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Year Number of Results
1997 1
2001 1
2003 4
2004 4
2005 5
2006 4
2007 4
2008 1
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2010 2
2011 4
2012 3
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2015 6
2017 3
2018 3
2023 1

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46 results

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Page 1
Therapeutic potential of Liver Receptor Homolog-1 modulators.
Lazarus KA, Wijayakumara D, Chand AL, Simpson ER, Clyne CD. Lazarus KA, et al. J Steroid Biochem Mol Biol. 2012 Jul;130(3-5):138-46. doi: 10.1016/j.jsbmb.2011.12.017. Epub 2012 Jan 14. J Steroid Biochem Mol Biol. 2012. PMID: 22266285 Review.
Liver Receptor Homolog-1 (LRH-1; NR5A2) belongs to the orphan nuclear receptor superfamily, and plays vital roles in early development, cholesterol homeostasis, steroidogenesis and certain diseases, including cancer. It is expressed in embryonic stem cells, adult …
Liver Receptor Homolog-1 (LRH-1; NR5A2) belongs to the orphan nuclear receptor superfamily, and plays vital roles in early dev …
Molecular mechanisms of DAX1 action.
Iyer AK, McCabe ER. Iyer AK, et al. Mol Genet Metab. 2004 Sep-Oct;83(1-2):60-73. doi: 10.1016/j.ymgme.2004.07.018. Mol Genet Metab. 2004. PMID: 15464421 Review.
Recent evidence suggests a broader functional role for DAX1 as a negative coregulator of estrogen receptor (ER, NR3A1-2), liver receptor homologue-1 (LRH-1, NR5A2), androgen receptor (AR, NR3C4), and progesterone receptor (PR, NR3C3), each by distinct repression mec …
Recent evidence suggests a broader functional role for DAX1 as a negative coregulator of estrogen receptor (ER, NR3A1-2), liver recep …
Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer.
Nadolny C, Dong X. Nadolny C, et al. Cancer Biol Ther. 2015;16(7):997-1004. doi: 10.1080/15384047.2015.1045693. Epub 2015 May 7. Cancer Biol Ther. 2015. PMID: 25951367 Free PMC article. Review.
Liver receptor homolog-1 (LRH-1) is a nuclear receptor involved in various biological processes. This nuclear receptor has critical functions in embryonic development as well as in adult homeostasis. Although the physiological functions of LRH-1 in normal breast, pa …
Liver receptor homolog-1 (LRH-1) is a nuclear receptor involved in various biological processes. This nuclear receptor has critical f …
Expression of Liver Receptor Homolog-1 (LRH-1) in Villi and Decidua of Patients with Unexplained Recurrent Spontaneous Abortion.
Xu Z, Hou X, Lv H, Sun B, Cui Y, Liu L, Rong F. Xu Z, et al. Med Sci Monit. 2017 May 22;23:2445-2452. doi: 10.12659/msm.904645. Med Sci Monit. 2017. PMID: 28531169 Free PMC article.
BACKGROUND In view of the important function of nuclear receptor liver receptor homolog 1 (LRH 1) in various biological processes and the physiological changes accompanying unexplained recurrent spontaneous abortion (USRA), our study was carried out to investigate the pote …
BACKGROUND In view of the important function of nuclear receptor liver receptor homolog 1 (LRH 1) in various biological processes and …
Expression and functional analysis of liver receptor homologue 1 as a potential steroidogenic factor in rat ovary.
Liu DL, Liu WZ, Li QL, Wang HM, Qian D, Treuter E, Zhu C. Liu DL, et al. Biol Reprod. 2003 Aug;69(2):508-17. doi: 10.1095/biolreprod.102.011767. Epub 2003 Apr 2. Biol Reprod. 2003. PMID: 12672674
Liver receptor homologue 1 (LRH-1) is a member of the nuclear receptor superfamily originally found in liver cells. ...LRH-1 mRNA and protein were primarily localized to granulosa cells and luteinized follicles or newly formed corpora lutea (CLs) of immature and …
Liver receptor homologue 1 (LRH-1) is a member of the nuclear receptor superfamily originally found in liver cells. ...LRH-1 m …
Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis.
Labelle-Dumais C, Jacob-Wagner M, Paré JF, Bélanger L, Dufort D. Labelle-Dumais C, et al. Dev Dyn. 2006 Dec;235(12):3359-69. doi: 10.1002/dvdy.20996. Dev Dyn. 2006. PMID: 17075876 Free article.
NR5A2, also known as liver receptor homologue 1 (LRH-1) and fetoprotein transcription factor (FTF), is an orphan nuclear receptor involved in the regulation of cholesterol metabolism and steroidogenesis in the adult. NR5A2 was also shown to be expresse …
NR5A2, also known as liver receptor homologue 1 (LRH-1) and fetoprotein transcription factor (FTF), is an orphan nuclear recep …
Liver receptor homologue-1 and steroidogenic factor-1 expression in cultured granulosa cells from patients with endometriosis: A preliminary study.
Lu X, Wu ZM, Wang YW, Wang M, Cheng WW. Lu X, et al. J Obstet Gynaecol Res. 2015 Dec;41(12):1927-34. doi: 10.1111/jog.12832. Epub 2015 Nov 4. J Obstet Gynaecol Res. 2015. PMID: 26530052
AIM: The expression of aromatase (via CYP19 and the CYP19 PII promoter) and the orphan nuclear receptor family members, liver receptor homologue-1 (LRH-1) and steroidogenic factor-1 (SF-1) in cultured luteinized granulosa cells from women with endometriosis were investigat …
AIM: The expression of aromatase (via CYP19 and the CYP19 PII promoter) and the orphan nuclear receptor family members, liver recepto …
HBx induced AFP receptor expressed to activate PI3K/AKT signal to promote expression of Src in liver cells and hepatoma cells.
Zhu M, Guo J, Li W, Xia H, Lu Y, Dong X, Chen Y, Xie X, Fu S, Li M. Zhu M, et al. BMC Cancer. 2015 May 6;15:362. doi: 10.1186/s12885-015-1384-9. BMC Cancer. 2015. PMID: 25943101 Free PMC article.
But the role of AFP and AFPR in promoting occurrence of HBV-related HCC were still unclear. METHODS: A total of 71 clinical patients' liver specimens, normal human liver cells L-02 and HCC cell lines, PLC/PRF/5 were selected for analyzing the effects of HBx on expre …
But the role of AFP and AFPR in promoting occurrence of HBV-related HCC were still unclear. METHODS: A total of 71 clinical patients' liv …
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.
Wang W, Yang J, Liu H, Lu D, Chen X, Zenonos Z, Campos LS, Rad R, Guo G, Zhang S, Bradley A, Liu P. Wang W, et al. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18283-8. doi: 10.1073/pnas.1100893108. Epub 2011 Oct 11. Proc Natl Acad Sci U S A. 2011. PMID: 21990348 Free PMC article.
Here we report that enhancing RA signaling by expressing RA receptors (RARs) or by RA agonists profoundly promoted reprogramming, but inhibiting it using a RAR-alpha dominant-negative form completely blocked it. Coexpressing Rarg (RAR-gamma) and Lrh-1 (liver receptor homol …
Here we report that enhancing RA signaling by expressing RA receptors (RARs) or by RA agonists profoundly promoted reprogramming, but inhibi …
Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary.
Jiang Y, Zhao Y, Chen S, Chen L, Li C, Zhou X. Jiang Y, et al. Reprod Biol Endocrinol. 2018 Mar 20;16(1):25. doi: 10.1186/s12958-018-0348-8. Reprod Biol Endocrinol. 2018. PMID: 29558965 Free PMC article.
RESULTS: The present study demonstrated that the ovarian expression of Rbp4 remained constant before puberty and increased significantly in the peripubertal period. In adult female mice, the expression of Rbp4 increased at proestrus and peaked at estrus at both the mRNA an …
RESULTS: The present study demonstrated that the ovarian expression of Rbp4 remained constant before puberty and increased significantly in …
46 results