Nagashima H - Search Results

1

First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers.

Saito K, Nagashima H, Noguchi K, Yoshisue K, Yokogawa T, Matsushima E, Tahara T, Takagi S. Saito K, et al. Among authors: nagashima h. Cancer Chemother Pharmacol. 2014 Mar;73(3):577-83. doi: 10.1007/s00280-014-2383-2. Epub 2014 Jan 23. Cancer Chemother Pharmacol. 2014. PMID: 24452393 Clinical Trial.

2

Pharmacokinetics, Pharmacodynamics and Population Pharmacokinetic/Pharmacodynamic Modelling of Bilastine, a Second-Generation Antihistamine, in Healthy Japanese Subjects.

Togawa M, Yamaya H, Rodríguez M, Nagashima H. Togawa M, et al. Among authors: nagashima h. Clin Drug Investig. 2016 Dec;36(12):1011-1021. doi: 10.1007/s40261-016-0447-2. Clin Drug Investig. 2016. PMID: 27498100 Free PMC article. Clinical Trial.

3

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652, a Reversible Fatty Acid Amide Hydrolase Inhibitor, in Healthy, Nonelderly, Japanese Men and Elderly, Japanese Men and Women: A Randomized, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Phase I Study.

Takizawa M, Hatta T, Iitsuka H, Katashima M, Sato Y, Kuroishi K, Nagashima H. Takizawa M, et al. Among authors: nagashima h. Clin Ther. 2020 May;42(5):906-923. doi: 10.1016/j.clinthera.2020.03.021. Epub 2020 May 23. Clin Ther. 2020. PMID: 32456804 Clinical Trial.

4

Single- and multiple-ascending dose studies to evaluate the safety, tolerability, and pharmacokinetics of daclatasvir and asunaprevir in healthy male Japanese subjects.

Shiozaki T, Ueno T, Nagashima H, Yamahira N, Hiraoka M, Eley T, Bifano M, Bertz RJ. Shiozaki T, et al. Among authors: nagashima h. Int J Clin Pharmacol Ther. 2015 Apr;53(4):292-302. doi: 10.5414/CP202186. Int J Clin Pharmacol Ther. 2015. PMID: 25740262 Clinical Trial.

5

Pharmacodynamics of the glucagon-like peptide-1 receptor agonist lixisenatide in Japanese and Caucasian patients with type 2 diabetes mellitus poorly controlled on sulphonylureas with/without metformin.

Seino Y, Takami A, Boka G, Niemoeller E, Raccah D; PDY6797 investigators. Seino Y, et al. Diabetes Obes Metab. 2014 Aug;16(8):739-47. doi: 10.1111/dom.12276. Epub 2014 Mar 12. Diabetes Obes Metab. 2014. PMID: 24524806 Free PMC article. Clinical Trial.

6

Effect of Sucrose on Amino Acid Absorption of Whey: A Randomized Crossover Trial.

Wajiki M, Yamamoto T, Maruki-Uchida H, Nagashima H, Shimizu T, Morita M. Wajiki M, et al. Among authors: nagashima h. Metabolites. 2022 Mar 23;12(4):282. doi: 10.3390/metabo12040282. Metabolites. 2022. PMID: 35448469 Free PMC article.

7

Nasal glucagon as a viable alternative for treating insulin-induced hypoglycaemia in Japanese patients with type 1 or type 2 diabetes: A phase 3 randomized crossover study.

Matsuhisa M, Takita Y, Nasu R, Nagai Y, Ohwaki K, Nagashima H. Matsuhisa M, et al. Among authors: nagashima h. Diabetes Obes Metab. 2020 Jul;22(7):1167-1175. doi: 10.1111/dom.14019. Epub 2020 Apr 12. Diabetes Obes Metab. 2020. PMID: 32115879 Free PMC article. Clinical Trial.

8

Blood Glucose Response of a Low-Carbohydrate Oral Nutritional Supplement with Isomaltulose and Soluble Dietary Fiber in Individuals with Prediabetes: A Randomized, Single-Blind Crossover Trial.

Kokubo E, Morita S, Nagashima H, Oshio K, Iwamoto H, Miyaji K. Kokubo E, et al. Among authors: nagashima h. Nutrients. 2022 Jun 9;14(12):2386. doi: 10.3390/nu14122386. Nutrients. 2022. PMID: 35745116 Free PMC article. Clinical Trial.

9

Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction.

Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H. Otsuka Y, et al. Among authors: nagashima h. JCI Insight. 2024 Apr 22;9(8):e174179. doi: 10.1172/jci.insight.174179. JCI Insight. 2024. PMID: 38646933

10

Molecular Dynamics Study of the Microscopic Mechanical Balance at the Three-Phase Contact Line of Interfacial Nanobubble.

Jonosono Y, Tsuda SI, Tokumasu T, Nagashima H. Jonosono Y, et al. Among authors: nagashima h. Langmuir. 2024 Apr 23;40(16):8440-8449. doi: 10.1021/acs.langmuir.3c04027. Epub 2024 Apr 11. Langmuir. 2024. PMID: 38604804

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