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CRISPR/Cas9-Mediated Knockout of Rb1 in Xenopus tropicalis.
Naert T, Vleminckx K. Naert T, et al. Methods Mol Biol. 2018;1726:177-193. doi: 10.1007/978-1-4939-7565-5_16. Methods Mol Biol. 2018. PMID: 29468553
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis.
Naert T, Colpaert R, Van Nieuwenhuysen T, Dimitrakopoulou D, Leoen J, Haustraete J, Boel A, Steyaert W, Lepez T, Deforce D, Willaert A, Creytens D, Vleminckx K. Naert T, et al. Sci Rep. 2016 Oct 14;6:35264. doi: 10.1038/srep35264. Sci Rep. 2016. PMID: 27739525 Free PMC article.
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B. Szenker-Ravi E, et al. Among authors: Naert T. Nature. 2018 May;557(7706):564-569. doi: 10.1038/s41586-018-0118-y. Epub 2018 May 16. Nature. 2018. PMID: 29769720
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis.
Naert T, Dimitrakopoulou D, Tulkens D, Demuynck S, Carron M, Noelanders R, Eeckhout L, Van Isterdael G, Deforce D, Vanhove C, Van Dorpe J, Creytens D, Vleminckx K. Naert T, et al. Oncogene. 2020 Mar;39(13):2692-2706. doi: 10.1038/s41388-020-1173-z. Epub 2020 Jan 30. Oncogene. 2020. PMID: 32001819
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