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A tetrahydrophthalazine derivative 'sodium nucleinate" exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo.
Jukić T, Abidov M, Ihan A. Jukić T, et al. Coll Antropol. 2011 Dec;35(4):1219-23. Coll Antropol. 2011. PMID: 22397263
We described the use of a new chemical substance Sodium nucleinate (SN) as an immunomodulatory substance exhibiting antiinflammatory properties. Sodium nucleinate (SN) registrated in Russian Federation as Tamerit, is 2-amino-1,2,3,4-tetrahydrophthalazi …
We described the use of a new chemical substance Sodium nucleinate (SN) as an immunomodulatory substance exhibiting antiinflam …
[Effects and properties of sodium nucleinate used as a pyrogen working standard. 4. Acquired tolerance in rabbits following repeated intravenous injections of sodium nucleinate].
Dressel H. Dressel H. Pharmazie. 1987 Oct;42(10):671-4. Pharmazie. 1987. PMID: 3438320 German.
Evidently, this tolerance is without effect on the temperature increases due to subsequent sodium nucleinate injections, i. e. there is no cross tolerance between the bacterial lipopolysaccharide used for comparison and sodium nucleinate. A repeated …
Evidently, this tolerance is without effect on the temperature increases due to subsequent sodium nucleinate injections, i. e. …
Tetrahydrophthalazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes.
Jukić T, Ihan A, Jukić D. Jukić T, et al. Coll Antropol. 2012 Jun;36(2):409-12. Coll Antropol. 2012. PMID: 22856223
We described the use of a new chemical substance Sodium nucleinate (SN) as an immunomodulatory substance exhibiting antiinflammatory properties. Sodium nucleinate (SN) registrated in Russian Federation as Tamerit, is 2-amino-1,2,3,4-tetrahydrophthalazi …
We described the use of a new chemical substance Sodium nucleinate (SN) as an immunomodulatory substance exhibiting antiinflam …
Remarks on the investigation of sodium nucleinate by means of the limulus amebocyte lysate test.
Dressel H. Dressel H. Acta Biol Med Ger. 1976;35(7):1027-9. Acta Biol Med Ger. 1976. PMID: 1015160
Results of investigations of sodium nucleinate by means of the limulus amebocyte lysate (LAL) test are described. It was found that the sensitivity of this new pyrogen test to bacterial lipopolysaccharides is nearly the same as to sodium nucleinate, wh …
Results of investigations of sodium nucleinate by means of the limulus amebocyte lysate (LAL) test are described. It was found …
[Sodium nucleinate increase of nonspecific macroorganism resistance to conditionally pathogenic and pathogenic microorganisms].
Barsukov AA, Zemskov VM, Sobolev VR. Barsukov AA, et al. Antibiotiki. 1978 Jun;23(6):520-6. Antibiotiki. 1978. PMID: 677839 Russian.
It contains 1.5 per cent of protein and 2 per cent of DNA and does not contain any polysaccharides. Repeated purification of sodium nucleinate lowering the levels of the admixtures 5 times did not change its efficacy. ...On infection of the host stimulated with s …
It contains 1.5 per cent of protein and 2 per cent of DNA and does not contain any polysaccharides. Repeated purification of sodium …
The effect of sodium nucleinate on allergic and immunological reactions.
Zemskov AM, Sitnikova VP, Trutnev BD, Morozova VP, Kryukov VM, Nikitin AV, Yevstratova EF, Nastausheva TL. Zemskov AM, et al. J Hyg Epidemiol Microbiol Immunol. 1990;34(2):219-26. J Hyg Epidemiol Microbiol Immunol. 1990. PMID: 2212644
The findings on patients with the infectious form of bronchial asthma and chronic rheumatism showed that sodium nucleinate attenuated reactions to the subcutaneous administration of staphylococcal and streptococcal allergens. ...In children with acute glomerulonephr …
The findings on patients with the infectious form of bronchial asthma and chronic rheumatism showed that sodium nucleinate att …
[Use of sodium nucleinate and its combinations with bacterial polysaccharides for preventing the nephrotoxic action of aminoglycoside antibiotics].
Salakaia RG, Amirian NB. Salakaia RG, et al. Antibiotiki. 1984 Jul;29(7):507-9. Antibiotiki. 1984. PMID: 6486749 Russian.
Substances increasing the cell resistance (sodium nucleinate, prodigiosan and pyrogenal alone and sodium nucleinate combinations with the bacterial polysaccharides) were used. It was shown that sodium nucleinate prevented nephrotoxicity o …
Substances increasing the cell resistance (sodium nucleinate, prodigiosan and pyrogenal alone and sodium nucleinate …
183 results