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Page 1
Use of non-steroidal anti-inflammatory drugs in pregnancy: impact on the fetus and newborn.
Antonucci R, Zaffanello M, Puxeddu E, Porcella A, Cuzzolin L, Pilloni MD, Fanos V. Antonucci R, et al. Curr Drug Metab. 2012 May 1;13(4):474-90. doi: 10.2174/138920012800166607. Curr Drug Metab. 2012. PMID: 22299823 Review.
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed in pregnancy to treat fever, pain and inflammation. ...Increased risks of miscarriage and malformations are associated with NSAID use in early pregnancy. …
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed in pregnancy to treat fever …
NSAIDs: maternal and fetal considerations.
Schoenfeld A, Bar Y, Merlob P, Ovadia Y. Schoenfeld A, et al. Am J Reprod Immunol. 1992 Oct-Dec;28(3-4):141-7. doi: 10.1111/j.1600-0897.1992.tb00777.x. Am J Reprod Immunol. 1992. PMID: 1285865 Review.
Nonsteroidal anti-inflammatory drugs (NSAIDs) gained popularity in the late 1970s. Inhibition of prostaglandin synthesis with indomethacin has been reported to be effective for prevention of labor and for treatment for symptomatic polyhydramnios. Concern abou …
Nonsteroidal anti-inflammatory drugs (NSAIDs) gained popularity in the late 1970s. Inhibition of prostaglandin synthesi …
Prostaglandin inhibitors in preterm labour.
Loudon JA, Groom KM, Bennett PR. Loudon JA, et al. Best Pract Res Clin Obstet Gynaecol. 2003 Oct;17(5):731-44. doi: 10.1016/s1521-6934(03)00047-6. Best Pract Res Clin Obstet Gynaecol. 2003. PMID: 12972011 Review.
Although indomethacin is currently the most common non-steroidal anti-inflammatory drug (NSAID) used in the treatment of preterm labour, it was hoped that COX-2-selective drugs, used as tocolytics, would target COX-2 activity and potentially spa …
Although indomethacin is currently the most common non-steroidal anti-inflammatory drug (NSAID) used in t …
Reversible oligohydramnios in the second trimester of pregnancy in two patients with long-term diclofenac exposure.
Scherneck S, Schöpa FL, Entezami M, Kayser A, Weber-Schoendorfer C, Schaefer C. Scherneck S, et al. Reprod Toxicol. 2015 Dec;58:61-4. doi: 10.1016/j.reprotox.2015.08.002. Epub 2015 Aug 28. Reprod Toxicol. 2015. PMID: 26318712
The use of non-steroidal anti-inflammatory drugs like diclofenac in the third trimester of pregnancy can cause severe side effects, in particular oligohydramnios, premature closure of ductus arteriosus, and fetal kidney damage. How …
The use of non-steroidal anti-inflammatory drugs like diclofenac in the third trimester of pregnancy can …
Fetal adverse effects following NSAID or metamizole exposure in the 2nd and 3rd trimester: an evaluation of the German Embryotox cohort.
Dathe K, Frank J, Padberg S, Hultzsch S, Beck E, Schaefer C. Dathe K, et al. BMC Pregnancy Childbirth. 2022 Aug 26;22(1):666. doi: 10.1186/s12884-022-04986-4. BMC Pregnancy Childbirth. 2022. PMID: 36028798 Free PMC article.
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used to treat pain, fever and inflammatory conditions. ...In one fetus, ductus arteriosus constriction and oligohydramnios occurred already in the late 2nd tr …
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used to treat pain, fever and in …
Nonsteroidal anti-inflammatory drugs during pregnancy and the initiation of lactation.
Bloor M, Paech M. Bloor M, et al. Anesth Analg. 2013 May;116(5):1063-1075. doi: 10.1213/ANE.0b013e31828a4b54. Epub 2013 Apr 4. Anesth Analg. 2013. PMID: 23558845 Review.
Nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin, which are available as "over-the counter" medications in most countries, are widely used by both pregnant and lactating women. ...NSAIDs and aspirin may affect fertility and increase the risk o …
Nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin, which are available as "over-the counter" medications in mos …
Risk estimation of fetal adverse effects after short-term second trimester exposure to non-steroidal anti-inflammatory drugs: a literature review.
Dathe K, Hultzsch S, Pritchard LW, Schaefer C. Dathe K, et al. Eur J Clin Pharmacol. 2019 Oct;75(10):1347-1353. doi: 10.1007/s00228-019-02712-2. Epub 2019 Jul 4. Eur J Clin Pharmacol. 2019. PMID: 31273431
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) are not recommended in the 3rd trimester of pregnancy due to known fetal adverse effects in an advanced gestational age. ...The search focused on case descriptions reporting defined …
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) are not recommended in the 3rd trimester of pr …
The promise of prostaglandins: have they fulfilled their potential as therapeutic targets for the delay of preterm birth?
Olson DM. Olson DM. J Soc Gynecol Investig. 2005 Oct;12(7):466-78. doi: 10.1016/j.jsgi.2005.06.004. J Soc Gynecol Investig. 2005. PMID: 16202923 Review.
METHODS AND RESULTS: Although early trials showed that nonsteroidal anti-inflammatory drugs (NSAIDs), which inhibit PG H synthase (PGHS), delayed preterm birth by 48 hours, other trials revealed an association between NSAIDs and adverse fetal effects, …
METHODS AND RESULTS: Although early trials showed that nonsteroidal anti-inflammatory drugs (NSAIDs), which inhibit PG …
Prolonged early antenatal indomethacin exposure is safe for fetus and neonate.
Turan OM, Driscoll C, Cetinkaya-Demir B, Gabbay-Benziv R, Turan S, Kopelman JN, Harman C. Turan OM, et al. J Matern Fetal Neonatal Med. 2021 Jan;34(2):167-176. doi: 10.1080/14767058.2019.1599351. Epub 2019 Apr 4. J Matern Fetal Neonatal Med. 2021. PMID: 30905227
They followed a standardized regiment of oral indomethacin: 100 mg loading, 50 mg qid for 48 h, 25 mg qid until delivery or at 32 weeks gestational age (GA), whichever comes first. Weekly monitoring for oligohydramnios and ductus arteriosus (DA) constriction include …
They followed a standardized regiment of oral indomethacin: 100 mg loading, 50 mg qid for 48 h, 25 mg qid until delivery or at 32 weeks gest …
30 results