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Successful treatment of an adolescent with Naegleria fowleri primary amebic meningoencephalitis.
Linam WM, Ahmed M, Cope JR, Chu C, Visvesvara GS, da Silva AJ, Qvarnstrom Y, Green J. Linam WM, et al. Pediatrics. 2015 Mar;135(3):e744-8. doi: 10.1542/peds.2014-2292. Epub 2015 Feb 9. Pediatrics. 2015. PMID: 25667249 Free PMC article.
Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely …
Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are near …
Naegleria fowleri: Diagnosis, Pathophysiology of Brain Inflammation, and Antimicrobial Treatments.
Pugh JJ, Levy RA. Pugh JJ, et al. ACS Chem Neurosci. 2016 Sep 21;7(9):1178-9. doi: 10.1021/acschemneuro.6b00232. Epub 2016 Aug 15. ACS Chem Neurosci. 2016. PMID: 27525348
In the past 50 years, there have been over 130 cases of Naegleria induced PAM in the United States with only three known survivors; one survivor was diagnosed and treated at Arkansas Children's Hospital. Successful treatment of PAM started with a rapid …
In the past 50 years, there have been over 130 cases of Naegleria induced PAM in the United States with only three known survivors …
Primary Amoebic Meningoencephalitis caused by Complement C2 Deficiency.
Cui J, Roark CM, Domínguez-Pinilla N, Nozal Aranda P, Losada B, Zamarrón P, Lorenzo-Morales J, Rubio Muñoz JM, Dobrose MM, Van den Rym A, Allende LM, Shelton C, Reyna DE, Markle JG, Rodríguez de Córdoba S, Lopez-Trascasa M, Pérez de Diego R, Serezani CH, Byndloss MX, de Fuentes Corripio I, González-Granado LI, Martinez-Barricarte R. Cui J, et al. medRxiv [Preprint]. 2026 Feb 2:2026.01.31.26345168. doi: 10.64898/2026.01.31.26345168. medRxiv. 2026. PMID: 41674601 Free PMC article. Preprint.
BACKGROUND: Primary amoebic meningoencephalitis (PAM) is a rapidly progressive and often fatal central nervous system infection caused by Naegleria fowleri. Despite widespread environmental exposure to this free-living amoeba, clinical disease is rare, suggesting th …
BACKGROUND: Primary amoebic meningoencephalitis (PAM) is a rapidly progressive and often fatal central nervous system infection caused by …
Primary Amebic Meningoencephalitis in Children: A Report of Two Fatal Cases and Review of the Literature.
Stowe RC, Pehlivan D, Friederich KE, Lopez MA, DiCarlo SM, Boerwinkle VL. Stowe RC, et al. Pediatr Neurol. 2017 May;70:75-79. doi: 10.1016/j.pediatrneurol.2017.02.004. Epub 2017 Feb 22. Pediatr Neurol. 2017. PMID: 28389055 Review.
BACKGROUND: Primary amebic meningoencephalitis is a rare, almost uniformly fatal disease of cerebral invasion by Naegleria fowleri, occurring most commonly after swimming in warm fresh water in summer months. Treatment using the experimental medication mil …
BACKGROUND: Primary amebic meningoencephalitis is a rare, almost uniformly fatal disease of cerebral invasion by Naegleria fowleri …