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Efficacy of N-Acetylcysteine on Endometriosis-Related Pain, Size Reduction of Ovarian Endometriomas, and Fertility Outcomes.
Anastasi E, Scaramuzzino S, Viscardi MF, Viggiani V, Piccioni MG, Cacciamani L, Merlino L, Angeloni A, Muzii L, Porpora MG. Anastasi E, et al. Int J Environ Res Public Health. 2023 Mar 7;20(6):4686. doi: 10.3390/ijerph20064686. Int J Environ Res Public Health. 2023. PMID: 36981595 Free PMC article.
BACKGROUND: Endometriosis is a chronic, estrogen-dependent, inflammatory disease, whose pivotal symptoms are dysmenorrhea, dyspareunia, and chronic pelvic pain (CPP). Besides the usual medical treatments, recent evidence suggests there are potential benefits of oral N …
BACKGROUND: Endometriosis is a chronic, estrogen-dependent, inflammatory disease, whose pivotal symptoms are dysmenorrhea, dyspareuni …
N-acetylcysteine Clinical Applications.
Yahia Z, Yahia A, Abdelaziz T. Yahia Z, et al. Cureus. 2024 Oct 24;16(10):e72252. doi: 10.7759/cureus.72252. eCollection 2024 Oct. Cureus. 2024. PMID: 39450216 Free PMC article. Review.
This study aims to evaluate the therapeutic application of N-acetylcysteine (NAC) as a treatment or adjunct therapy for various medical conditions. ...It may be beneficial for polycystic ovary syndrome, endometriosis, male infertility, cataracts, glaucoma, dr …
This study aims to evaluate the therapeutic application of N-acetylcysteine (NAC) as a treatment or adjunct therapy for variou …
Dietary supplements for treatment of endometriosis: A review.
Yalçın Bahat P, Ayhan I, Üreyen Özdemir E, İnceboz Ü, Oral E. Yalçın Bahat P, et al. Acta Biomed. 2022 Mar 14;93(1):e2022159. doi: 10.23750/abm.v93i1.11237. Acta Biomed. 2022. PMID: 35315418 Free PMC article. Review.
We reviewed the literature, evaluated and synthesized effects of vitamin D, zinc, magnesium, omega 3, propolis, quercetin, curcumin, N-acetylcysteine, probiotics, resveratrol, alpha lipoic acid, vitamin C, vitamin E, selenium and epigallocatechin-3-gallate. Based on …
We reviewed the literature, evaluated and synthesized effects of vitamin D, zinc, magnesium, omega 3, propolis, quercetin, curcumin, N …
Targeting Oxidative Stress Involved in Endometriosis and Its Pain.
Clower L, Fleshman T, Geldenhuys WJ, Santanam N. Clower L, et al. Biomolecules. 2022 Jul 29;12(8):1055. doi: 10.3390/biom12081055. Biomolecules. 2022. PMID: 36008949 Free PMC article. Review.
Endometriosis is a common gynecological disorder seen in women and is characterized by chronic pelvic pain and infertility. ...N-acetylcysteine, curcumin, melatonin, and combined vitamin C and E supplementation displayed promising results for the treatment of …
Endometriosis is a common gynecological disorder seen in women and is characterized by chronic pelvic pain and infertility. ...N …
N-acetylcysteine stimulates organelle malfunction in endometriotic cells via IFN-gamma signaling.
Karakoç E, Halaçlı SO, Hanelçi RH, Ayhan S, Eylem CC, Nemutlu E, Atilla P. Karakoç E, et al. Sci Rep. 2025 Apr 29;15(1):15120. doi: 10.1038/s41598-025-00195-z. Sci Rep. 2025. PMID: 40301453 Free PMC article.
Endometriosis is a chronic inflammatory gynecologic disease characterized by the abnormal implantation of endometrial tissue outside the uterus. The inflammatory microenvironment of endometriosis is dominated by highly migratory endometriotic cells, inflammatory cel …
Endometriosis is a chronic inflammatory gynecologic disease characterized by the abnormal implantation of endometrial tissue outside …
Administration of N-acetylcysteine influence the expression of apoptotic genes in the granulosa cells of infertile women diagnosed with endometriosis.
Heshmati ZS, Amiri-Yekta A, Khosravifar M, Akbarian F, Moini A, Eftekhari-Yazdi P, Hafezi M, Afsharian P. Heshmati ZS, et al. Sci Rep. 2026 Feb 9;16(1):7961. doi: 10.1038/s41598-025-34202-0. Sci Rep. 2026. PMID: 41663453 Free PMC article. Clinical Trial.
N-acetylcysteine (NAC) is an antioxidant that reduces OS. This randomized controlled trial aimed to investigate the effects of NAC on serum levels of superoxide dismutase (SOD) and total antioxidant capacity (TAC), as well as the expression of apoptotic genes in gra …
N-acetylcysteine (NAC) is an antioxidant that reduces OS. This randomized controlled trial aimed to investigate the effects of …
Targeting inflammation in endometriosis: emerging therapeutic options.
Perrone U, Barra F, Anatrà M, Paudice M, Vellone VG, Gullo G, Ferrero S. Perrone U, et al. Expert Opin Investig Drugs. 2025 Dec;34(12):995-1009. doi: 10.1080/13543784.2025.2609734. Epub 2026 Jan 7. Expert Opin Investig Drugs. 2025. PMID: 41439725 Review.
Therapeutic approaches discussed comprise biologic agents (infliximab, etanercept, adalimumab, anakinra, tocilizumab), small-molecule JAK inhibitors (tofacitinib), and antioxidant compounds such as N-acetylcysteine, resveratrol, and vitamins C and E. EXPERT OPINION: …
Therapeutic approaches discussed comprise biologic agents (infliximab, etanercept, adalimumab, anakinra, tocilizumab), small-molecule JAK in …
The Role of Lifestyle and Diet in the Treatment of Endometriosis: A Review.
Boroncsok D, Filó A, Török M, Vágó H, Ács N, Sobel G. Boroncsok D, et al. Nutrients. 2026 Jan 1;18(1):142. doi: 10.3390/nu18010142. Nutrients. 2026. PMID: 41515258 Free PMC article. Review.
Endometriosis is a chronic, oestrogen-dependent inflammatory condition affecting approximately 10% of women of reproductive age, frequently associated with chronic pelvic pain, dysmenorrhoea and infertility, substantially impairing quality of life. ...Micronutrients and se …
Endometriosis is a chronic, oestrogen-dependent inflammatory condition affecting approximately 10% of women of reproductive age, freq …
Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.
Barrea L, Verde L, Annunziata G, Chedraui P, Petraglia F, Cucalón G, Camajani E, Caprio M, Gorini S, Iorio GG, Di Girolamo R, Carbone L, Chapela S, Frias-Toral E, Muscogiuri G. Barrea L, et al. Curr Obes Rep. 2025 Sep 8;14(1):68. doi: 10.1007/s13679-025-00662-8. Curr Obes Rep. 2025. PMID: 40920291 Free PMC article. Review.
This, therefore, implies the need to identify the different phenotypes of patients with endometriosis at which to target a precision MNT. Several dietary patterns and supplements have been investigated for their role in endometriosis management. ...Supplementation w …
This, therefore, implies the need to identify the different phenotypes of patients with endometriosis at which to target a precision …
Efficacy and Safety of N-Acetylcysteine for the Management of Chronic Pain in Adults: A Systematic Review and Meta-Analysis.
Mohiuddin M, Pivetta B, Gilron I, Khan JS. Mohiuddin M, et al. Pain Med. 2021 Dec 11;22(12):2896-2907. doi: 10.1093/pm/pnab042. Pain Med. 2021. PMID: 33560443
OBJECTIVE: To assess the efficacy and safety of N-acetylcysteine in the treatment of chronic pain. METHODS: A systematic search was carried out until April 2020 for clinical studies of N-acetylcysteine in the management of any persistent or recurrent c …
OBJECTIVE: To assess the efficacy and safety of N-acetylcysteine in the treatment of chronic pain. METHODS: A systematic searc …
31 results