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Year Number of Results
2014 2
2016 1
2017 3
2018 1
2019 1
2020 1
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8 results
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Page 1
The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.
Poulsen ET, Nielsen NS, Scavenius C, Mogensen EH, Risør MW, Runager K, Lukassen MV, Rasmussen CB, Christiansen G, Richner M, Vorum H, Enghild JJ. Poulsen ET, et al. Among authors: nielsen ns. J Biol Chem. 2019 Aug 2;294(31):11817-11828. doi: 10.1074/jbc.RA119.009050. Epub 2019 Jun 13. J Biol Chem. 2019. PMID: 31197037 Free PMC article.
Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies.
Nielsen NS, Poulsen ET, Lukassen MV, Chao Shern C, Mogensen EH, Weberskov CE, DeDionisio L, Schauser L, Moore TCB, Otzen DE, Hjortdal J, Enghild JJ. Nielsen NS, et al. Prog Retin Eye Res. 2020 Jul;77:100843. doi: 10.1016/j.preteyeres.2020.100843. Epub 2020 Jan 29. Prog Retin Eye Res. 2020. PMID: 32004730 Review.
Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein.
Nielsen NS, Juhl DW, Poulsen ET, Lukassen MV, Poulsen EC, Risør MW, Scavenius C, Enghild JJ. Nielsen NS, et al. Biochemistry. 2017 Dec 12;56(49):6470-6480. doi: 10.1021/acs.biochem.7b00668. Epub 2017 Nov 22. Biochemistry. 2017. PMID: 29140698
Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.
García-Castellanos R, Nielsen NS, Runager K, Thøgersen IB, Lukassen MV, Poulsen ET, Goulas T, Enghild JJ, Gomis-Rüth FX. García-Castellanos R, et al. Among authors: nielsen ns. Structure. 2017 Nov 7;25(11):1740-1750.e2. doi: 10.1016/j.str.2017.09.001. Epub 2017 Oct 5. Structure. 2017. PMID: 28988748 Free article.
Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies.
Poulsen ET, Runager K, Nielsen NS, Lukassen MV, Thomsen K, Snider P, Simmons O, Vorum H, Conway SJ, Enghild JJ. Poulsen ET, et al. Among authors: nielsen ns. FEBS J. 2018 Jan;285(1):101-114. doi: 10.1111/febs.14321. Epub 2017 Nov 23. FEBS J. 2018. PMID: 29117645 Free PMC article.
LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).
Poulsen ET, Nielsen NS, Jensen MM, Nielsen E, Hjortdal J, Kim EK, Enghild JJ. Poulsen ET, et al. Among authors: nielsen ns. Proteomics. 2016 Feb;16(3):539-43. doi: 10.1002/pmic.201500287. Epub 2016 Jan 3. Proteomics. 2016. PMID: 26864644
Proteomic investigation of cultivated fibroblasts from patients with mitochondrial short-chain acyl-CoA dehydrogenase deficiency.
Edhager AV, Stenbroen V, Nielsen NS, Bross P, Olsen RKJ, Gregersen N, Palmfeldt J. Edhager AV, et al. Among authors: nielsen ns. Mol Genet Metab. 2014 Mar;111(3):360-368. doi: 10.1016/j.ymgme.2014.01.007. Epub 2014 Jan 24. Mol Genet Metab. 2014. PMID: 24485985
Insight into the Protein Composition of Immunoglobulin Light Chain Deposits of Eyelid, Orbital and Conjunctival Amyloidosis.
Nielsen NS, Poulsen ET, Klintworth GK, Enghild JJ. Nielsen NS, et al. J Proteomics Bioinform. 2014;Suppl 8:002. doi: 10.4172/jpb.S8-002. Epub 2014 Apr 21. J Proteomics Bioinform. 2014. PMID: 26500418 Free PMC article.