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alpha-Catenin as a tension transducer that induces adherens junction development.
Yonemura S, Wada Y, Watanabe T, Nagafuchi A, Shibata M. Yonemura S, et al. Among authors: nagafuchi a. Nat Cell Biol. 2010 Jun;12(6):533-42. doi: 10.1038/ncb2055. Epub 2010 May 9. Nat Cell Biol. 2010. PMID: 20453849
Functional analysis of ectodermal β-catenin during external genitalia formation.
Mazahery AR, Suzuki K, Nagafuchi A, Miyajima M, Nakagata N, Orvis GD, Behringer RR, Yamada G. Mazahery AR, et al. Among authors: nagafuchi a. Congenit Anom (Kyoto). 2013 Mar;53(1):34-41. doi: 10.1111/cga.12001. Congenit Anom (Kyoto). 2013. PMID: 23480356
Defining the roles of α-catenin in cell adhesion and cytoskeleton organization: isolation of F9 cells completely lacking cadherin-catenin complex.
Ozono K, Komiya S, Shimamura K, Ito T, Nagafuchi A. Ozono K, et al. Among authors: nagafuchi a. Cell Struct Funct. 2011;36(1):131-43. doi: 10.1247/csf.11009. Cell Struct Funct. 2011. PMID: 21685705 Free article.
Defining the roles of beta-catenin and plakoglobin in cell-cell adhesion: isolation of beta-catenin/plakoglobin-deficient F9 cells.
Fukunaga Y, Liu H, Shimizu M, Komiya S, Kawasuji M, Nagafuchi A. Fukunaga Y, et al. Among authors: nagafuchi a. Cell Struct Funct. 2005;30(2):25-34. doi: 10.1247/csf.30.25. Cell Struct Funct. 2005. PMID: 16357441
Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.
Oda T, Kanai Y, Shimoyama Y, Nagafuchi A, Tsukita S, Hirohashi S. Oda T, et al. Among authors: nagafuchi a. Biochem Biophys Res Commun. 1993 Jun 30;193(3):897-904. doi: 10.1006/bbrc.1993.1710. Biochem Biophys Res Commun. 1993. PMID: 8323564
., one of 957 bp deletion resulting in a 319-amino-acid deletion and another of 761 bp deletion resulting in a frameshift, were identified. ...
., one of 957 bp deletion resulting in a 319-amino-acid deletion and another of 761 bp deletion resulting in a frameshift, wer …
alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadin.
Yokoyama S, Tachibana K, Nakanishi H, Yamamoto Y, Irie K, Mandai K, Nagafuchi A, Monden M, Takai Y. Yokoyama S, et al. Among authors: nagafuchi a. Mol Biol Cell. 2001 Jun;12(6):1595-609. doi: 10.1091/mbc.12.6.1595. Mol Biol Cell. 2001. PMID: 11408571 Free PMC article.
The nectin-afadin complex has a potency to recruit the E-cadherin-beta-catenin complex through alpha-catenin in a manner independent of ponsin. ...Nectin showed a potency to recruit not only alpha-catenin but also ZO-1 to nectin-based cell-cell adhesion sites …
The nectin-afadin complex has a potency to recruit the E-cadherin-beta-catenin complex through alpha-catenin in a manner indep …
alpha-catenin-deficient F9 cells differentiate into signet ring cells.
Maeno Y, Moroi S, Nagashima H, Noda T, Shiozaki H, Monden M, Tsukita S, Nagafuchi A. Maeno Y, et al. Among authors: nagafuchi a. Am J Pathol. 1999 May;154(5):1323-8. doi: 10.1016/s0002-9440(10)65385-0. Am J Pathol. 1999. PMID: 10329584 Free PMC article.
We have provided clear evidence that a single mutation in the alpha-catenin gene may be a direct cause not only of the scattered properties of cells but also of signet ring cell formation in diffuse type adenocarcinoma....
We have provided clear evidence that a single mutation in the alpha-catenin gene may be a direct cause not only of the scatter …
Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1).
Furukawa Y, Nakatsuru S, Nagafuchi A, Tsukita S, Muto T, Nakamura Y, Horii A. Furukawa Y, et al. Among authors: nagafuchi a. Cytogenet Cell Genet. 1994;65(1-2):74-8. doi: 10.1159/000133603. Cytogenet Cell Genet. 1994. PMID: 8404069
We have isolated the human alpha-catenin gene (CTNNA1), which encodes a cadherin-associated protein, and have determined its primary structure and chromosomal localization. ...
We have isolated the human alpha-catenin gene (CTNNA1), which encodes a cadherin-associated protein, and have determined its primary …
Immunohistochemical evaluation of alpha-catenin expression in human gastric cancer.
Matsui S, Shiozaki H, Inoue M, Tamura S, Doki Y, Kadowaki T, Iwazawa T, Shimaya K, Nagafuchi A, Tsukita S, et al. Matsui S, et al. Among authors: nagafuchi a. Virchows Arch. 1994;424(4):375-81. doi: 10.1007/BF00190559. Virchows Arch. 1994. PMID: 8205352
E-cadherin (E-cad) plays a major role in the maintenance of cell-cell adhesion in epithelial tissues, and impaired E-cad expression correlates with tumour invasion and metastasis. ...
E-cadherin (E-cad) plays a major role in the maintenance of cell-cell adhesion in epithelial tissues, and impaired E-cad expression c …
Immunohistochemical detection of alpha-catenin expression in human cancers.
Shiozaki H, Iihara K, Oka H, Kadowaki T, Matsui S, Gofuku J, Inoue M, Nagafuchi A, Tsukita S, Mori T. Shiozaki H, et al. Among authors: nagafuchi a. Am J Pathol. 1994 Apr;144(4):667-74. Am J Pathol. 1994. PMID: 8160768 Free PMC article.
To determine whether possible downregulation of alpha-catenin expression may play a role in tumor invasion and metastasis through the dysfunction of E-cadherin, we investigated the expression of alpha-catenin in human carcinoma samples (esophagus, stomach, and colon) by im …
To determine whether possible downregulation of alpha-catenin expression may play a role in tumor invasion and metastasis through the …
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