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Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).
Fagerberg L, Oksvold P, Skogs M, Algenäs C, Lundberg E, Pontén F, Sivertsson A, Odeberg J, Klevebring D, Kampf C, Asplund A, Sjöstedt E, Al-Khalili Szigyarto C, Edqvist PH, Olsson I, Rydberg U, Hudson P, Ottosson Takanen J, Berling H, Björling L, Tegel H, Rockberg J, Nilsson P, Navani S, Jirström K, Mulder J, Schwenk JM, Zwahlen M, Hober S, Forsberg M, von Feilitzen K, Uhlén M. Fagerberg L, et al. Among authors: hudson p. J Proteome Res. 2013 Jun 7;12(6):2439-48. doi: 10.1021/pr300924j. Epub 2012 Dec 31. J Proteome Res. 2013. PMID: 23276153
We estimate that there is good evidence for protein existence for 69% (n = 13985) of the human protein-coding genes, while 23% have only evidence on the RNA level and 7% still lack experimental evidence. ...
We estimate that there is good evidence for protein existence for 69% (n = 13985) of the human protein-coding genes, while 23% have o …
Defining the role of a genetic counselor within pediatric hematology and oncology comprehensive care teams: Perspectives of the provider team and patients.
Hudson P, Zajo K, Gerhardt CA, Stanek J, Varga E. Hudson P, et al. J Genet Couns. 2019 Dec;28(6):1139-1147. doi: 10.1002/jgc4.1164. Epub 2019 Sep 3. J Genet Couns. 2019. PMID: 31478312
To assess perceptions of a GC's role in four pediatric hematology/oncology clinics, Accreditation Council for Genetic Counseling (ACGC) competencies were used to develop two separate surveys for providers and patients and their caregivers. Providers (n = 25) perceived role …
To assess perceptions of a GC's role in four pediatric hematology/oncology clinics, Accreditation Council for Genetic Counseling (ACGC) comp …
Poxvirus complement control proteins are expressed on the cell surface through an intermolecular disulfide bridge with the viral A56 protein.
DeHaven BC, Girgis NM, Xiao Y, Hudson PN, Olson VA, Damon IK, Isaacs SN. DeHaven BC, et al. Among authors: hudson pn. J Virol. 2010 Nov;84(21):11245-54. doi: 10.1128/JVI.00372-10. Epub 2010 Aug 18. J Virol. 2010. PMID: 20719953 Free PMC article.
Surface expression of VCP occurs though an interaction with the viral transmembrane protein A56 and is dependent on a free N-terminal cysteine of VCP. Although A56 and VCP have been shown to interact in infected cells, the mechanism remains unclear. ...
Surface expression of VCP occurs though an interaction with the viral transmembrane protein A56 and is dependent on a free N-terminal …
Combined ligand-observe (19)F and protein-observe (15)N,(1)H-HSQC NMR suggests phenylalanine as the key delta-somatostatin residue recognized by human protein disulfide isomerase.
Richards KL, Rowe ML, Hudson PB, Williamson RA, Howard MJ. Richards KL, et al. Among authors: hudson pb. Sci Rep. 2016 Jan 20;6:19518. doi: 10.1038/srep19518. Sci Rep. 2016. PMID: 26786784 Free PMC article.
We report a detailed study of specificity, interaction and dissociation constants (Kd) of the peptide-ligand delta-somatostatin (AGSKNFFWKTFTSS) binding to hPDI using (19)F ligand-observe and (15)N,(1)H-HSQC protein-observe NMR methods. Phe residues in delta-somatostatin a …
We report a detailed study of specificity, interaction and dissociation constants (Kd) of the peptide-ligand delta-somatostatin (AGSKNFFWKTF …