Liu G, Liu Z. Dong W, et al. Chem Biol Interact. 2023 Jan 5;369:110299. doi: 10.1016/j.cbi.2022.110299. Epub 2022 Dec 6. Chem Biol Interact. 2023. PMID: 36493885
With the development of modern industrial civilization, cadmium (Cd), a known nephrotoxic metal, has become a growing public safety issue due to its ability to induce various types of kidney disease. Maladaptive proximal tubule repair is a significant cause of Cd-in …
With the development of modern industrial civilization, cadmium (Cd), a known nephrotoxic metal, has become a growing public safety issue du …
Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials.
Alonso A, Lau J, Jaber BL, Weintraub A, Sarnak MJ. Alonso A, et al. Am J Kidney Dis. 2004 Jan;43(1):1-9. doi: 10.1053/j.ajkd.2003.09.009. Am J Kidney Dis. 2004. PMID: 14712421
BACKGROUND: Radiocontrast nephropathy (RCN) is a common cause of hospital-acquired acute renal failure. Results of several studies using N-acetylcysteine (NAC) for the prevention of RCN have yielded conflicting results. We performed a meta-analysis of group d …
BACKGROUND: Radiocontrast nephropathy (RCN) is a common cause of hospital-acquired acute renal failure. Results of several studies us …
Homocysteine-Lowering Interventions in Chronic Kidney Disease.
Badri S, Vahdat S, Seirafian S, Pourfarzam M, Gholipur-Shahraki T, Ataei S. Badri S, et al. J Res Pharm Pract. 2021 Dec 25;10(3):114-124. doi: 10.4103/jrpp.jrpp_75_21. eCollection 2021 Jul-Sep. J Res Pharm Pract. 2021. PMID: 35198504 Free PMC article. Review.
The incidence of cardiovascular events and mortality is higher in patients with chronic kidney disease (CKD) compared to the general population. Homocysteine (Hcy) appears to be an independent risk factor for cardiovascular diseases in general populations and …
The incidence of cardiovascular events and mortality is higher in patients with chronic kidney disease (CKD) compared t …
N-acetylcysteine treatment attenuates hemodialysis access-related limb pathophysiology in mice with chronic kidney disease.
Kim K, Cort TA, Kunz EM, Moerschel J, Palzkill VR, Dong G, Moparthy CN, Anderson EM, Fazzone B, O'Malley KA, Robinson ST, Berceli SA, Ryan TE, Scali ST. Kim K, et al. Am J Physiol Renal Physiol. 2023 Sep 1;325(3):F271-F282. doi: 10.1152/ajprenal.00083.2023. Epub 2023 Jul 13. Am J Physiol Renal Physiol. 2023. PMID: 37439200 Free PMC article.
The objective of the present study was to determine if treatment with N-acetylcysteine (NAC) could reduce access-related limb dysfunction in mice. Male and female C57BL6J mice were fed an adenine-supplemented diet to induce chronic kidney disease
The objective of the present study was to determine if treatment with N-acetylcysteine (NAC) could reduce access-related limb …
D-mannose for preventing and treating urinary tract infections.
Cooper TE, Teng C, Howell M, Teixeira-Pinto A, Jaure A, Wong G. Cooper TE, et al. Cochrane Database Syst Rev. 2022 Aug 30;8(8):CD013608. doi: 10.1002/14651858.CD013608.pub2. Cochrane Database Syst Rev. 2022. PMID: 36041061 Free PMC article.
Whilst many people may only experience a single episode in their lifetime and are generally responsive to standard antibiotics, a significant proportion of adults and children (approximately 15% to 25%) are chronic symptomatic UTI sufferers. Certain population groups are a …
Whilst many people may only experience a single episode in their lifetime and are generally responsive to standard antibiotics, a significan …
Antioxidants for chronic kidney disease.
Jun M, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, Webster AC, Perkovic V. Jun M, et al. Cochrane Database Syst Rev. 2012 Oct 17;10(10):CD008176. doi: 10.1002/14651858.CD008176.pub2. Cochrane Database Syst Rev. 2012. Update in: Cochrane Database Syst Rev. 2023 Nov 2;11:CD008176. doi: 10.1002/14651858.CD008176.pub3. PMID: 23076940 Free PMC article. Updated.
BACKGROUND: Chronic kidney disease (CKD) is a significant risk factor for premature cardiovascular disease and death. ...Two additional studies reported the effect of an oral antioxidant inflammation modulator in patients with CKD (estimated glomerular …
BACKGROUND: Chronic kidney disease (CKD) is a significant risk factor for premature cardiovascular disease and d …
338 results