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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
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1949 5
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1951 25
1952 12
1953 9
1954 2
1955 2
1956 1
1958 1
1959 2
1960 1
1962 1
1963 3
1964 7
1965 4
1966 1
1967 2
1968 4
1969 2
1970 1
1971 3
1972 1
1973 3
1974 7
1975 5
1976 5
1977 7
1978 7
1979 7
1980 4
1981 14
1982 31
1983 20
1984 24
1985 21
1986 18
1987 29
1988 31
1989 31
1990 27
1991 25
1992 28
1993 18
1994 17
1995 14
1996 22
1997 26
1998 27
1999 39
2000 51
2001 42
2002 48
2003 62
2004 76
2005 65
2006 79
2007 100
2008 102
2009 109
2010 87
2011 87
2012 78
2013 78
2014 77
2015 71
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2,115 results

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Page 1
Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus.
Horvath K, Jeitler K, Berghold A, Ebrahim SH, Gratzer TW, Plank J, Kaiser T, Pieber TR, Siebenhofer A. Horvath K, et al. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD005613. doi: 10.1002/14651858.CD005613.pub3. Cochrane Database Syst Rev. 2007. Update in: Cochrane Database Syst Rev. 2020 Nov 9;11:CD005613. doi: 10.1002/14651858.CD005613.pub4. PMID: 17443605 Free article. Updated.
Two large studies, the United Kingdom Prospective Diabetes Study (UKPDS) and the University Group Diabetes Program (UGDP), did not find a reduction of cardiovascular endpoints through improvement of metabolic control. The theoretical benefits of newer insulin analogues mig …
Two large studies, the United Kingdom Prospective Diabetes Study (UKPDS) and the University Group Diabetes Program (UGDP), did not find a re …
Safety and efficacy of insulin detemir versus NPH in the treatment of diabetes during pregnancy: Systematic review and meta-analysis of randomized controlled trials.
Athanasiadou KI, Paschou SA, Stamatopoulos T, Papakonstantinou E, Haidich AB, Goulis DG. Athanasiadou KI, et al. Diabetes Res Clin Pract. 2022 Aug;190:110020. doi: 10.1016/j.diabres.2022.110020. Epub 2022 Jul 22. Diabetes Res Clin Pract. 2022. PMID: 35878788
AIMS: To compare the safety and efficacy of insulin detemir versus neutral protamine Hagedorn (NPH) in pregnant women with diabetes. ...CONCLUSIONS: Insulin detemir was associated with less maternal hypoglycemic events and decreased risk for prematurity compa …
AIMS: To compare the safety and efficacy of insulin detemir versus neutral protamine Hagedorn (NPH) in pregnant women with dia …
Long-acting insulin analogues vs. NPH human insulin in type 1 diabetes. A meta-analysis.
Monami M, Marchionni N, Mannucci E. Monami M, et al. Diabetes Obes Metab. 2009 Apr;11(4):372-8. doi: 10.1111/j.1463-1326.2008.00976.x. Diabetes Obes Metab. 2009. PMID: 19267715 Review.
AIM: Basal insulin in type 1 diabetes can be provided using either NPH (Neutral Protamine Hagedorn) human insulin or long-acting insulin analogues, which are supposed to warrant a better metabolic control with reduced hypoglycaemic risk. Aim of this me …
AIM: Basal insulin in type 1 diabetes can be provided using either NPH (Neutral Protamine Hagedorn) human insulin or lo …
Insulin glargine versus NPH insulin in patients with type 1 diabetes.
Ratner R. Ratner R. Drugs Today (Barc). 2003 Nov;39(11):867-76. doi: 10.1358/dot.2003.39.11.799464. Drugs Today (Barc). 2003. PMID: 14702132 Review.
The episodes of hypoglycemia are problematic for patients taking intermediate-acting insulin preparations (i.e., NPH insulin), which have traditionally formed the mainstay basal insulin treatment. ...A number of clinical trials comparing the safety and …
The episodes of hypoglycemia are problematic for patients taking intermediate-acting insulin preparations (i.e., NPH insuli …
NPH insulin.
JAMIESON M, LACEY AH, FISHER AM. JAMIESON M, et al. Can Med Assoc J. 1951 Jul;65(1):20-3. Can Med Assoc J. 1951. PMID: 14848784 Free PMC article. No abstract available.
(Ultra-)long-acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus.
Semlitsch T, Engler J, Siebenhofer A, Jeitler K, Berghold A, Horvath K. Semlitsch T, et al. Cochrane Database Syst Rev. 2020 Nov 9;11(11):CD005613. doi: 10.1002/14651858.CD005613.pub4. Cochrane Database Syst Rev. 2020. PMID: 33166419 Free PMC article.
MAIN RESULTS: We identified 24 RCTs. Of these, 16 trials compared insulin glargine to NPH insulin and eight trials compared insulin detemir to NPH insulin. ...The incidence of adverse events was comparable for people treated with glargine …
MAIN RESULTS: We identified 24 RCTs. Of these, 16 trials compared insulin glargine to NPH insulin and eight trials comp …
Safety and efficacy of insulin detemir vs. insulin NPH in pregnant women with diabetes: a systematic review and meta-analysis.
Fatima K, Siddiqi AK, Shakil S, Akhtar SE, Quraishy MS, Siddiqui K, Rafique E, Maniya MT. Fatima K, et al. Minerva Obstet Gynecol. 2024 Dec;76(6):578-589. doi: 10.23736/S2724-606X.23.05318-6. Epub 2023 Oct 25. Minerva Obstet Gynecol. 2024. PMID: 37877940
Our pooled analysis demonstrates no statistically significant difference between the efficacy of insulin Detemir and insulin NPH as assessed by the HbA1c values from baseline. For safety outcomes, insulin detemir was significantly associated with a gre …
Our pooled analysis demonstrates no statistically significant difference between the efficacy of insulin Detemir and insulin …
NPH insulin.
CHEVALIER PR. CHEVALIER PR. J Maine Med Assoc. 1950 Nov;41(11):419-20. J Maine Med Assoc. 1950. PMID: 14784762 No abstract available.
Long-acting insulin analogues versus NPH human insulin in type 2 diabetes: a meta-analysis.
Monami M, Marchionni N, Mannucci E. Monami M, et al. Diabetes Res Clin Pract. 2008 Aug;81(2):184-9. doi: 10.1016/j.diabres.2008.04.007. Epub 2008 May 20. Diabetes Res Clin Pract. 2008. PMID: 18495286
BACKGROUND: Long-acting insulin analogues, in comparison with NPH insulin, should warrant a greater reproducibility of absorption after subcutaneous injection, providing better metabolic control with reduced hypoglycaemic risk. ...Detemir, but not glargine, c …
BACKGROUND: Long-acting insulin analogues, in comparison with NPH insulin, should warrant a greater reproducibility of …
Comparison of insulin glargine and NPH insulin in the treatment of type 2 diabetes: a review of clinical studies.
Duckworth W, Davis SN. Duckworth W, et al. J Diabetes Complications. 2007 May-Jun;21(3):196-204. doi: 10.1016/j.jdiacomp.2007.01.001. J Diabetes Complications. 2007. PMID: 17493554
A substantial amount of data exists comparing insulin glargine and neutral protamine Hagedorn (NPH) insulin for long-acting basal insulin coverage. ...Search terms included neutral protamine Hagedorn, NPH, insulin glargine, insulin …
A substantial amount of data exists comparing insulin glargine and neutral protamine Hagedorn (NPH) insulin for long-ac …
2,115 results