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Nanoparticle-Integrated Transdermal Patches: A Platform for Next-Generation Drug Delivery.
Mohan N, Nair RPAN, Narayanasamy D. Mohan N, et al. Drug Dev Res. 2025 Nov;86(7):e70164. doi: 10.1002/ddr.70164. Drug Dev Res. 2025. PMID: 40990940 Review.
This technology improves how much drug reaches the bloodstream and how long it acts, which can make drug delivery noninvasive and more comfortable for patients. ...This review rigorously analyzes various nanocarriers, including liposomes, niosomes, solid lipi …
This technology improves how much drug reaches the bloodstream and how long it acts, which can make drug delivery nonin …
Biodegradable beta-Cyclodextrin Conjugated Gelatin Methacryloyl Microneedle for Delivery of Water-Insoluble Drug.
Zhou X, Luo Z, Baidya A, Kim HJ, Wang C, Jiang X, Qu M, Zhu J, Ren L, Vajhadin F, Tebon P, Zhang N, Xue Y, Feng Y, Xue C, Chen Y, Lee K, Lee J, Zhang S, Xu C, Ashammakhi N, Ahadian S, Dokmeci MR, Gu Z, Sun W, Khademhosseini A. Zhou X, et al. Adv Healthc Mater. 2020 Jun;9(11):e2000527. doi: 10.1002/adhm.202000527. Epub 2020 May 4. Adv Healthc Mater. 2020. PMID: 32364331 Free PMC article.
However, direct loading of water-insoluble drug into hydrophilic matrices remains challenging. Here, a biodegradable MN array patch that is fabricated from naturally derived polymer conjugates of gelatin methacryloyl and beta-cyclodextrin (GelMA …
However, direct loading of water-insoluble drug into hydrophilic matrices remains challenging. Here, a biodegradable MN …
Beyond the skin barrier: from rational design to translational and market perspectives of hydrogel-forming microneedles.
Coelho de Carvalho Moreira LM, Oliveira do Amaral MK, Chaves LL, de La Rocca Soares MF, Soares-Sobrinho JL. Coelho de Carvalho Moreira LM, et al. Int J Pharm. 2026 May 20;697:126818. doi: 10.1016/j.ijpharm.2026.126818. Epub 2026 Mar 30. Int J Pharm. 2026. PMID: 41921704 Review.
The development of effective transdermal drug delivery systems remains a major challenge in modern pharmaceutics. Hydrogel-forming microneedles (HFMNs) have emerged as a promising platform, combining controlled drug release, biocompatibility, and minim …
The development of effective transdermal drug delivery systems remains a major challenge in modern pharmaceutics. Hydro …
Collagen- and Hyaluronic Acid-Based Microneedles With Thiolated Pectin for Redox-Responsive Drug Delivery.
Long W, George Joy J, Lee SJ, Kim JC. Long W, et al. J Biomed Mater Res A. 2025 Apr;113(4):e37903. doi: 10.1002/jbm.a.37903. J Biomed Mater Res A. 2025. PMID: 40156176
The objective of this study was to investigate the transdermal delivery efficacy of redox-responsive microneedle-containing thiolated pectin. ...In summary, the redox-responsive microneedle containing thiolated pectin may be a promising vehicle for transdermal …
The objective of this study was to investigate the transdermal delivery efficacy of redox-responsive microneedle-containing th …
An efficient approach to probe bioactive components of herbal patches by 2D-carbon microfiber fractionation and multi-chamber membrane separation electrophoresis: Spatholobus suberectus Dunn as a case.
Yang L, Cui H, Cui M, Qiu Y, Shao M, Zhu Y, Liu Y, Nardiello D, Quinto M, Shang HB, Liu H, Li D. Yang L, et al. J Pharm Biomed Anal. 2025 Aug 1;260:116791. doi: 10.1016/j.jpba.2025.116791. Epub 2025 Mar 5. J Pharm Biomed Anal. 2025. PMID: 40073537
However, due to the complexity of plant matrices and the extremely low content of transdermal components, the individuation of their effective bioactive compounds represents a challenge: there is then a great need for an efficient method to reveal the bioactive ingr …
However, due to the complexity of plant matrices and the extremely low content of transdermal components, the individuation of …