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14 results
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Total synthesis of hibispeptin A via Pd-catalyzed C(sp3)-H arylation with sterically hindered aryl iodides.
He G, Zhang SY, Nack WA, Pearson R, Rabb-Lynch J, Chen G. He G, et al. Among authors: nack wa. Org Lett. 2014 Dec 19;16(24):6488-91. doi: 10.1021/ol503347d. Epub 2014 Dec 9. Org Lett. 2014. PMID: 25487778
Efficient alkyl ether synthesis via palladium-catalyzed, picolinamide-directed alkoxylation of unactivated C(sp3)-H and C(sp2)-H bonds at remote positions.
Zhang SY, He G, Zhao Y, Wright K, Nack WA, Chen G. Zhang SY, et al. Among authors: nack wa. J Am Chem Soc. 2012 May 2;134(17):7313-6. doi: 10.1021/ja3023972. Epub 2012 Apr 19. J Am Chem Soc. 2012. PMID: 22486219
Palladium-catalyzed alkenylation and alkynylation of ortho-C(sp2)-H bonds of benzylamine picolinamides.
Zhao Y, He G, Nack WA, Chen G. Zhao Y, et al. Among authors: nack wa. Org Lett. 2012 Jun 15;14(12):2948-51. doi: 10.1021/ol301214u. Epub 2012 Jun 6. Org Lett. 2012. PMID: 22670792
Improved protocol for indoline synthesis via palladium-catalyzed intramolecular C(sp2)-H amination.
He G, Lu C, Zhao Y, Nack WA, Chen G. He G, et al. Among authors: nack wa. Org Lett. 2012 Jun 15;14(12):2944-7. doi: 10.1021/ol301352v. Epub 2012 Jun 6. Org Lett. 2012. PMID: 22670815
Palladium-catalyzed picolinamide-directed alkylation of unactivated C(sp3)-H bonds with alkyl iodides.
Zhang SY, He G, Nack WA, Zhao Y, Li Q, Chen G. Zhang SY, et al. Among authors: nack wa. J Am Chem Soc. 2013 Feb 13;135(6):2124-7. doi: 10.1021/ja312277g. Epub 2013 Jan 29. J Am Chem Soc. 2013. PMID: 23350845
Iodination of remote ortho-C-H bonds of arenes via directed S(E)Ar: a streamlined synthesis of tetrahydroquinolines.
Nack WA, He G, Zhang SY, Lu C, Chen G. Nack WA, et al. Org Lett. 2013 Jul 5;15(13):3440-3. doi: 10.1021/ol4015078. Epub 2013 Jun 20. Org Lett. 2013. PMID: 23786364
Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with primary alkyl halides.
Zhang SY, Li Q, He G, Nack WA, Chen G. Zhang SY, et al. Among authors: nack wa. J Am Chem Soc. 2013 Aug 14;135(32):12135-41. doi: 10.1021/ja406484v. Epub 2013 Aug 6. J Am Chem Soc. 2013. PMID: 23919290
Use of a readily removable auxiliary group for the synthesis of pyrrolidones by the palladium-catalyzed intramolecular amination of unactivated γ C(sp(3))-H bonds.
He G, Zhang SY, Nack WA, Li Q, Chen G. He G, et al. Among authors: nack wa. Angew Chem Int Ed Engl. 2013 Oct 11;52(42):11124-8. doi: 10.1002/anie.201305615. Epub 2013 Aug 27. Angew Chem Int Ed Engl. 2013. PMID: 24038874
Copper-catalyzed carboxamide-directed ortho amination of anilines with alkylamines at room temperature.
Li Q, Zhang SY, He G, Ai Z, Nack WA, Chen G. Li Q, et al. Among authors: nack wa. Org Lett. 2014 Mar 21;16(6):1764-7. doi: 10.1021/ol500464x. Epub 2014 Mar 4. Org Lett. 2014. PMID: 24588126
Palladium-catalyzed stereoretentive olefination of unactivated C(sp3)-H bonds with vinyl iodides at room temperature: synthesis of β-vinyl α-amino acids.
Wang B, Lu C, Zhang SY, He G, Nack WA, Chen G. Wang B, et al. Among authors: nack wa. Org Lett. 2014 Dec 5;16(23):6260-3. doi: 10.1021/ol503248f. Epub 2014 Nov 20. Org Lett. 2014. PMID: 25412205
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