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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1923 1
1931 1
1936 1
1947 3
1948 2
1951 2
1952 2
1954 3
1955 1
1957 1
1958 1
1959 2
1960 2
1962 2
1963 1
1964 6
1965 3
1966 11
1967 12
1968 11
1969 4
1970 9
1971 8
1972 11
1973 19
1974 21
1975 62
1976 118
1977 113
1978 134
1979 147
1980 163
1981 174
1982 217
1983 198
1984 213
1985 222
1986 246
1987 268
1988 271
1989 295
1990 390
1991 411
1992 446
1993 574
1994 641
1995 814
1996 982
1997 1109
1998 1358
1999 1503
2000 1851
2001 1991
2002 2077
2003 2426
2004 2646
2005 2849
2006 3082
2007 3307
2008 3246
2009 3413
2010 3494
2011 3620
2012 3703
2013 3726
2014 3765
2015 3757
2016 3554
2017 3392
2018 3540
2019 3358
2020 3021
2021 1
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69,890 results
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Page 1
Causal null hypotheses of sustained treatment strategies: What can be tested with an instrumental variable?
Swanson SA, Labrecque J, Hernán MA. Swanson SA, et al. Eur J Epidemiol. 2018 Aug;33(8):723-728. doi: 10.1007/s10654-018-0396-6. Epub 2018 May 2. Eur J Epidemiol. 2018. PMID: 29721747 Free PMC article. Review.
Sometimes instrumental variable methods are used to test whether a causal effect is null rather than to estimate the magnitude of a causal effect. ...Here, we consider different versions of causal null hypotheses for time-varying exposures, show that the instrumenta …
Sometimes instrumental variable methods are used to test whether a causal effect is null rather than to estimate the magnitude of a c …
CD28(null) pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of cardiovascular death.
Pera A, Caserta S, Albanese F, Blowers P, Morrow G, Terrazzini N, Smith HE, Rajkumar C, Reus B, Msonda JR, Verboom M, Hallensleben M, Blasczyk R, Davies KA, Kern F. Pera A, et al. Theranostics. 2018 Aug 7;8(16):4509-4519. doi: 10.7150/thno.27428. eCollection 2018. Theranostics. 2018. PMID: 30214635 Free PMC article.
Results: The median frequencies of CD28(null) CD4 T-cells and CD28(null) CD8 T-cells were >12-fold (p=0.000) but only approximately 2-fold higher (p=0.000), respectively, in CMV+ (n=136) compared with CMV- individuals (n=106). ...Over 75% of CMV-reactive CD4 T-ce …
Results: The median frequencies of CD28(null) CD4 T-cells and CD28(null) CD8 T-cells were >12-fold (p=0.000) but only appro …
CD28 (null) CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection.
Bano A, Pera A, Almoukayed A, Clarke THS, Kirmani S, Davies KA, Kern F. Bano A, et al. F1000Res. 2019 Mar 25;8:F1000 Faculty Rev-327. doi: 10.12688/f1000research.17119.1. eCollection 2019. F1000Res. 2019. PMID: 30984377 Free PMC article. Review.
Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28 (null)). ...In this review, we discuss how CMV might potentiate and exacerbate autoimmune disease through the expansion of CD28 (null) CD …
Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28 (null
Null Alleles and FIS × FST Correlations.
Waples RS. Waples RS. J Hered. 2018 May 11;109(4):457-461. doi: 10.1093/jhered/esy013. J Hered. 2018. PMID: 29554281
The result is an information gap regarding scenarios that include null alleles but have unbiased estimates of FST. Simulations were used to fill this information gap, with the following results: 1) converting ~10% of alleles to nulls substantially reduced apparent heterozy …
The result is an information gap regarding scenarios that include null alleles but have unbiased estimates of FST. Simulations were u …
Making 'null effects' informative: statistical techniques and inferential frameworks.
Harms C, Lakens D. Harms C, et al. J Clin Transl Res. 2018 Jul 30;3(Suppl 2):382-393. eCollection 2018 Jul 30. J Clin Transl Res. 2018. PMID: 30873486 Free PMC article.
Being able to interpret 'null effects?is important for cumulative knowledge generation in science. To draw informative conclusions from null-effects, researchers need to move beyond the incorrect interpretation of a non-significant result in a null-hypothesis …
Being able to interpret 'null effects?is important for cumulative knowledge generation in science. To draw informative conclusions fr …
Interpreting null findings from trials of alcohol brief interventions.
Heather N. Heather N. Front Psychiatry. 2014 Jul 16;5:85. doi: 10.3389/fpsyt.2014.00085. eCollection 2014. Front Psychiatry. 2014. PMID: 25076917 Free PMC article. Review.
This article first explains why null findings are likely to occur under null hypothesis significance testing (NHST) due to the phenomenon known as "the dance of the p-values." ...From the standpoint of scientific progress, the chief problem about null finding …
This article first explains why null findings are likely to occur under null hypothesis significance testing (NHST) due to the …
An omnibus test for the global null hypothesis.
Futschik A, Taus T, Zehetmayer S. Futschik A, et al. Stat Methods Med Res. 2019 Aug;28(8):2292-2304. doi: 10.1177/0962280218768326. Epub 2018 Apr 11. Stat Methods Med Res. 2019. PMID: 29635962 Free PMC article.
There are several possibilities how to test the global null hypothesis when the individual null hypotheses are independent. If it is assumed that many of the individual null hypotheses are false, combination tests have been recommended to maximize power. If, …
There are several possibilities how to test the global null hypothesis when the individual null hypotheses are independent. If …
The Null-Test for peptide identification algorithm in Shotgun proteomics.
Zhang SR, Shan YC, Jiang H, Liu JH, Zhou Y, Zhang LH, Zhang YK. Zhang SR, et al. J Proteomics. 2017 Jun 23;163:118-125. doi: 10.1016/j.jprot.2017.05.010. Epub 2017 May 12. J Proteomics. 2017. PMID: 28506863
The present research proposed general evaluation strategy named Null-Test for peptide identification algorithm in Shotgun proteomics. ...Unfortunately, none of the five famous identification software could pass the most stringent Null-Test. PatternLab had good perfo …
The present research proposed general evaluation strategy named Null-Test for peptide identification algorithm in Shotgun proteomics. …
The importance of proving the null.
Gallistel CR. Gallistel CR. Psychol Rev. 2009 Apr;116(2):439-53. doi: 10.1037/a0015251. Psychol Rev. 2009. PMID: 19348549 Free PMC article. Review.
Null hypotheses are simple, precise, and theoretically important. Conventional statistical analysis cannot support them; Bayesian analysis can. ...If the odds on the null approach 1 from above as the hypothesized maximum size of the possible effect approaches 0, the
Null hypotheses are simple, precise, and theoretically important. Conventional statistical analysis cannot support them; Bayesian ana
Null results in TMS: from absence of evidence to evidence of absence.
de Graaf TA, Sack AT. de Graaf TA, et al. Neurosci Biobehav Rev. 2011 Jan;35(3):871-7. doi: 10.1016/j.neubiorev.2010.10.006. Epub 2010 Oct 16. Neurosci Biobehav Rev. 2011. PMID: 20955732 Review.
Null results seem to inherently fulfill an important role in brain mapping. In fact, without null results, neuroimaging as an enterprise would not make sense. ...But how can null results inform us if they only constitute absence of evidence? We suggest that t
Null results seem to inherently fulfill an important role in brain mapping. In fact, without null results, neuroimaging as an
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