Nagaoka H - Search Results

1

AID to overcome the limitations of genomic information.

Honjo T, Nagaoka H, Shinkura R, Muramatsu M. Honjo T, et al. Among authors: nagaoka h. Nat Immunol. 2005 Jul;6(7):655-61. doi: 10.1038/ni1218. Nat Immunol. 2005. PMID: 15970938 Review.

2

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation.

Nagaoka H, Muramatsu M, Yamamura N, Kinoshita K, Honjo T. Nagaoka H, et al. J Exp Med. 2002 Feb 18;195(4):529-34. doi: 10.1084/jem.20012144. J Exp Med. 2002. PMID: 11854365 Free PMC article.

3

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts.

Yoshikawa K, Okazaki IM, Eto T, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T. Yoshikawa K, et al. Among authors: nagaoka h. Science. 2002 Jun 14;296(5575):2033-6. doi: 10.1126/science.1071556. Science. 2002. PMID: 12065838

4

AID mutant analyses indicate requirement for class-switch-specific cofactors.

Ta VT, Nagaoka H, Catalan N, Durandy A, Fischer A, Imai K, Nonoyama S, Tashiro J, Ikegawa M, Ito S, Kinoshita K, Muramatsu M, Honjo T. Ta VT, et al. Among authors: nagaoka h. Nat Immunol. 2003 Sep;4(9):843-8. doi: 10.1038/ni964. Epub 2003 Aug 10. Nat Immunol. 2003. PMID: 12910268

5

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T. Shinkura R, et al. Among authors: nagaoka h. Nat Immunol. 2004 Jul;5(7):707-12. doi: 10.1038/ni1086. Epub 2004 Jun 13. Nat Immunol. 2004. PMID: 15195091

6

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination.

Begum NA, Kinoshita K, Muramatsu M, Nagaoka H, Shinkura R, Honjo T. Begum NA, et al. Among authors: nagaoka h. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13003-7. doi: 10.1073/pnas.0405219101. Epub 2004 Aug 18. Proc Natl Acad Sci U S A. 2004. PMID: 15317942 Free PMC article.

7

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch.

Begum NA, Kinoshita K, Kakazu N, Muramatsu M, Nagaoka H, Shinkura R, Biniszkiewicz D, Boyer LA, Jaenisch R, Honjo T. Begum NA, et al. Among authors: nagaoka h. Science. 2004 Aug 20;305(5687):1160-3. doi: 10.1126/science.1098444. Science. 2004. PMID: 15326357

8

DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase.

Nagaoka H, Ito S, Muramatsu M, Nakata M, Honjo T. Nagaoka H, et al. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2022-7. doi: 10.1073/pnas.0409491102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684068 Free PMC article.

9

Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID.

Wakae K, Magor BG, Saunders H, Nagaoka H, Kawamura A, Kinoshita K, Honjo T, Muramatsu M. Wakae K, et al. Among authors: nagaoka h. Int Immunol. 2006 Jan;18(1):41-7. doi: 10.1093/intimm/dxh347. Epub 2005 Nov 15. Int Immunol. 2006. PMID: 16291656

10

Negative regulation of activation-induced cytidine deaminase in B cells.

Muto T, Okazaki IM, Yamada S, Tanaka Y, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T. Muto T, et al. Among authors: nagaoka h. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2752-7. doi: 10.1073/pnas.0510970103. Epub 2006 Feb 13. Proc Natl Acad Sci U S A. 2006. PMID: 16477013 Free PMC article.

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