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Year Number of Results
2013 12
2014 16
2015 9
2016 16
2017 16
2018 5
2019 2
2020 1
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72 results
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Living systematic review: 1. Introduction-the why, what, when, and how.
Elliott JH, Synnot A, Turner T, Simmonds M, Akl EA, McDonald S, Salanti G, Meerpohl J, MacLehose H, Hilton J, Tovey D, Shemilt I, Thomas J; Living Systematic Review Network. Elliott JH, et al. J Clin Epidemiol. 2017 Nov;91:23-30. doi: 10.1016/j.jclinepi.2017.08.010. Epub 2017 Sep 11. J Clin Epidemiol. 2017. PMID: 28912002
D-galactose-induced brain ageing model: A systematic review and meta-analysis on cognitive outcomes and oxidative stress indices.
Sadigh-Eteghad S, Majdi A, McCann SK, Mahmoudi J, Vafaee MS, Macleod MR. Sadigh-Eteghad S, et al. PLoS One. 2017 Aug 30;12(8):e0184122. doi: 10.1371/journal.pone.0184122. eCollection 2017. PLoS One. 2017. PMID: 28854284 Free PMC article. Review.
Protocol for meta-analysis of temperature reduction in animal models of cardiac arrest.
Olai H, Thornéus G, Watson H, Macleod MR, Friberg H, Rhodes J, Nielsen N, Cronberg T, Deierborg T. Olai H, et al. Evid Based Preclin Med. 2016 Aug;3(1):e00014. doi: 10.1002/ebm2.14. Epub 2016 May 3. Evid Based Preclin Med. 2016. PMID: 27610239 Free PMC article.
The development of an online database for interventions tested in transgenic mouse models of Alzheimer's disease.
Egan KJ, Vesterinen HM, McCann SK, Sena ES, MacLeod MR. Egan KJ, et al. Evid Based Preclin Med. 2015 Aug;2(1):e00010. doi: 10.1002/ebm2.10. Epub 2015 Aug 11. Evid Based Preclin Med. 2015. PMID: 27570629 Free PMC article.
Despite many efforts by the research community, Alzheimer's disease (AD) is still an incurable neurodegenerative condition that affects an estimated 44 million individuals worldwide and this figure is expected to increase to 135 million by the year 2050. ...
Despite many efforts by the research community, Alzheimer's disease (AD) is still an incurable neurodegenerative condition that affec …
A systematic review and meta-analysis of topoisomerase inhibition in pre-clinical glioma models.
Jue TR, Sena ES, Macleod MR, McDonald KL, Hirst TC. Jue TR, et al. Oncotarget. 2018 Jan 29;9(13):11387-11401. doi: 10.18632/oncotarget.24334. eCollection 2018 Feb 16. Oncotarget. 2018. PMID: 29541421 Free PMC article.
The meta-analysis revealed that the overall effect of topoisomerase inhibition prolonged survival by a factor of 1.33 (95% CI: 1.23-1.43) and reduced tumor growth by a factor of 3.21 (95% CI: 1.99-5.88), with considerable between-study heterogeneity. . …
The meta-analysis revealed that the overall effect of topoisomerase inhibition prolonged survival by a factor of 1.33 (95% CI: 1
Machine learning algorithms for systematic review: reducing workload in a preclinical review of animal studies and reducing human screening error.
Bannach-Brown A, Przybyła P, Thomas J, Rice ASC, Ananiadou S, Liao J, Macleod MR. Bannach-Brown A, et al. Syst Rev. 2019 Jan 15;8(1):23. doi: 10.1186/s13643-019-0942-7. Syst Rev. 2019. PMID: 30646959 Free PMC article.
Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials.
Rewell SS, Churilov L, Sidon TK, Aleksoska E, Cox SF, Macleod MR, Howells DW. Rewell SS, et al. PLoS One. 2017 Feb 9;12(2):e0171688. doi: 10.1371/journal.pone.0171688. eCollection 2017. PLoS One. 2017. PMID: 28182727 Free PMC article.
Ischemic stroke was induced in 132 Spontaneously Hypertensive Rats which were assessed for behavioural and histological deficits at 1, 3, 7, 14, 21, 28 days, 12 and 24 weeks (n>11 per timepoint). ...
Ischemic stroke was induced in 132 Spontaneously Hypertensive Rats which were assessed for behavioural and histological deficits at 1
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement.
Macleod MR, Lawson McLean A, Kyriakopoulou A, Serghiou S, de Wilde A, Sherratt N, Hirst T, Hemblade R, Bahor Z, Nunes-Fonseca C, Potluru A, Thomson A, Baginskaite J, Egan K, Vesterinen H, Currie GL, Churilov L, Howells DW, Sena ES. Macleod MR, et al. PLoS Biol. 2015 Oct 13;13(10):e1002273. doi: 10.1371/journal.pbio.1002273. eCollection 2015 Oct. PLoS Biol. 2015. PMID: 26460723 Free PMC article.
The Experimental Design Assistant.
Percie du Sert N, Bamsey I, Bate ST, Berdoy M, Clark RA, Cuthill I, Fry D, Karp NA, Macleod M, Moon L, Stanford SC, Lings B. Percie du Sert N, et al. PLoS Biol. 2017 Sep 28;15(9):e2003779. doi: 10.1371/journal.pbio.2003779. eCollection 2017 Sep. PLoS Biol. 2017. PMID: 28957312 Free PMC article.
Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.
Hooijmans CR, de Vries RBM, Ritskes-Hoitinga M, Rovers MM, Leeflang MM, IntHout J, Wever KE, Hooft L, de Beer H, Kuijpers T, Macleod MR, Sena ES, Ter Riet G, Morgan RL, Thayer KA, Rooney AA, Guyatt GH, Schünemann HJ, Langendam MW; GRADE Working Group. Hooijmans CR, et al. PLoS One. 2018 Jan 11;13(1):e0187271. doi: 10.1371/journal.pone.0187271. eCollection 2018. PLoS One. 2018. PMID: 29324741 Free PMC article. Review.
Evidence summaries and certainty in the evidence ratings could also be used (1) to support selection of interventions with best therapeutic potential to be tested in clinical trials, (2) to justify a regulatory decision limiting human exposure (to drug or toxin), or to (3) …
Evidence summaries and certainty in the evidence ratings could also be used (1) to support selection of interventions with best thera …
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