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Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine.
Deng H, Bannister TD, Jin L, Babine RE, Quinn J, Nagafuji P, Celatka CA, Lin J, Lazarova TI, Rynkiewicz MJ, Bibbins F, Pandey P, Gorga J, Meyers HV, Abdel-Meguid SS, Strickler JE. Deng H, et al. Among authors: nagafuji p. Bioorg Med Chem Lett. 2006 Jun 1;16(11):3049-54. doi: 10.1016/j.bmcl.2006.02.052. Epub 2006 Mar 9. Bioorg Med Chem Lett. 2006. PMID: 16524727
Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants.
Lin J, Deng H, Jin L, Pandey P, Quinn J, Cantin S, Rynkiewicz MJ, Gorga JC, Bibbins F, Celatka CA, Nagafuji P, Bannister TD, Meyers HV, Babine RE, Hayward NJ, Weaver D, Benjamin H, Stassen F, Abdel-Meguid SS, Strickler JE. Lin J, et al. Among authors: nagafuji p. J Med Chem. 2006 Dec 28;49(26):7781-91. doi: 10.1021/jm060978s. J Med Chem. 2006. PMID: 17181160