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Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization.
Izumida Y, Yahagi N, Takeuchi Y, Nishi M, Shikama A, Takarada A, Masuda Y, Kubota M, Matsuzaka T, Nakagawa Y, Iizuka Y, Itaka K, Kataoka K, Shioda S, Niijima A, Yamada T, Katagiri H, Nagai R, Yamada N, Kadowaki T, Shimano H. Izumida Y, et al. Among authors: nagai r. Nat Commun. 2013;4:2316. doi: 10.1038/ncomms3316. Nat Commun. 2013. PMID: 23939267 Free PMC article.
In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.
Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y, Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga J, Shimano H. Takeuchi Y, et al. Among authors: nagai r. Biochem Biophys Res Commun. 2007 Nov 16;363(2):329-35. doi: 10.1016/j.bbrc.2007.08.165. Epub 2007 Sep 6. Biochem Biophys Res Commun. 2007. PMID: 17880923 Free article.
KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.
Takeuchi Y, Yahagi N, Aita Y, Murayama Y, Sawada Y, Piao X, Toya N, Oya Y, Shikama A, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Yamamoto T, Sekiya M, Matsuzaka T, Nakagawa Y, Urayama O, Kawakami Y, Iizuka Y, Gotoda T, Itaka K, Kataoka K, Nagai R, Kadowaki T, Yamada N, Lu Y, Jain MK, Shimano H. Takeuchi Y, et al. Among authors: nagai r. Cell Rep. 2016 Aug 30;16(9):2373-86. doi: 10.1016/j.celrep.2016.07.069. Epub 2016 Aug 18. Cell Rep. 2016. PMID: 27545894 Free PMC article.
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga J. Sekiya M, et al. Among authors: nagai r. Biochem Biophys Res Commun. 2009 Sep 25;387(3):511-5. doi: 10.1016/j.bbrc.2009.07.078. Epub 2009 Jul 18. Biochem Biophys Res Commun. 2009. PMID: 19619509
p53 involvement in the pathogenesis of fatty liver disease.
Yahagi N, Shimano H, Matsuzaka T, Sekiya M, Najima Y, Okazaki S, Okazaki H, Tamura Y, Iizuka Y, Inoue N, Nakagawa Y, Takeuchi Y, Ohashi K, Harada K, Gotoda T, Nagai R, Kadowaki T, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2004 May 14;279(20):20571-5. doi: 10.1074/jbc.M400884200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985341 Free article.
SREBP-1-independent regulation of lipogenic gene expression in adipocytes.
Sekiya M, Yahagi N, Matsuzaka T, Takeuchi Y, Nakagawa Y, Takahashi H, Okazaki H, Iizuka Y, Ohashi K, Gotoda T, Ishibashi S, Nagai R, Yamazaki T, Kadowaki T, Yamada N, Osuga J, Shimano H. Sekiya M, et al. Among authors: nagai r. J Lipid Res. 2007 Jul;48(7):1581-91. doi: 10.1194/jlr.M700033-JLR200. Epub 2007 Apr 24. J Lipid Res. 2007. PMID: 17456898 Free article.
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H. Takeuchi Y, et al. Among authors: nagai r. J Biol Chem. 2010 Apr 9;285(15):11681-91. doi: 10.1074/jbc.M109.096107. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145241 Free PMC article.
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis.
Okazaki H, Igarashi M, Nishi M, Tajima M, Sekiya M, Okazaki S, Yahagi N, Ohashi K, Tsukamoto K, Amemiya-Kudo M, Matsuzaka T, Shimano H, Yamada N, Aoki J, Morikawa R, Takanezawa Y, Arai H, Nagai R, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: nagai r. Diabetes. 2006 Jul;55(7):2091-7. doi: 10.2337/db05-0585. Diabetes. 2006. PMID: 16804080
1,776 results