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The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes.
Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. Vonderheide RH, et al. Among authors: nadler lm. Immunity. 1999 Jun;10(6):673-9. doi: 10.1016/s1074-7613(00)80066-7. Immunity. 1999. PMID: 10403642
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes.
Boussiotis VA, Freeman GJ, Taylor PA, Berezovskaya A, Grass I, Blazar BR, Nadler LM. Boussiotis VA, et al. Among authors: nadler lm. Nat Med. 2000 Mar;6(3):290-7. doi: 10.1038/73144. Nat Med. 2000. PMID: 10700231
Studies of in vitro activated CD5+ B cells.
Freedman AS, Freeman G, Whitman J, Segil J, Daley J, Nadler LM. Freedman AS, et al. Among authors: nadler lm. Blood. 1989 Jan;73(1):202-8. Blood. 1989. PMID: 2462935
B7, a B-cell-restricted antigen that identifies preactivated B cells.
Freedman AS, Freeman G, Horowitz JC, Daley J, Nadler LM. Freedman AS, et al. Among authors: nadler lm. J Immunol. 1987 Nov 15;139(10):3260-7. J Immunol. 1987. PMID: 3500211
Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.
Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA. Barata JT, et al. Among authors: nadler lm. Haematologica. 2004 Dec;89(12):1459-67. Haematologica. 2004. PMID: 15590396
Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia.
Maia S, Haining WN, Ansén S, Xia Z, Armstrong SA, Seth NP, Ghia P, den Boer ML, Pieters R, Sallan SE, Nadler LM, Cardoso AA. Maia S, et al. Among authors: nadler lm. Cancer Res. 2005 Nov 1;65(21):10050-8. doi: 10.1158/0008-5472.CAN-05-1574. Cancer Res. 2005. PMID: 16267031
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
Hirano N, Butler MO, Xia Z, Ansén S, von Bergwelt-Baildon MS, Neuberg D, Freeman GJ, Nadler LM. Hirano N, et al. Among authors: nadler lm. Blood. 2006 Feb 15;107(4):1528-36. doi: 10.1182/blood-2005-05-2073. Epub 2005 Oct 20. Blood. 2006. PMID: 16239433 Free PMC article.
Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia.
Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM. Haining WN, et al. Among authors: nadler lm. Blood. 2005 Sep 1;106(5):1749-54. doi: 10.1182/blood-2005-03-1082. Epub 2005 May 26. Blood. 2005. PMID: 15920008 Free PMC article. Clinical Trial.
The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells.
Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, Nadler LM, Schultze JL. Maecker B, et al. Among authors: nadler lm. Blood. 2003 Nov 1;102(9):3287-94. doi: 10.1182/blood-2003-05-1374. Epub 2003 Jul 17. Blood. 2003. PMID: 12869499
Autoantibodies frequently detected in patients with aplastic anemia.
Hirano N, Butler MO, Von Bergwelt-Baildon MS, Maecker B, Schultze JL, O'Connor KC, Schur PH, Kojima S, Guinan EC, Nadler LM. Hirano N, et al. Among authors: nadler lm. Blood. 2003 Dec 15;102(13):4567-75. doi: 10.1182/blood-2002-11-3409. Epub 2003 Aug 28. Blood. 2003. PMID: 12947009
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